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Bone marrow-derived cells contribute to contractile dysfunction in endotoxic shock.

Binck BW, Tsen MF, Islas M, White DJ, Schultz RA, Willis MS, Garcia JV, Horton JW, Thomas JA.

Am J Physiol Heart Circ Physiol. 2005 Feb;288(2):H577-83.


Cardiomyocyte Toll-like receptor 4 is involved in heart dysfunction following septic shock or myocardial ischemia.

Fallach R, Shainberg A, Avlas O, Fainblut M, Chepurko Y, Porat E, Hochhauser E.

J Mol Cell Cardiol. 2010 Jun;48(6):1236-44. doi: 10.1016/j.yjmcc.2010.02.020.


TLR4 inactivation and rBPI(21) block burn-induced myocardial contractile dysfunction.

Thomas JA, Tsen MF, White DJ, Horton JW.

Am J Physiol Heart Circ Physiol. 2002 Oct;283(4):H1645-55.


Endothelium-derived Toll-like receptor-4 is the key molecule in LPS-induced neutrophil sequestration into lungs.

Andonegui G, Bonder CS, Green F, Mullaly SC, Zbytnuik L, Raharjo E, Kubes P.

J Clin Invest. 2003 Apr;111(7):1011-20. Erratum in: J Clin Invest. 2003 Oct;112(8):1264.


IRAK1 deletion disrupts cardiac Toll/IL-1 signaling and protects against contractile dysfunction.

Thomas JA, Haudek SB, Koroglu T, Tsen MF, Bryant DD, White DJ, Kusewitt DF, Horton JW, Giroir BP.

Am J Physiol Heart Circ Physiol. 2003 Aug;285(2):H597-606. Erratum in: Am J Physiol Heart Circ Physiol. 2004 Jan;286(1):H477.


Genes other than TLR4 are involved in the response to inhaled LPS.

Lorenz E, Jones M, Wohlford-Lenane C, Meyer N, Frees KL, Arbour NC, Schwartz DA.

Am J Physiol Lung Cell Mol Physiol. 2001 Nov;281(5):L1106-14.


Signaling for myocardial depression in hemorrhagic shock: roles of Toll-like receptor 4 and p55 TNF-alpha receptor.

Meng X, Ao L, Song Y, Raeburn CD, Fullerton DA, Harken AH.

Am J Physiol Regul Integr Comp Physiol. 2005 Mar;288(3):R600-6.


Immune cell Toll-like receptor 4 is required for cardiac myocyte impairment during endotoxemia.

Tavener SA, Long EM, Robbins SM, McRae KM, Van Remmen H, Kubes P.

Circ Res. 2004 Oct 1;95(7):700-7.


Role for CD14, TLR2, and TLR4 in bacterial product-induced anorexia.

von Meyenburg C, Hrupka BH, Arsenijevic D, Schwartz GJ, Landmann R, Langhans W.

Am J Physiol Regul Integr Comp Physiol. 2004 Aug;287(2):R298-305.


Toll-like receptor 4 involvement in hepatic ischemia/reperfusion injury in mice.

Wu HS, Zhang JX, Wang L, Tian Y, Wang H, Rotstein O.

Hepatobiliary Pancreat Dis Int. 2004 May;3(2):250-3.


LPS activation of Toll-like receptor 4 signals CD11b/CD18 expression in neutrophils.

Zhou X, Gao XP, Fan J, Liu Q, Anwar KN, Frey RS, Malik AB.

Am J Physiol Lung Cell Mol Physiol. 2005 Apr;288(4):L655-62.


Endotoxin-mimetic effect of antibodies against Toll-like receptor 4.

Nattermann J, Du X, Wei Y, Shevchenko D, Beutler B.

J Endotoxin Res. 2000;6(3):257-64.


Reduced myocardial ischemia-reperfusion injury in toll-like receptor 4-deficient mice.

Oyama J, Blais C Jr, Liu X, Pu M, Kobzik L, Kelly RA, Bourcier T.

Circulation. 2004 Feb 17;109(6):784-9.


IL-10 and toll-like receptor-4 polymorphisms and the in vivo and ex vivo response to endotoxin.

Schippers EF, van 't Veer C, van Voorden S, Martina CA, Huizinga TW, le Cessie S, van Dissel JT.

Cytokine. 2005 Mar 7;29(5):215-28.


Escherichia coli LPS-induced LV dysfunction: role of toll-like receptor-4 in the adult heart.

Nemoto S, Vallejo JG, Knuefermann P, Misra A, Defreitas G, Carabello BA, Mann DL.

Am J Physiol Heart Circ Physiol. 2002 Jun;282(6):H2316-23.


Role of endothelial TLR4 for neutrophil recruitment into central nervous system microvessels in systemic inflammation.

Zhou H, Andonegui G, Wong CH, Kubes P.

J Immunol. 2009 Oct 15;183(8):5244-50. doi: 10.4049/jimmunol.0901309.


Toll-like receptor 4 stimulation initiates an inflammatory response that decreases cardiomyocyte contractility.

Avlas O, Fallach R, Shainberg A, Porat E, Hochhauser E.

Antioxid Redox Signal. 2011 Oct 1;15(7):1895-909. doi: 10.1089/ars.2010.3728. Review.


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