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Items: 1 to 20 of 140

1.

Negative regulation of EGFR signalling through integrin-alpha1beta1-mediated activation of protein tyrosine phosphatase TCPTP.

Mattila E, Pellinen T, Nevo J, Vuoriluoto K, Arjonen A, Ivaska J.

Nat Cell Biol. 2005 Jan;7(1):78-85. Epub 2004 Dec 12.

PMID:
15592458
2.

The protein tyrosine phosphatase TCPTP suppresses the tumorigenicity of glioblastoma cells expressing a mutant epidermal growth factor receptor.

Klingler-Hoffmann M, Fodero-Tavoletti MT, Mishima K, Narita Y, Cavenee WK, Furnari FB, Huang HJ, Tiganis T.

J Biol Chem. 2001 Dec 7;276(49):46313-8.

3.

The protein tyrosine phosphatase TCPTP controls VEGFR2 signalling.

Mattila E, Auvinen K, Salmi M, Ivaska J.

J Cell Sci. 2008 Nov 1;121(Pt 21):3570-80. doi: 10.1242/jcs.031898. Epub 2008 Oct 7.

4.

Epidermal growth factor receptor-dependent regulation of integrin-mediated signaling and cell cycle entry in epithelial cells.

Bill HM, Knudsen B, Moores SL, Muthuswamy SK, Rao VR, Brugge JS, Miranti CK.

Mol Cell Biol. 2004 Oct;24(19):8586-99.

5.

EGFR activation coupled to inhibition of tyrosine phosphatases causes lateral signal propagation.

Reynolds AR, Tischer C, Verveer PJ, Rocks O, Bastiaens PI.

Nat Cell Biol. 2003 May;5(5):447-53.

PMID:
12717446
6.

Receptor-type protein-tyrosine phosphatase-kappa regulates epidermal growth factor receptor function.

Xu Y, Tan LJ, Grachtchouk V, Voorhees JJ, Fisher GJ.

J Biol Chem. 2005 Dec 30;280(52):42694-700. Epub 2005 Oct 31.

7.

P130Cas-associated protein (p140Cap) as a new tyrosine-phosphorylated protein involved in cell spreading.

Di Stefano P, Cabodi S, Boeri Erba E, Margaria V, Bergatto E, Giuffrida MG, Silengo L, Tarone G, Turco E, Defilippi P.

Mol Biol Cell. 2004 Feb;15(2):787-800. Epub 2003 Dec 2.

8.

Inhibition of receptor tyrosine kinase signalling by small molecule agonist of T-cell protein tyrosine phosphatase.

Mattila E, Marttila H, Sahlberg N, Kohonen P, Tähtinen S, Halonen P, Perälä M, Ivaska J.

BMC Cancer. 2010 Jan 7;10:7. doi: 10.1186/1471-2407-10-7.

9.

Unique role of SNT-2/FRS2beta/FRS3 docking/adaptor protein for negative regulation in EGF receptor tyrosine kinase signaling pathways.

Huang L, Watanabe M, Chikamori M, Kido Y, Yamamoto T, Shibuya M, Gotoh N, Tsuchida N.

Oncogene. 2006 Oct 19;25(49):6457-66. Epub 2006 May 15.

PMID:
16702953
10.
12.

Phospholipase Cgamma1 negatively regulates growth hormone signalling by forming a ternary complex with Jak2 and protein tyrosine phosphatase-1B.

Choi JH, Kim HS, Kim SH, Yang YR, Bae YS, Chang JS, Kwon HM, Ryu SH, Suh PG.

Nat Cell Biol. 2006 Dec;8(12):1389-97. Epub 2006 Nov 26.

PMID:
17128263
13.

Crosstalk between androgen receptor and epidermal growth factor receptor-signalling pathways: a molecular switch for epithelial cell differentiation.

Léotoing L, Manin M, Monté D, Baron S, Communal Y, Lours C, Veyssière G, Morel L, Beaudoin C.

J Mol Endocrinol. 2007 Aug;39(2):151-62.

PMID:
17693613
14.

Integrin regulation of epidermal growth factor (EGF) receptor and of EGF-dependent responses.

Cabodi S, Moro L, Bergatto E, Boeri Erba E, Di Stefano P, Turco E, Tarone G, Defilippi P.

Biochem Soc Trans. 2004 Jun;32(Pt3):438-42. Review.

PMID:
15157155
16.

Inhibition of heat shock protein 90 impairs epidermal growth factor-mediated signaling in gastric cancer cells and reduces tumor growth and vascularization in vivo.

Lang SA, Klein D, Moser C, Gaumann A, Glockzin G, Dahlke MH, Dietmaier W, Bolder U, Schlitt HJ, Geissler EK, Stoeltzing O.

Mol Cancer Ther. 2007 Mar;6(3):1123-32.

17.

Integrin {alpha}1{beta}1 promotes caveolin-1 dephosphorylation by activating T cell protein-tyrosine phosphatase.

Borza CM, Chen X, Mathew S, Mont S, Sanders CR, Zent R, Pozzi A.

J Biol Chem. 2010 Dec 17;285(51):40114-24. doi: 10.1074/jbc.M110.156729. Epub 2010 Oct 12.

19.
20.

Beta4 integrin activates a Shp2-Src signaling pathway that sustains HGF-induced anchorage-independent growth.

Bertotti A, Comoglio PM, Trusolino L.

J Cell Biol. 2006 Dec 18;175(6):993-1003. Epub 2006 Dec 11.

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