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Items: 1 to 20 of 154

1.

Impaired glucose homeostasis in transgenic mice expressing the human transient neonatal diabetes mellitus locus, TNDM.

Ma D, Shield JP, Dean W, Leclerc I, Knauf C, Burcelin R Ré, Rutter GA, Kelsey G.

J Clin Invest. 2004 Aug;114(3):339-48.

2.

Overexpression of a dominant negative GIP receptor in transgenic mice results in disturbed postnatal pancreatic islet and beta-cell development.

Herbach N, Goeke B, Schneider M, Hermanns W, Wolf E, Wanke R.

Regul Pept. 2005 Feb 15;125(1-3):103-17.

PMID:
15582721
3.
4.

beta-cell glucokinase deficiency and hyperglycemia are associated with reduced islet amyloid deposition in a mouse model of type 2 diabetes.

Andrikopoulos S, Verchere CB, Terauchi Y, Kadowaki T, Kahn SE.

Diabetes. 2000 Dec;49(12):2056-62.

PMID:
11118007
5.

Early diabetes and abnormal postnatal pancreatic islet development in mice lacking Glut-2.

Guillam MT, Hümmler E, Schaerer E, Yeh JI, Birnbaum MJ, Beermann F, Schmidt A, Dériaz N, Thorens B.

Nat Genet. 1997 Nov;17(3):327-30. Erratum in: Nat Genet 1997 Dec;17(4):503. Wu JY [corrected to Yeh JI].

PMID:
9354799
6.

Overexpression of c-Myc in beta-cells of transgenic mice causes proliferation and apoptosis, downregulation of insulin gene expression, and diabetes.

Laybutt DR, Weir GC, Kaneto H, Lebet J, Palmiter RD, Sharma A, Bonner-Weir S.

Diabetes. 2002 Jun;51(6):1793-804.

7.

Huntington's disease of the endocrine pancreas: insulin deficiency and diabetes mellitus due to impaired insulin gene expression.

Andreassen OA, Dedeoglu A, Stanojevic V, Hughes DB, Browne SE, Leech CA, Ferrante RJ, Habener JF, Beal MF, Thomas MK.

Neurobiol Dis. 2002 Dec;11(3):410-24.

PMID:
12586550
8.

Relaxation of imprinted expression of ZAC and HYMAI in a patient with transient neonatal diabetes mellitus.

Mackay DJ, Coupe AM, Shield JP, Storr JN, Temple IK, Robinson DO.

Hum Genet. 2002 Feb;110(2):139-44. Epub 2002 Jan 24.

PMID:
11935319
9.

A conserved imprinting control region at the HYMAI/ZAC domain is implicated in transient neonatal diabetes mellitus.

Arima T, Drewell RA, Arney KL, Inoue J, Makita Y, Hata A, Oshimura M, Wake N, Surani MA.

Hum Mol Genet. 2001 Jul 1;10(14):1475-83.

PMID:
11448939
10.

A novel imprinted gene, HYMAI, is located within an imprinted domain on human chromosome 6 containing ZAC.

Arima T, Drewell RA, Oshimura M, Wake N, Surani MA.

Genomics. 2000 Aug 1;67(3):248-55.

PMID:
10936046
11.

The HNF-1 target collectrin controls insulin exocytosis by SNARE complex formation.

Fukui K, Yang Q, Cao Y, Takahashi N, Hatakeyama H, Wang H, Wada J, Zhang Y, Marselli L, Nammo T, Yoneda K, Onishi M, Higashiyama S, Matsuzawa Y, Gonzalez FJ, Weir GC, Kasai H, Shimomura I, Miyagawa J, Wollheim CB, Yamagata K.

Cell Metab. 2005 Dec;2(6):373-84.

12.

Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKB beta.

Garofalo RS, Orena SJ, Rafidi K, Torchia AJ, Stock JL, Hildebrandt AL, Coskran T, Black SC, Brees DJ, Wicks JR, McNeish JD, Coleman KG.

J Clin Invest. 2003 Jul;112(2):197-208. Epub 2003 Jul 3.

13.

Impaired pancreatic beta cell function in the fetal GK rat. Impact of diabetic inheritance.

Serradas P, Gangnerau MN, Giroix MH, Saulnier C, Portha B.

J Clin Invest. 1998 Feb 15;101(4):899-904.

14.

A general and islet cell-enriched overexpression of IGF-I results in normal islet cell growth, hypoglycemia, and significant resistance to experimental diabetes.

Robertson K, Lu Y, De Jesus K, Li B, Su Q, Lund PK, Liu JL.

Am J Physiol Endocrinol Metab. 2008 May;294(5):E928-38. doi: 10.1152/ajpendo.00606.2007. Epub 2008 Feb 12.

15.
16.

Transgenic mice overexpressing alpha2A-adrenoceptors in pancreatic beta-cells show altered regulation of glucose homeostasis.

Devedjian JC, Pujol A, Cayla C, George M, Casellas A, Paris H, Bosch F.

Diabetologia. 2000 Jul;43(7):899-906.

PMID:
10952463
17.

Evidence from transgenic mice that interferon-beta may be involved in the onset of diabetes mellitus.

Pelegrin M, Devedjian JC, Costa C, Visa J, Solanes G, Pujol A, Asins G, Valera A, Bosch F.

J Biol Chem. 1998 May 15;273(20):12332-40.

18.

Assessment of the role of common genetic variation in the transient neonatal diabetes mellitus (TNDM) region in type 2 diabetes: a comparative genomic and tagging single nucleotide polymorphism approach.

Gloyn AL, Mackay DJ, Weedon MN, McCarthy MI, Walker M, Hitman G, Knight BA, Owen KR, Hattersley AT, Frayling TM.

Diabetes. 2006 Aug;55(8):2272-6.

19.

Cell-specific roles of glucokinase in glucose homeostasis.

Postic C, Shiota M, Magnuson MA.

Recent Prog Horm Res. 2001;56:195-217. Review.

PMID:
11237213
20.

Calmodulin-induced early-onset diabetes in transgenic mice.

Epstein PN, Overbeek PA, Means AR.

Cell. 1989 Sep 22;58(6):1067-73.

PMID:
2673540

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