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Items: 1 to 20 of 290

1.

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling.

Wertz IE, O'Rourke KM, Zhou H, Eby M, Aravind L, Seshagiri S, Wu P, Wiesmann C, Baker R, Boone DL, Ma A, Koonin EV, Dixit VM.

Nature. 2004 Aug 5;430(7000):694-9.

PMID:
15258597
2.

Inhibition of NF-kappaB signaling by A20 through disruption of ubiquitin enzyme complexes.

Shembade N, Ma A, Harhaj EW.

Science. 2010 Feb 26;327(5969):1135-9. doi: 10.1126/science.1182364.

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The ubiquitin-editing enzyme A20 requires RNF11 to downregulate NF-kappaB signalling.

Shembade N, Parvatiyar K, Harhaj NS, Harhaj EW.

EMBO J. 2009 Mar 4;28(5):513-22. doi: 10.1038/emboj.2008.285.

5.

Molecular basis for the unique deubiquitinating activity of the NF-kappaB inhibitor A20.

Lin SC, Chung JY, Lamothe B, Rajashankar K, Lu M, Lo YC, Lam AY, Darnay BG, Wu H.

J Mol Biol. 2008 Feb 15;376(2):526-40. doi: 10.1016/j.jmb.2007.11.092.

6.

Negative regulation of the retinoic acid-inducible gene I-induced antiviral state by the ubiquitin-editing protein A20.

Lin R, Yang L, Nakhaei P, Sun Q, Sharif-Askari E, Julkunen I, Hiscott J.

J Biol Chem. 2006 Jan 27;281(4):2095-103.

7.

A20 inhibits NF-kappaB activation by dual ubiquitin-editing functions.

Heyninck K, Beyaert R.

Trends Biochem Sci. 2005 Jan;30(1):1-4. Review.

PMID:
15653317
8.

A20 negatively regulates T cell receptor signaling to NF-kappaB by cleaving Malt1 ubiquitin chains.

Düwel M, Welteke V, Oeckinghaus A, Baens M, Kloo B, Ferch U, Darnay BG, Ruland J, Marynen P, Krappmann D.

J Immunol. 2009 Jun 15;182(12):7718-28. doi: 10.4049/jimmunol.0803313.

9.

Ubiquitin binding to A20 ZnF4 is required for modulation of NF-κB signaling.

Bosanac I, Wertz IE, Pan B, Yu C, Kusam S, Lam C, Phu L, Phung Q, Maurer B, Arnott D, Kirkpatrick DS, Dixit VM, Hymowitz SG.

Mol Cell. 2010 Nov 24;40(4):548-57. doi: 10.1016/j.molcel.2010.10.009.

10.

Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2.

Alvarez SE, Harikumar KB, Hait NC, Allegood J, Strub GM, Kim EY, Maceyka M, Jiang H, Luo C, Kordula T, Milstien S, Spiegel S.

Nature. 2010 Jun 24;465(7301):1084-8. doi: 10.1038/nature09128.

11.

Identification of a novel A20-binding inhibitor of nuclear factor-kappa B activation termed ABIN-2.

Van Huffel S, Delaei F, Heyninck K, De Valck D, Beyaert R.

J Biol Chem. 2001 Aug 10;276(32):30216-23.

12.

ABIN-1 binds to NEMO/IKKgamma and co-operates with A20 in inhibiting NF-kappaB.

Mauro C, Pacifico F, Lavorgna A, Mellone S, Iannetti A, Acquaviva R, Formisano S, Vito P, Leonardi A.

J Biol Chem. 2006 Jul 7;281(27):18482-8.

13.

Downstream activation of NF-κB in the EDA-A1/EDAR signalling in Sjögren's syndrome and its regulation by the ubiquitin-editing enzyme A20.

Sisto M, Barca A, Lofrumento DD, Lisi S.

Clin Exp Immunol. 2016 May;184(2):183-96. doi: 10.1111/cei.12764.

PMID:
26724675
14.

Emergence of the A20/ABIN-mediated inhibition of NF-κB signaling via modifying the ubiquitinated proteins in a basal chordate.

Yuan S, Dong X, Tao X, Xu L, Ruan J, Peng J, Xu A.

Proc Natl Acad Sci U S A. 2014 May 6;111(18):6720-5. doi: 10.1073/pnas.1321187111.

15.

Zinc-finger protein A20, a regulator of inflammation and cell survival, has de-ubiquitinating activity.

Evans PC, Ovaa H, Hamon M, Kilshaw PJ, Hamm S, Bauer S, Ploegh HL, Smith TS.

Biochem J. 2004 Mar 15;378(Pt 3):727-34.

16.

Ubiquitin-associated domain-containing ubiquitin regulatory X (UBX) protein UBXN1 is a negative regulator of nuclear factor κB (NF-κB) signaling.

Wang YB, Tan B, Mu R, Chang Y, Wu M, Tu HQ, Zhang YC, Guo SS, Qin XH, Li T, Li WH, Li AL, Zhang XM, Li HY.

J Biol Chem. 2015 Apr 17;290(16):10395-405. doi: 10.1074/jbc.M114.631689.

17.

Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-κB regulation.

Tokunaga F, Nishimasu H, Ishitani R, Goto E, Noguchi T, Mio K, Kamei K, Ma A, Iwai K, Nureki O.

EMBO J. 2012 Oct 3;31(19):3856-70. doi: 10.1038/emboj.2012.241.

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NF-kappaB suppression by the deubiquitinating enzyme Cezanne: a novel negative feedback loop in pro-inflammatory signaling.

Enesa K, Zakkar M, Chaudhury H, Luong le A, Rawlinson L, Mason JC, Haskard DO, Dean JL, Evans PC.

J Biol Chem. 2008 Mar 14;283(11):7036-45. doi: 10.1074/jbc.M708690200.

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