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Items: 1 to 20 of 82

1.

Endothelial lipase is inactivated upon cleavage by the members of the proprotein convertase family.

Gauster M, Hrzenjak A, Schick K, Frank S.

J Lipid Res. 2005 May;46(5):977-87. Epub 2005 Feb 1.

2.

Proprotein convertases [corrected] are responsible for proteolysis and inactivation of endothelial lipase.

Jin W, Fuki IV, Seidah NG, Benjannet S, Glick JM, Rader DJ.

J Biol Chem. 2005 Nov 4;280(44):36551-9. Epub 2005 Aug 18. Erratum in: J Biol Chem. 2005 Dec 9;280(49):41124.

3.

Furin is the primary in vivo convertase of angiopoietin-like 3 and endothelial lipase in hepatocytes.

Essalmani R, Susan-Resiga D, Chamberland A, Asselin MC, Canuel M, Constam D, Creemers JW, Day R, Gauthier D, Prat A, Seidah NG.

J Biol Chem. 2013 Sep 13;288(37):26410-8. doi: 10.1074/jbc.M113.501304. Epub 2013 Aug 5.

5.

Processing of alpha4 integrin by the proprotein convertases: histidine at position P6 regulates cleavage.

Bergeron E, Basak A, Decroly E, Seidah NG.

Biochem J. 2003 Jul 15;373(Pt 2):475-84.

6.

Hepatic proprotein convertases modulate HDL metabolism.

Jin W, Wang X, Millar JS, Quertermous T, Rothblat GH, Glick JM, Rader DJ.

Cell Metab. 2007 Aug;6(2):129-36.

7.

Engineering of α1-antitrypsin variants with improved specificity for the proprotein convertase furin using site-directed random mutagenesis.

Hada K, Isshiki K, Matsuda S, Yuasa K, Tsuji A.

Protein Eng Des Sel. 2013 Feb;26(2):123-31. doi: 10.1093/protein/gzs091. Epub 2012 Nov 14.

PMID:
23155057
8.

Comparative processing of bovine leukemia virus envelope glycoprotein gp72 by subtilisin/kexin-like mammalian convertases.

Zarkik S, Decroly E, Wattiez R, Seidah NG, Burny A, Ruysschaert JM.

FEBS Lett. 1997 Apr 7;406(1-2):205-10.

9.

Regulation of the stepwise proteolytic cleavage and secretion of PDGF-B by the proprotein convertases.

Siegfried G, Basak A, Prichett-Pejic W, Scamuffa N, Ma L, Benjannet S, Veinot JP, Calvo F, Seidah N, Khatib AM.

Oncogene. 2005 Oct 20;24(46):6925-35.

PMID:
16007151
11.

Alpha1-antitrypsin Portland inhibits processing of precursors mediated by proprotein convertases primarily within the constitutive secretory pathway.

Benjannet S, Savaria D, Laslop A, Munzer JS, Chrétien M, Marcinkiewicz M, Seidah NG.

J Biol Chem. 1997 Oct 17;272(42):26210-8.

12.

Furin, PC1/3, and/or PC6A process rabbit, but not human, pro-lactase-phlorizin hydrolase to the 180-kDa intermediate.

Keller P, Zecca L, Boukamel R, Zwicker E, Gloor S, Semenza G.

J Biol Chem. 1995 Oct 27;270(43):25722-8.

13.

The proprotein convertases and their implication in sterol and/or lipid metabolism.

Seidah NG, Khatib AM, Prat A.

Biol Chem. 2006 Jul;387(7):871-7. Review.

PMID:
16913836
14.
15.

Selective inhibition of proprotein convertases represses the metastatic potential of human colorectal tumor cells.

Scamuffa N, Siegfried G, Bontemps Y, Ma L, Basak A, Cherel G, Calvo F, Seidah NG, Khatib AM.

J Clin Invest. 2008 Jan;118(1):352-63.

16.

The regulated cell surface zymogen activation of the proprotein convertase PC5A directs the processing of its secretory substrates.

Mayer G, Hamelin J, Asselin MC, Pasquato A, Marcinkiewicz E, Tang M, Tabibzadeh S, Seidah NG.

J Biol Chem. 2008 Jan 25;283(4):2373-84. Epub 2007 Nov 26.

17.

Identification of prodomain determinants involved in ADAMTS-1 biosynthesis.

Longpré JM, Leduc R.

J Biol Chem. 2004 Aug 6;279(32):33237-45. Epub 2004 Jun 7.

18.

Endothelial lipase promotes the catabolism of ApoB-containing lipoproteins.

Broedl UC, Maugeais C, Millar JS, Jin W, Moore RE, Fuki IV, Marchadier D, Glick JM, Rader DJ.

Circ Res. 2004 Jun 25;94(12):1554-61. Epub 2004 Apr 29.

19.

Structural basis of endothelial lipase tropism for HDL.

Broedl UC, Jin W, Fuki IV, Glick JM, Rader DJ.

FASEB J. 2004 Dec;18(15):1891-3. Epub 2004 Sep 28.

PMID:
15456739
20.

Subtilisin-like proprotein convertases, PACE4 and PC8, as well as furin, are endogenous proalbumin convertases in HepG2 cells.

Mori K, Imamaki A, Nagata K, Yonetomi Y, Kiyokage-Yoshimoto R, Martin TJ, Gillespie MT, Nagahama M, Tsuji A, Matsuda Y.

J Biochem. 1999 Mar;125(3):627-33.

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