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Items: 1 to 20 of 545

1.

Structural and kinetic characterization of active-site histidine as a proton shuttle in catalysis by human carbonic anhydrase II.

Fisher Z, Hernandez Prada JA, Tu C, Duda D, Yoshioka C, An H, Govindasamy L, Silverman DN, McKenna R.

Biochemistry. 2005 Feb 1;44(4):1097-105.

PMID:
15667203
2.

Speeding up proton transfer in a fast enzyme: kinetic and crystallographic studies on the effect of hydrophobic amino acid substitutions in the active site of human carbonic anhydrase II.

Fisher SZ, Tu C, Bhatt D, Govindasamy L, Agbandje-McKenna M, McKenna R, Silverman DN.

Biochemistry. 2007 Mar 27;46(12):3803-13. Epub 2007 Mar 2.

PMID:
17330962
3.

Proton transfer in a Thr200His mutant of human carbonic anhydrase II.

Bhatt D, Tu C, Fisher SZ, Hernandez Prada JA, McKenna R, Silverman DN.

Proteins. 2005 Nov 1;61(2):239-45.

PMID:
16106378
4.

Structural and kinetic analysis of the chemical rescue of the proton transfer function of carbonic anhydrase II.

Duda D, Tu C, Qian M, Laipis P, Agbandje-McKenna M, Silverman DN, McKenna R.

Biochemistry. 2001 Feb 13;40(6):1741-8.

PMID:
11327835
5.

Kinetic analysis of multiple proton shuttles in the active site of human carbonic anhydrase.

Tu C, Qian M, An H, Wadhwa NR, Duda D, Yoshioka C, Pathak Y, McKenna R, Laipis PJ, Silverman DN.

J Biol Chem. 2002 Oct 11;277(41):38870-6. Epub 2002 Aug 8.

6.

Structural and kinetic analysis of proton shuttle residues in the active site of human carbonic anhydrase III.

Elder I, Fisher Z, Laipis PJ, Tu C, McKenna R, Silverman DN.

Proteins. 2007 Jul 1;68(1):337-43.

PMID:
17427958
7.

Solvent-mediated proton transfer in catalysis by carbonic anhydrase.

Silverman DN, McKenna R.

Acc Chem Res. 2007 Aug;40(8):669-75. Epub 2007 Jun 6.

PMID:
17550224
8.

Chemical rescue of proton transfer in catalysis by carbonic anhydrases in the beta- and gamma-class.

Tu C, Rowlett RS, Tripp BC, Ferry JG, Silverman DN.

Biochemistry. 2002 Dec 24;41(51):15429-35.

PMID:
12484784
9.

Proton transfer from exogenous donors in catalysis by human carbonic anhydrase II.

Elder I, Tu C, Ming LJ, McKenna R, Silverman DN.

Arch Biochem Biophys. 2005 May 1;437(1):106-14.

PMID:
15820222
10.

Chemical rescue in catalysis by human carbonic anhydrases II and III.

An H, Tu C, Duda D, Montanez-Clemente I, Math K, Laipis PJ, McKenna R, Silverman DN.

Biochemistry. 2002 Mar 5;41(9):3235-42.

PMID:
11863462
11.

Atomic crystal and molecular dynamics simulation structures of human carbonic anhydrase II: insights into the proton transfer mechanism.

Fisher SZ, Maupin CM, Budayova-Spano M, Govindasamy L, Tu C, Agbandje-McKenna M, Silverman DN, Voth GA, McKenna R.

Biochemistry. 2007 Mar 20;46(11):2930-7. Epub 2007 Feb 24.

PMID:
17319692
12.

Comparison of intra- and intermolecular proton transfer in human carbonic anhydrase II.

Taoka S, Tu C, Kistler KA, Silverman DN.

J Biol Chem. 1994 Jul 8;269(27):17988-92.

13.

Activation of carbonic anhydrase II by active-site incorporation of histidine analogs.

Elder I, Han S, Tu C, Steele H, Laipis PJ, Viola RE, Silverman DN.

Arch Biochem Biophys. 2004 Jan 15;421(2):283-9.

PMID:
14984209
14.

Role of hydrophilic residues in proton transfer during catalysis by human carbonic anhydrase II.

Zheng J, Avvaru BS, Tu C, McKenna R, Silverman DN.

Biochemistry. 2008 Nov 18;47(46):12028-36. doi: 10.1021/bi801473w. Epub 2008 Oct 23.

15.

Water networks in fast proton transfer during catalysis by human carbonic anhydrase II.

Mikulski R, West D, Sippel KH, Avvaru BS, Aggarwal M, Tu C, McKenna R, Silverman DN.

Biochemistry. 2013 Jan 8;52(1):125-31. doi: 10.1021/bi301099k. Epub 2012 Dec 18.

16.

Glutamate and aspartate as proton shuttles in mutants of carbonic anhydrase.

Qian M, Tu C, Earnhardt JN, Laipis PJ, Silverman DN.

Biochemistry. 1997 Dec 16;36(50):15758-64.

PMID:
9398305
17.

Intramolecular proton transfer from multiple sites in catalysis by murine carbonic anhydrase V.

Earnhardt JN, Qian M, Tu C, Laipis PJ, Silverman DN.

Biochemistry. 1998 May 19;37(20):7649-55.

PMID:
9585580
18.

Bicarbonate as a proton donor in catalysis by Zn(II)- and Co(II)-containing carbonic anhydrases.

Tu C, Tripp BC, Ferry JG, Silverman DN.

J Am Chem Soc. 2001 Jun 27;123(25):5861-6.

PMID:
11414818
19.

Structural and kinetic study of the extended active site for proton transfer in human carbonic anhydrase II.

Domsic JF, Williams W, Fisher SZ, Tu C, Agbandje-McKenna M, Silverman DN, McKenna R.

Biochemistry. 2010 Aug 3;49(30):6394-9. doi: 10.1021/bi1007645.

20.

Kinetic isotope effects for concerted multiple proton transfer: a direct dynamics study of an active-site model of carbonic anhydrase II.

Smedarchina Z, Siebrand W, Fernández-Ramos A, Cui Q.

J Am Chem Soc. 2003 Jan 8;125(1):243-51.

PMID:
12515527

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