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Items: 1 to 20 of 90

1.

XBP1 is essential for survival under hypoxic conditions and is required for tumor growth.

Romero-Ramirez L, Cao H, Nelson D, Hammond E, Lee AH, Yoshida H, Mori K, Glimcher LH, Denko NC, Giaccia AJ, Le QT, Koong AC.

Cancer Res. 2004 Sep 1;64(17):5943-7.

2.

Hypoxia-inducible factor-1alpha is a positive factor in solid tumor growth.

Ryan HE, Poloni M, McNulty W, Elson D, Gassmann M, Arbeit JM, Johnson RS.

Cancer Res. 2000 Aug 1;60(15):4010-5.

3.

Human X-box binding protein-1 confers both estrogen independence and antiestrogen resistance in breast cancer cell lines.

Gomez BP, Riggins RB, Shajahan AN, Klimach U, Wang A, Crawford AC, Zhu Y, Zwart A, Wang M, Clarke R.

FASEB J. 2007 Dec;21(14):4013-27. Epub 2007 Jul 27.

PMID:
17660348
5.

Analysis of hypoxia-related gene expression in sarcomas and effect of hypoxia on RNA interference of vascular endothelial cell growth factor A.

Detwiller KY, Fernando NT, Segal NH, Ryeom SW, D'Amore PA, Yoon SS.

Cancer Res. 2005 Jul 1;65(13):5881-9.

6.

Preventing oxidative stress: a new role for XBP1.

Liu Y, Adachi M, Zhao S, Hareyama M, Koong AC, Luo D, Rando TA, Imai K, Shinomura Y.

Cell Death Differ. 2009 Jun;16(6):847-57. doi: 10.1038/cdd.2009.14. Epub 2009 Feb 27.

7.

IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response.

Lee K, Tirasophon W, Shen X, Michalak M, Prywes R, Okada T, Yoshida H, Mori K, Kaufman RJ.

Genes Dev. 2002 Feb 15;16(4):452-66.

8.

Cytoplasmic IRE1alpha-mediated XBP1 mRNA splicing in the absence of nuclear processing and endoplasmic reticulum stress.

Back SH, Lee K, Vink E, Kaufman RJ.

J Biol Chem. 2006 Jul 7;281(27):18691-706. Epub 2006 Apr 27.

9.
10.

Anoxia is necessary for tumor cell toxicity caused by a low-oxygen environment.

Papandreou I, Krishna C, Kaper F, Cai D, Giaccia AJ, Denko NC.

Cancer Res. 2005 Apr 15;65(8):3171-8.

11.

Activation of the unfolded protein response in infarcted mouse heart and hypoxic cultured cardiac myocytes.

Thuerauf DJ, Marcinko M, Gude N, Rubio M, Sussman MA, Glembotski CC.

Circ Res. 2006 Aug 4;99(3):275-82. Epub 2006 Jun 22.

12.

Upregulated ROS production induced by the proteasome inhibitor MG-132 on XBP1 gene expression and cell apoptosis in Tca-8113 cells.

Chen HY, Ren XY, Wang WH, Zhang YX, Chen SF, Zhang B, Wang LX.

Biomed Pharmacother. 2014 Jul;68(6):709-13. doi: 10.1016/j.biopha.2014.07.011. Epub 2014 Jul 18.

PMID:
25092240
13.

XBP1 mRNA splicing triggers an autophagic response in endothelial cells through BECLIN-1 transcriptional activation.

Margariti A, Li H, Chen T, Martin D, Vizcay-Barrena G, Alam S, Karamariti E, Xiao Q, Zampetaki A, Zhang Z, Wang W, Jiang Z, Gao C, Ma B, Chen YG, Cockerill G, Hu Y, Xu Q, Zeng L.

J Biol Chem. 2013 Jan 11;288(2):859-72. doi: 10.1074/jbc.M112.412783. Epub 2012 Nov 26.

14.
15.

Activation of the ATF6, XBP1 and grp78 genes in human hepatocellular carcinoma: a possible involvement of the ER stress pathway in hepatocarcinogenesis.

Shuda M, Kondoh N, Imazeki N, Tanaka K, Okada T, Mori K, Hada A, Arai M, Wakatsuki T, Matsubara O, Yamamoto N, Yamamoto M.

J Hepatol. 2003 May;38(5):605-14.

PMID:
12713871
16.

ER stress signaling by regulated splicing: IRE1/HAC1/XBP1.

Back SH, Schröder M, Lee K, Zhang K, Kaufman RJ.

Methods. 2005 Apr;35(4):395-416.

PMID:
15804613
17.

XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum.

Sriburi R, Jackowski S, Mori K, Brewer JW.

J Cell Biol. 2004 Oct 11;167(1):35-41. Epub 2004 Oct 4.

18.
19.

HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors.

Sowter HM, Ratcliffe PJ, Watson P, Greenberg AH, Harris AL.

Cancer Res. 2001 Sep 15;61(18):6669-73.

20.

The human trithorax protein hASH2 functions as an oncoprotein.

Lüscher-Firzlaff J, Gawlista I, Vervoorts J, Kapelle K, Braunschweig T, Walsemann G, Rodgarkia-Schamberger C, Schuchlautz H, Dreschers S, Kremmer E, Lilischkis R, Cerni C, Wellmann A, Lüscher B.

Cancer Res. 2008 Feb 1;68(3):749-58. doi: 10.1158/0008-5472.CAN-07-3158.

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