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Items: 1 to 20 of 107

2.
3.

A new and efficient DNA enzyme for the sequence-specific cleavage of RNA.

Feldman AR, Sen D.

J Mol Biol. 2001 Oct 19;313(2):283-94.

PMID:
11800557
4.

Investigation of the catalytic mechanism of a synthetic DNAzyme with protein-like functionality: an RNaseA mimic?

Thomas JM, Yoon JK, Perrin DM.

J Am Chem Soc. 2009 Apr 22;131(15):5648-58. doi: 10.1021/ja900125n.

PMID:
20560639
6.

Toward the combinatorial selection of chemically modified DNAzyme RNase A mimics active against all-RNA substrates.

Hollenstein M, Hipolito CJ, Lam CH, Perrin DM.

ACS Comb Sci. 2013 Apr 8;15(4):174-82. doi: 10.1021/co3001378. Epub 2013 Mar 13.

PMID:
23485334
7.

A lead-dependent DNAzyme with a two-step mechanism.

Brown AK, Li J, Pavot CM, Lu Y.

Biochemistry. 2003 Jun 17;42(23):7152-61.

PMID:
12795611
8.
9.

A self-cleaving DNA enzyme modified with amines, guanidines and imidazoles operates independently of divalent metal cations (M2+).

Hollenstein M, Hipolito CJ, Lam CH, Perrin DM.

Nucleic Acids Res. 2009 Apr;37(5):1638-49. doi: 10.1093/nar/gkn1070. Epub 2009 Jan 19.

10.

Toward an RNaseA mimic: A DNAzyme with imidazoles and cationic amines.

Lermer L, Roupioz Y, Ting R, Perrin DM.

J Am Chem Soc. 2002 Aug 28;124(34):9960-1.

PMID:
12188639
11.

RNA-cleaving DNA enzymes with altered regio- or enantioselectivity.

Ordoukhanian P, Joyce GF.

J Am Chem Soc. 2002 Oct 23;124(42):12499-506.

PMID:
12381192
12.
13.

A divalent metal-dependent self-cleaving DNAzyme with a tyrosine side chain.

Lam CH, Hipolito CJ, Hollenstein M, Perrin DM.

Org Biomol Chem. 2011 Oct 21;9(20):6949-54. doi: 10.1039/c1ob05359k. Epub 2011 Jun 13.

PMID:
21670811
15.

Ribonuclease P catalysis requires Mg2+ coordinated to the pro-RP oxygen of the scissile bond.

Chen Y, Li X, Gegenheimer P.

Biochemistry. 1997 Mar 4;36(9):2425-38.

PMID:
9054547
16.

Protein-inspired modified DNAzymes: dramatic effects of shortening side-chain length of 8-imidazolyl modified deoxyadenosines in selecting RNaseA mimicking DNAzymes.

Hipolito CJ, Hollenstein M, Lam CH, Perrin DM.

Org Biomol Chem. 2011 Apr 7;9(7):2266-73. doi: 10.1039/c0ob00595a. Epub 2011 Feb 10.

PMID:
21311779
17.

A versatile endoribonuclease mimic made of DNA: characteristics and applications of the 8-17 RNA-cleaving DNAzyme.

Schlosser K, Li Y.

Chembiochem. 2010 May 3;11(7):866-79. doi: 10.1002/cbic.200900786. Review.

PMID:
20213779
20.

High affinity DNAzyme-based ligands for transition metal cations - a prototype sensor for Hg2+.

Thomas JM, Ting R, Perrin DM.

Org Biomol Chem. 2004 Feb 7;2(3):307-12. Epub 2004 Jan 14.

PMID:
14747858

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