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Items: 1 to 20 of 207

1.

PUMA overexpression induces reactive oxygen species generation and proteasome-mediated stathmin degradation in colorectal cancer cells.

Liu Z, Lu H, Shi H, Du Y, Yu J, Gu S, Chen X, Liu KJ, Hu CA.

Cancer Res. 2005 Mar 1;65(5):1647-54.

2.

Sp1 is involved in H2O2-induced PUMA gene expression and apoptosis in colorectal cancer cells.

Wang X, Wang J, Lin S, Geng Y, Wang J, Jiang B.

J Exp Clin Cancer Res. 2008 Sep 24;27:44. doi: 10.1186/1756-9966-27-44.

3.

Triggering of apoptosis by Puma is determined by the threshold set by prosurvival Bcl-2 family proteins.

Callus BA, Moujallad DM, Silke J, Gerl R, Jabbour AM, Ekert PG, Vaux DL.

J Mol Biol. 2008 Dec 12;384(2):313-23. doi: 10.1016/j.jmb.2008.09.041. Epub 2008 Sep 25.

PMID:
18835564
4.

Regulation of Bax activation and apoptotic response to microtubule-damaging agents by p53 transcription-dependent and -independent pathways.

Yamaguchi H, Chen J, Bhalla K, Wang HG.

J Biol Chem. 2004 Sep 17;279(38):39431-7. Epub 2004 Jul 19.

5.

Bax conformational change is a crucial step for PUMA-mediated apoptosis in human leukemia.

Liu FT, Newland AC, Jia L.

Biochem Biophys Res Commun. 2003 Oct 24;310(3):956-62.

PMID:
14550297
6.

Celecoxib induces p53-PUMA pathway for apoptosis in human colorectal cancer cells.

Liu HF, Hsiao PW, Chao JI.

Chem Biol Interact. 2008 Oct 22;176(1):48-57. doi: 10.1016/j.cbi.2008.07.012. Epub 2008 Aug 8.

PMID:
18760266
7.

Activation of p53/p21/PUMA alliance and disruption of PI-3/Akt in multimodal targeting of apoptotic signaling cascades in cervical cancer cells by a pentacyclic triterpenediol from Boswellia serrata.

Bhushan S, Malik F, Kumar A, Isher HK, Kaur IP, Taneja SC, Singh J.

Mol Carcinog. 2009 Dec;48(12):1093-108. doi: 10.1002/mc.20559.

PMID:
19544329
8.

6-Hydroxydopamine activates the mitochondrial apoptosis pathway through p38 MAPK-mediated, p53-independent activation of Bax and PUMA.

Gomez-Lazaro M, Galindo MF, Concannon CG, Segura MF, Fernandez-Gomez FJ, Llecha N, Comella JX, Prehn JH, Jordan J.

J Neurochem. 2008 Mar;104(6):1599-612. Epub 2007 Nov 6.

9.

Sulindac-derived reactive oxygen species induce apoptosis of human multiple myeloma cells via p38 mitogen activated protein kinase-induced mitochondrial dysfunction.

Seo SK, Lee HC, Woo SH, Jin HO, Yoo DH, Lee SJ, An S, Choe TB, Park MJ, Hong SI, Park IC, Rhee CH.

Apoptosis. 2007 Jan;12(1):195-209.

PMID:
17136320
11.

Apoptosis induced by proteasome inhibition in cancer cells: predominant role of the p53/PUMA pathway.

Concannon CG, Koehler BF, Reimertz C, Murphy BM, Bonner C, Thurow N, Ward MW, Villunger A, Strasser A, Kögel D, Prehn JH.

Oncogene. 2007 Mar 15;26(12):1681-92. Epub 2006 Sep 18.

PMID:
16983338
12.

Reactive oxygen species mediate doxorubicin induced p53-independent apoptosis.

Tsang WP, Chau SP, Kong SK, Fung KP, Kwok TT.

Life Sci. 2003 Sep 5;73(16):2047-58.

PMID:
12899928
13.

p53 initiates apoptosis by transcriptionally targeting the antiapoptotic protein ARC.

Li YZ, Lu DY, Tan WQ, Wang JX, Li PF.

Mol Cell Biol. 2008 Jan;28(2):564-74. Epub 2007 Nov 12.

14.

Induction of PUMA-alpha and down-regulation of PUMA-beta expression is associated with benzo(a)pyrene-induced apoptosis in MCF-7 cells.

Tampio M, Markkanen P, Puttonen KA, Hagelberg E, Heikkinen H, Huhtinen K, Loikkanen J, Hirvonen MR, Vähäkangas KH.

Toxicol Lett. 2009 Aug 10;188(3):214-22. doi: 10.1016/j.toxlet.2009.04.016. Epub 2009 May 3.

PMID:
19397966
15.
16.

Bax activation by the BH3-only protein Puma promotes cell dependence on antiapoptotic Bcl-2 family members.

Gallenne T, Gautier F, Oliver L, Hervouet E, Noël B, Hickman JA, Geneste O, Cartron PF, Vallette FM, Manon S, Juin P.

J Cell Biol. 2009 Apr 20;185(2):279-90. doi: 10.1083/jcb.200809153.

17.

BH3-only proapoptotic Bcl-2 family members Noxa and Puma mediate neural precursor cell death.

Akhtar RS, Geng Y, Klocke BJ, Latham CB, Villunger A, Michalak EM, Strasser A, Carroll SL, Roth KA.

J Neurosci. 2006 Jul 5;26(27):7257-64.

19.

Reactive oxygen species up-regulates cyclooxygenase-2, p53, and Bax mRNA expression in bovine luteal cells.

Nakamura T, Sakamoto K.

Biochem Biophys Res Commun. 2001 Jun 1;284(1):203-10.

PMID:
11374891
20.

Regulation of PUMA-alpha by p53 in cisplatin-induced renal cell apoptosis.

Jiang M, Wei Q, Wang J, Du Q, Yu J, Zhang L, Dong Z.

Oncogene. 2006 Jul 6;25(29):4056-66. Epub 2006 Feb 20.

PMID:
16491117

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