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Items: 1 to 20 of 113

1.

Nav1.5 E1053K mutation causing Brugada syndrome blocks binding to ankyrin-G and expression of Nav1.5 on the surface of cardiomyocytes.

Mohler PJ, Rivolta I, Napolitano C, LeMaillet G, Lambert S, Priori SG, Bennett V.

Proc Natl Acad Sci U S A. 2004 Dec 14;101(50):17533-8.

2.

Voltage-gated Nav channel targeting in the heart requires an ankyrin-G dependent cellular pathway.

Lowe JS, Palygin O, Bhasin N, Hund TJ, Boyden PA, Shibata E, Anderson ME, Mohler PJ.

J Cell Biol. 2008 Jan 14;180(1):173-86. doi: 10.1083/jcb.200710107.

3.

Being there: cellular targeting of voltage-gated sodium channels in the heart.

Bennett V, Healy J.

J Cell Biol. 2008 Jan 14;180(1):13-5. doi: 10.1083/jcb.200712098.

4.

Ankyrin-G coordinates intercalated disc signaling platform to regulate cardiac excitability in vivo.

Makara MA, Curran J, Little SC, Musa H, Polina I, Smith SA, Wright PJ, Unudurthi SD, Snyder J, Bennett V, Hund TJ, Mohler PJ.

Circ Res. 2014 Nov 7;115(11):929-38. doi: 10.1161/CIRCRESAHA.115.305154.

5.

Ankyrin-based cardiac arrhythmias: a new class of channelopathies due to loss of cellular targeting.

Mohler PJ, Bennett V.

Curr Opin Cardiol. 2005 May;20(3):189-93. Review.

PMID:
15861006
6.

SAP97 and dystrophin macromolecular complexes determine two pools of cardiac sodium channels Nav1.5 in cardiomyocytes.

Petitprez S, Zmoos AF, Ogrodnik J, Balse E, Raad N, El-Haou S, Albesa M, Bittihn P, Luther S, Lehnart SE, Hatem SN, Coulombe A, Abriel H.

Circ Res. 2011 Feb 4;108(3):294-304. doi: 10.1161/CIRCRESAHA.110.228312.

7.
8.

Ca2+/calmodulin-dependent protein kinase II (CaMKII) regulates cardiac sodium channel NaV1.5 gating by multiple phosphorylation sites.

Ashpole NM, Herren AW, Ginsburg KS, Brogan JD, Johnson DE, Cummins TR, Bers DM, Hudmon A.

J Biol Chem. 2012 Jun 8;287(24):19856-69. doi: 10.1074/jbc.M111.322537.

9.

Cardiac voltage-gated sodium channel Nav1.5 is regulated by Nedd4-2 mediated ubiquitination.

van Bemmelen MX, Rougier JS, Gavillet B, Apothéloz F, Daidié D, Tateyama M, Rivolta I, Thomas MA, Kass RS, Staub O, Abriel H.

Circ Res. 2004 Aug 6;95(3):284-91.

10.

A mutation in telethonin alters Nav1.5 function.

Mazzone A, Strege PR, Tester DJ, Bernard CE, Faulkner G, De Giorgio R, Makielski JC, Stanghellini V, Gibbons SJ, Ackerman MJ, Farrugia G.

J Biol Chem. 2008 Jun 13;283(24):16537-44. doi: 10.1074/jbc.M801744200. Erratum in: J Biol Chem. 2008 Aug 8;283(32):22336.

11.

Protein kinase CK2 contributes to the organization of sodium channels in axonal membranes by regulating their interactions with ankyrin G.

Bréchet A, Fache MP, Brachet A, Ferracci G, Baude A, Irondelle M, Pereira S, Leterrier C, Dargent B.

J Cell Biol. 2008 Dec 15;183(6):1101-14. doi: 10.1083/jcb.200805169.

12.

Functional Interactions between Distinct Sodium Channel Cytoplasmic Domains through the Action of Calmodulin.

Potet F, Chagot B, Anghelescu M, Viswanathan PC, Stepanovic SZ, Kupershmidt S, Chazin WJ, Balser JR.

J Biol Chem. 2009 Mar 27;284(13):8846-54. doi: 10.1074/jbc.M806871200.

13.

Ankyrin-G participates in INa remodeling in myocytes from the border zones of infarcted canine heart.

Dun W, Lowe JS, Wright P, Hund TJ, Mohler PJ, Boyden PA.

PLoS One. 2013 Oct 14;8(10):e78087. doi: 10.1371/journal.pone.0078087.

14.

Cardiac Na+ current regulation by pyridine nucleotides.

Liu M, Sanyal S, Gao G, Gurung IS, Zhu X, Gaconnet G, Kerchner LJ, Shang LL, Huang CL, Grace A, London B, Dudley SC Jr.

Circ Res. 2009 Oct 9;105(8):737-45. doi: 10.1161/CIRCRESAHA.109.197277.

15.

Regulation of the voltage-gated cardiac sodium channel Nav1.5 by interacting proteins.

Abriel H, Kass RS.

Trends Cardiovasc Med. 2005 Jan;15(1):35-40. Review.

PMID:
15795161
16.

Calcium-dependent regulation of the voltage-gated sodium channel hH1: intrinsic and extrinsic sensors use a common molecular switch.

Shah VN, Wingo TL, Weiss KL, Williams CK, Balser JR, Chazin WJ.

Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3592-7.

17.

Voltage-gated sodium channel modulation by sigma-receptors in cardiac myocytes and heterologous systems.

Johannessen M, Ramachandran S, Riemer L, Ramos-Serrano A, Ruoho AE, Jackson MB.

Am J Physiol Cell Physiol. 2009 May;296(5):C1049-57. doi: 10.1152/ajpcell.00431.2008.

18.

Obscurin targets ankyrin-B and protein phosphatase 2A to the cardiac M-line.

Cunha SR, Mohler PJ.

J Biol Chem. 2008 Nov 14;283(46):31968-80. doi: 10.1074/jbc.M806050200.

19.

Immunohistochemical marker for Na+ CP type Valpha (C-20) and heterozygous nonsense SCN5A mutation W822X in a sudden cardiac death induced by mild anaphylactic reaction.

Turillazzi E, Pomara C, La Rocca G, Neri M, Riezzo I, Karch SB, Anzalone R, Lo Iacono M, Fineschi V.

Appl Immunohistochem Mol Morphol. 2009 Jul;17(4):357-62. doi: 10.1097/PAI.0b013e3181955b37.

PMID:
19318916
20.
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