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Items: 1 to 20 of 180

1.

Phosphorylation of RasGRP3 on threonine 133 provides a mechanistic link between PKC and Ras signaling systems in B cells.

Zheng Y, Liu H, Coughlin J, Zheng J, Li L, Stone JC.

Blood. 2005 May 1;105(9):3648-54. Epub 2005 Jan 18.

2.

Integration of DAG signaling systems mediated by PKC-dependent phosphorylation of RasGRP3.

Teixeira C, Stang SL, Zheng Y, Beswick NS, Stone JC.

Blood. 2003 Aug 15;102(4):1414-20. Epub 2003 May 1.

3.

RasGRP1 and RasGRP3 regulate B cell proliferation by facilitating B cell receptor-Ras signaling.

Coughlin JJ, Stang SL, Dower NA, Stone JC.

J Immunol. 2005 Dec 1;175(11):7179-84.

4.
5.

Activation of RasGRP3 by phosphorylation of Thr-133 is required for B cell receptor-mediated Ras activation.

Aiba Y, Oh-hora M, Kiyonaka S, Kimura Y, Hijikata A, Mori Y, Kurosaki T.

Proc Natl Acad Sci U S A. 2004 Nov 23;101(47):16612-7. Epub 2004 Nov 15.

6.

Differential membrane binding and diacylglycerol recognition by C1 domains of RasGRPs.

Johnson JE, Goulding RE, Ding Z, Partovi A, Anthony KV, Beaulieu N, Tazmini G, Cornell RB, Kay RJ.

Biochem J. 2007 Sep 1;406(2):223-36.

7.

RasGRP links T-cell receptor signaling to Ras.

Ebinu JO, Stang SL, Teixeira C, Bottorff DA, Hooton J, Blumberg PM, Barry M, Bleakley RC, Ostergaard HL, Stone JC.

Blood. 2000 May 15;95(10):3199-203.

8.

Regulation of Ras in lymphocytes: get a GRP.

Stone JC.

Biochem Soc Trans. 2006 Nov;34(Pt 5):858-61.

PMID:
17052215
9.

A diacylglycerol-protein kinase C-RasGRP1 pathway directs Ras activation upon antigen receptor stimulation of T cells.

Roose JP, Mollenauer M, Gupta VA, Stone J, Weiss A.

Mol Cell Biol. 2005 Jun;25(11):4426-41.

10.

The role of RasGRPs in regulation of lymphocyte proliferation.

Coughlin JJ, Stang SL, Dower NA, Stone JC.

Immunol Lett. 2006 May 15;105(1):77-82. Epub 2006 Feb 20.

PMID:
16530850
11.

Ras activation in response to phorbol ester proceeds independently of the EGFR via an unconventional nucleotide-exchange factor system in COS-7 cells.

Rubio I, Rennert K, Wittig U, Beer K, Dürst M, Stang SL, Stone J, Wetzker R.

Biochem J. 2006 Sep 1;398(2):243-56.

12.

Diacylglycerol kinase zeta regulates Ras activation by a novel mechanism.

Topham MK, Prescott SM.

J Cell Biol. 2001 Mar 19;152(6):1135-43.

13.

[RasGRP proteins--Ras-activating factors].

Szamałek M, Baer-Dubowska W.

Postepy Biochem. 2007;53(2):112-20. Review. Polish.

PMID:
17969871
14.

Requirement for Ras guanine nucleotide releasing protein 3 in coupling phospholipase C-gamma2 to Ras in B cell receptor signaling.

Oh-hora M, Johmura S, Hashimoto A, Hikida M, Kurosaki T.

J Exp Med. 2003 Dec 15;198(12):1841-51.

15.

Phorbol esters modulate the Ras exchange factor RasGRP3.

Lorenzo PS, Kung JW, Bottorff DA, Garfield SH, Stone JC, Blumberg PM.

Cancer Res. 2001 Feb 1;61(3):943-9.

16.

T cell activation in vivo targets diacylglycerol kinase alpha to the membrane: a novel mechanism for Ras attenuation.

Sanjuán MA, Pradet-Balade B, Jones DR, Martínez-A C, Stone JC, Garcia-Sanz JA, Mérida I.

J Immunol. 2003 Mar 15;170(6):2877-83.

18.

The lymphocyte function-associated antigen-1 receptor costimulates plasma membrane Ras via phospholipase D2.

Mor A, Campi G, Du G, Zheng Y, Foster DA, Dustin ML, Philips MR.

Nat Cell Biol. 2007 Jun;9(6):713-9. Epub 2007 May 7.

PMID:
17486117
19.

Functional links between diacylglycerol and phosphatidylinositol signaling systems in human leukocyte-derived cell lines.

Poon HY, Stone JC.

Biochem Biophys Res Commun. 2009 Dec 25;390(4):1395-401. doi: 10.1016/j.bbrc.2009.11.004. Epub 2009 Nov 5.

PMID:
19896467
20.

Dual phospholipase C/diacylglycerol requirement for protein kinase D1 activation in lymphocytes.

Wood CD, Marklund U, Cantrell DA.

J Biol Chem. 2005 Feb 18;280(7):6245-51. Epub 2004 Dec 7.

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