Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 97

1.

Pim-1 kinase promotes inactivation of the pro-apoptotic Bad protein by phosphorylating it on the Ser112 gatekeeper site.

Aho TL, Sandholm J, Peltola KJ, Mankonen HP, Lilly M, Koskinen PJ.

FEBS Lett. 2004 Jul 30;571(1-3):43-9.

2.

The PIM-2 kinase phosphorylates BAD on serine 112 and reverses BAD-induced cell death.

Yan B, Zemskova M, Holder S, Chin V, Kraft A, Koskinen PJ, Lilly M.

J Biol Chem. 2003 Nov 14;278(46):45358-67. Epub 2003 Sep 3.

3.

Identification of a novel phosphorylation site, Ser-170, as a regulator of bad pro-apoptotic activity.

Dramsi S, Scheid MP, Maiti A, Hojabrpour P, Chen X, Schubert K, Goodlett DR, Aebersold R, Duronio V.

J Biol Chem. 2002 Feb 22;277(8):6399-405. Epub 2001 Nov 20.

4.
5.
6.

Interleukin-7 inactivates the pro-apoptotic protein Bad promoting T cell survival.

Li WQ, Jiang Q, Khaled AR, Keller JR, Durum SK.

J Biol Chem. 2004 Jul 9;279(28):29160-6. Epub 2004 Apr 30.

7.
8.

Serine/threonine kinase Pim-2 promotes liver tumorigenesis induction through mediating survival and preventing apoptosis of liver cell.

Gong J, Wang J, Ren K, Liu C, Li B, Shi Y.

J Surg Res. 2009 May 1;153(1):17-22. doi: 10.1016/j.jss.2008.03.033. Epub 2008 Apr 22.

PMID:
18675992
9.

Growth factors inactivate the cell death promoter BAD by phosphorylation of its BH3 domain on Ser155.

Zhou XM, Liu Y, Payne G, Lutz RJ, Chittenden T.

J Biol Chem. 2000 Aug 11;275(32):25046-51.

10.

Proto-oncogene, Pim-3 with serine/threonine kinase activity, is aberrantly expressed in human colon cancer cells and can prevent Bad-mediated apoptosis.

Popivanova BK, Li YY, Zheng H, Omura K, Fujii C, Tsuneyama K, Mukaida N.

Cancer Sci. 2007 Mar;98(3):321-8.

12.

Constitutively activated FLT3 phosphorylates BAD partially through pim-1.

Kim KT, Levis M, Small D.

Br J Haematol. 2006 Sep;134(5):500-9.

PMID:
16869825
13.

Pim kinases phosphorylate multiple sites on Bad and promote 14-3-3 binding and dissociation from Bcl-XL.

Macdonald A, Campbell DG, Toth R, McLauchlan H, Hastie CJ, Arthur JS.

BMC Cell Biol. 2006 Jan 10;7:1.

14.

The oncogenic serine/threonine kinase Pim-1 directly phosphorylates and activates the G2/M specific phosphatase Cdc25C.

Bachmann M, Kosan C, Xing PX, Montenarh M, Hoffmann I, Möröy T.

Int J Biochem Cell Biol. 2006 Mar;38(3):430-43. Epub 2005 Nov 8.

PMID:
16356754
15.

Protein phosphatase 2A regulates apoptosis in intestinal epithelial cells.

Ray RM, Bhattacharya S, Johnson LR.

J Biol Chem. 2005 Sep 2;280(35):31091-100. Epub 2005 Jul 1.

16.

Pim-1 associates with protein complexes necessary for mitosis.

Bhattacharya N, Wang Z, Davitt C, McKenzie IF, Xing PX, Magnuson NS.

Chromosoma. 2002 Jul;111(2):80-95. Epub 2002 May 15.

PMID:
12111331
17.

Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway.

Yano S, Tokumitsu H, Soderling TR.

Nature. 1998 Dec 10;396(6711):584-7.

PMID:
9859994
18.

Recombinant human pim-1 protein exhibits serine/threonine kinase activity.

Hoover D, Friedmann M, Reeves R, Magnuson NS.

J Biol Chem. 1991 Jul 25;266(21):14018-23.

19.
20.

Supplemental Content

Support Center