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Items: 1 to 20 of 104

1.

An in vitro selection system for TNA.

Ichida JK, Zou K, Horhota A, Yu B, McLaughlin LW, Szostak JW.

J Am Chem Soc. 2005 Mar 9;127(9):2802-3.

2.

DNA polymerase-mediated DNA synthesis on a TNA template.

Chaput JC, Ichida JK, Szostak JW.

J Am Chem Soc. 2003 Jan 29;125(4):856-7.

PMID:
12537469
3.

TNA synthesis by DNA polymerases.

Chaput JC, Szostak JW.

J Am Chem Soc. 2003 Aug 6;125(31):9274-5.

PMID:
12889939
4.

An In Vitro Selection Protocol for Threose Nucleic Acid (TNA) Using DNA Display.

Dunn MR, Chaput JC.

Curr Protoc Nucleic Acid Chem. 2014 Jun 24;57:9.8.1-19. doi: 10.1002/0471142700.nc0908s57. Review.

PMID:
24961723
5.

Kinetic analysis of an efficient DNA-dependent TNA polymerase.

Horhota A, Zou K, Ichida JK, Yu B, McLaughlin LW, Szostak JW, Chaput JC.

J Am Chem Soc. 2005 May 25;127(20):7427-34.

6.

High fidelity TNA synthesis by Therminator polymerase.

Ichida JK, Horhota A, Zou K, McLaughlin LW, Szostak JW.

Nucleic Acids Res. 2005 Sep 12;33(16):5219-25. Print 2005.

7.

Synthesis and enzymatic incorporation of α-L-threofuranosyl adenine triphosphate (tATP).

Zhang S, Chaput JC.

Bioorg Med Chem Lett. 2013 Mar 1;23(5):1447-9. doi: 10.1016/j.bmcl.2012.12.080. Epub 2013 Jan 5.

PMID:
23352269
8.

DNA polymerase-mediated synthesis of unbiased threose nucleic acid (TNA) polymers requires 7-deazaguanine to suppress G:G mispairing during TNA transcription.

Dunn MR, Larsen AC, Zahurancik WJ, Fahmi NE, Meyers M, Suo Z, Chaput JC.

J Am Chem Soc. 2015 Apr 1;137(12):4014-7. doi: 10.1021/ja511481n. Epub 2015 Mar 20.

PMID:
25785966
9.

Synthesis of threose nucleic acid (TNA) triphosphates and oligonucleotides by polymerase-mediated primer extension.

Zhang S, Yu H, Chaput JC.

Curr Protoc Nucleic Acid Chem. 2013 Mar;Chapter 4:Unit 4.54. doi: 10.1002/0471142700.nc0454s52.

PMID:
23512696
10.

Structural Insights into Conformation Differences between DNA/TNA and RNA/TNA Chimeric Duplexes.

Anosova I, Kowal EA, Sisco NJ, Sau S, Liao JY, Bala S, Rozners E, Egli M, Chaput JC, Van Horn WD.

Chembiochem. 2016 Sep 15;17(18):1705-8. doi: 10.1002/cbic.201600349. Epub 2016 Jul 29.

11.

A Scalable Synthesis of α-L-Threose Nucleic Acid Monomers.

Sau SP, Fahmi NE, Liao JY, Bala S, Chaput JC.

J Org Chem. 2016 Mar 18;81(6):2302-7. doi: 10.1021/acs.joc.5b02768. Epub 2016 Feb 26.

PMID:
26895480
12.

Darwinian evolution of an alternative genetic system provides support for TNA as an RNA progenitor.

Yu H, Zhang S, Chaput JC.

Nat Chem. 2012 Jan 10;4(3):183-7. doi: 10.1038/nchem.1241.

PMID:
22354431
13.

Expanding the chemical diversity of TNA with tUTP derivatives that are substrates for a TNA polymerase.

Mei H, Chaput JC.

Chem Commun (Camb). 2018 Jan 31;54(10):1237-1240. doi: 10.1039/c7cc09130c.

PMID:
29340357
14.

The structure of a TNA-TNA complex in solution: NMR study of the octamer duplex derived from alpha-(L)-threofuranosyl-(3'-2')-CGAATTCG.

Ebert MO, Mang C, Krishnamurthy R, Eschenmoser A, Jaun B.

J Am Chem Soc. 2008 Nov 12;130(45):15105-15. doi: 10.1021/ja8041959. Epub 2008 Oct 18.

PMID:
18928287
15.

Experimental evidence that GNA and TNA were not sequential polymers in the prebiotic evolution of RNA.

Yang YW, Zhang S, McCullum EO, Chaput JC.

J Mol Evol. 2007 Sep;65(3):289-95. Epub 2007 Sep 9.

PMID:
17828568
16.
17.

Synthesis and polymerase activity of a fluorescent cytidine TNA triphosphate analogue.

Mei H, Shi C, Jimenez RM, Wang Y, Kardouh M, Chaput JC.

Nucleic Acids Res. 2017 Jun 2;45(10):5629-5638. doi: 10.1093/nar/gkx368.

18.

Chemical etiology of nucleic acid structure: the alpha-threofuranosyl-(3'-->2') oligonucleotide system.

Schöning K, Scholz P, Guntha S, Wu X, Krishnamurthy R, Eschenmoser A.

Science. 2000 Nov 17;290(5495):1347-51.

19.

A parallel stranded G-quadruplex composed of threose nucleic acid (TNA).

Liao JY, Anosova I, Bala S, Van Horn WD, Chaput JC.

Biopolymers. 2017 Mar;107(3). doi: 10.1002/bip.22999.

PMID:
27718227
20.

Synthesis and nonenzymatic template-directed polymerization of 2'-amino-2'-deoxythreose nucleotides.

Blain JC, Ricardo A, Szostak JW.

J Am Chem Soc. 2014 Feb 5;136(5):2033-9. doi: 10.1021/ja411950n. Epub 2014 Jan 22.

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