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Items: 1 to 20 of 364

1.

MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors.

Huntly BJ, Shigematsu H, Deguchi K, Lee BH, Mizuno S, Duclos N, Rowan R, Amaral S, Curley D, Williams IR, Akashi K, Gilliland DG.

Cancer Cell. 2004 Dec;6(6):587-96.

2.

Chronic versus acute myelogenous leukemia: a question of self-renewal.

Jamieson CH, Weissman IL, Passegué E.

Cancer Cell. 2004 Dec;6(6):531-3.

3.

Prenatal and postnatal myeloid cells demonstrate stepwise progression in the pathogenesis of MLL fusion gene leukemia.

Johnson JJ, Chen W, Hudson W, Yao Q, Taylor M, Rabbitts TH, Kersey JH.

Blood. 2003 Apr 15;101(8):3229-35. Epub 2002 Dec 19.

4.

HOXB6 overexpression in murine bone marrow immortalizes a myelomonocytic precursor in vitro and causes hematopoietic stem cell expansion and acute myeloid leukemia in vivo.

Fischbach NA, Rozenfeld S, Shen W, Fong S, Chrobak D, Ginzinger D, Kogan SC, Radhakrishnan A, Le Beau MM, Largman C, Lawrence HJ.

Blood. 2005 Feb 15;105(4):1456-66. Epub 2004 Nov 2.

5.

Plzf drives MLL-fusion-mediated leukemogenesis specifically in long-term hematopoietic stem cells.

Ono R, Masuya M, Nakajima H, Enomoto Y, Miyata E, Nakamura A, Ishii S, Suzuki K, Shibata-Minoshima F, Katayama N, Kitamura T, Nosaka T.

Blood. 2013 Aug 15;122(7):1271-83. doi: 10.1182/blood-2012-09-456665. Epub 2013 Jul 9.

6.

Primitive interleukin 3 null hematopoietic cells transduced with BCR-ABL show accelerated loss after culture of factor-independence in vitro and leukemogenic activity in vivo.

Jiang X, Ng E, Yip C, Eisterer W, Chalandon Y, Stuible M, Eaves A, Eaves CJ.

Blood. 2002 Nov 15;100(10):3731-40. Epub 2002 Jul 5.

7.

Transformation from committed progenitor to leukemia stem cells.

Krivtsov AV, Feng Z, Armstrong SA.

Ann N Y Acad Sci. 2009 Sep;1176:144-9. doi: 10.1111/j.1749-6632.2009.04966.x.

PMID:
19796242
8.

A primitive hematopoietic cell is the target for the leukemic transformation in human philadelphia-positive acute lymphoblastic leukemia.

Cobaleda C, Gutiérrez-Cianca N, Pérez-Losada J, Flores T, García-Sanz R, González M, Sánchez-García I.

Blood. 2000 Feb 1;95(3):1007-13.

9.

Autocrine and paracrine effects of an ES-cell derived, BCR/ABL-transformed hematopoietic cell line that induces leukemia in mice.

Peters DG, Klucher KM, Perlingeiro RC, Dessain SK, Koh EY, Daley GQ.

Oncogene. 2001 May 10;20(21):2636-46.

10.

ABL oncogenes directly stimulate two distinct target cells in bone marrow from 5-fluorouracil-treated mice.

Kelliher MA, Weckstein DJ, Knott AG, Wortis HH, Rosenberg N.

Oncogene. 1993 May;8(5):1249-56.

PMID:
8479746
11.

Inducible chronic phase of myeloid leukemia with expansion of hematopoietic stem cells in a transgenic model of BCR-ABL leukemogenesis.

Koschmieder S, Göttgens B, Zhang P, Iwasaki-Arai J, Akashi K, Kutok JL, Dayaram T, Geary K, Green AR, Tenen DG, Huettner CS.

Blood. 2005 Jan 1;105(1):324-34. Epub 2004 Aug 26.

12.

MLL-ENL causes a reversible and myc-dependent block of myelomonocytic cell differentiation.

Schreiner S, Birke M, García-Cuéllar MP, Zilles O, Greil J, Slany RK.

Cancer Res. 2001 Sep 1;61(17):6480-6.

13.

IGF signaling contributes to malignant transformation of hematopoietic progenitors by the MLL-AF9 oncoprotein.

Jenkins CR, Shevchuk OO, Giambra V, Lam SH, Carboni JM, Gottardis MM, Holzenberger M, Pollak M, Humphries RK, Weng AP.

Exp Hematol. 2012 Sep;40(9):715-723.e6. doi: 10.1016/j.exphem.2012.05.003. Epub 2012 May 18.

PMID:
22613471
14.

Mixed lineage leukemia translocations and a leukemia stem cell program.

Faber J, Armstrong SA.

Cancer Res. 2007 Sep 15;67(18):8425-8. Review.

15.

SCL expression at critical points in human hematopoietic lineage commitment.

Zhang Y, Payne KJ, Zhu Y, Price MA, Parrish YK, Zielinska E, Barsky LW, Crooks GM.

Stem Cells. 2005 Jun-Jul;23(6):852-60.

16.

E2a/Pbx1 oncogene inhibits terminal differentiation but not myeloid potential of pro-T cells.

Bourette RP, Grasset MF, Mouchiroud G.

Oncogene. 2007 Jan 11;26(2):234-47. Epub 2006 Jul 3.

PMID:
16819510
17.

AML1-ETO rapidly induces acute myeloblastic leukemia in cooperation with the Wilms tumor gene, WT1.

Nishida S, Hosen N, Shirakata T, Kanato K, Yanagihara M, Nakatsuka S, Hoshida Y, Nakazawa T, Harada Y, Tatsumi N, Tsuboi A, Kawakami M, Oka Y, Oji Y, Aozasa K, Kawase I, Sugiyama H.

Blood. 2006 Apr 15;107(8):3303-12. Epub 2005 Dec 27.

18.

Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9.

Krivtsov AV, Twomey D, Feng Z, Stubbs MC, Wang Y, Faber J, Levine JE, Wang J, Hahn WC, Gilliland DG, Golub TR, Armstrong SA.

Nature. 2006 Aug 17;442(7104):818-22. Epub 2006 Jul 16.

PMID:
16862118
19.

STAT5 is crucial to maintain leukemic stem cells in acute myelogenous leukemias induced by MOZ-TIF2.

Tam WF, Hähnel PS, Schüler A, Lee BH, Okabe R, Zhu N, Pante SV, Raffel G, Mercher T, Wernig G, Bockamp E, Sasca D, Kreft A, Robinson GW, Hennighausen L, Gilliland DG, Kindler T.

Cancer Res. 2013 Jan 1;73(1):373-84. doi: 10.1158/0008-5472.CAN-12-0255. Epub 2012 Nov 13.

20.

Leukemic stem cells in childhood high-risk ALL/t(9;22) and t(4;11) are present in primitive lymphoid-restricted CD34+CD19- cells.

Hotfilder M, Röttgers S, Rosemann A, Schrauder A, Schrappe M, Pieters R, Jürgens H, Harbott J, Vormoor J.

Cancer Res. 2005 Feb 15;65(4):1442-9.

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