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Items: 1 to 20 of 93

1.

The Hedgehog response network: sensors, switches, and routers.

Lum L, Beachy PA.

Science. 2004 Jun 18;304(5678):1755-9. Review.

PMID:
15205520
2.

Regulation of Hedgehog signaling: a complex story.

Ogden SK, Ascano M Jr, Stegman MA, Robbins DJ.

Biochem Pharmacol. 2004 Mar 1;67(5):805-14. Review.

3.

Hedgehog signal transduction via Smoothened association with a cytoplasmic complex scaffolded by the atypical kinesin, Costal-2.

Lum L, Zhang C, Oh S, Mann RK, von Kessler DP, Taipale J, Weis-Garcia F, Gong R, Wang B, Beachy PA.

Mol Cell. 2003 Nov;12(5):1261-74.

4.

Hedgehog signalling: off the shelf modulation.

van den Heuvel M.

Curr Biol. 2003 Sep 2;13(17):R686-8. Review.

5.

PP4 and PP2A regulate Hedgehog signaling by controlling Smo and Ci phosphorylation.

Jia H, Liu Y, Yan W, Jia J.

Development. 2009 Jan;136(2):307-16. doi: 10.1242/dev.030015. Epub 2008 Dec 15.

6.

Hedgehog signaling: Costal-2 bridges the transduction gap.

Kalderon D.

Curr Biol. 2004 Jan 20;14(2):R67-9. Review.

7.

Phosphorylation of the atypical kinesin Costal2 by the kinase Fused induces the partial disassembly of the Smoothened-Fused-Costal2-Cubitus interruptus complex in Hedgehog signalling.

Ruel L, Gallet A, Raisin S, Truchi A, Staccini-Lavenant L, Cervantes A, Thérond PP.

Development. 2007 Oct;134(20):3677-89. Epub 2007 Sep 19.

8.

Smoothened regulates activator and repressor functions of Hedgehog signaling via two distinct mechanisms.

Ogden SK, Casso DJ, Ascano M Jr, Yore MM, Kornberg TB, Robbins DJ.

J Biol Chem. 2006 Mar 17;281(11):7237-43. Epub 2006 Jan 19.

9.

Phosphorylation regulation of Hedgehog signaling.

Jia J.

Vitam Horm. 2012;88:253-72. doi: 10.1016/B978-0-12-394622-5.00011-0. Review.

PMID:
22391307
10.

The mechanism of hedgehog signal transduction.

Kalderon D.

Biochem Soc Trans. 2005 Dec;33(Pt 6):1509-12. Review.

PMID:
16246157
11.

Switch of PKA substrates from Cubitus interruptus to Smoothened in the Hedgehog signalosome complex.

Ranieri N, Thérond PP, Ruel L.

Nat Commun. 2014 Oct 7;5:5034. doi: 10.1038/ncomms6034.

PMID:
25289679
12.
13.

Evidence for a novel feedback loop in the Hedgehog pathway involving Smoothened and Fused.

Claret S, Sanial M, Plessis A.

Curr Biol. 2007 Aug 7;17(15):1326-33. Epub 2007 Jul 19.

14.

Distinct phosphorylations on kinesin costal-2 mediate differential hedgehog signaling strength.

Ranieri N, Ruel L, Gallet A, Raisin S, Thérond PP.

Dev Cell. 2012 Feb 14;22(2):279-94. doi: 10.1016/j.devcel.2011.12.002. Epub 2012 Feb 2.

15.

A large complex containing Patched and Smoothened initiates Hedgehog signaling in Drosophila.

Walthall SL, Moses M, Horabin JI.

J Cell Sci. 2007 Mar 1;120(Pt 5):826-37. Epub 2007 Feb 6.

16.

The Kinesin-related protein Costal2 associates with membranes in a Hedgehog-sensitive, Smoothened-independent manner.

Stegman MA, Goetz JA, Ascano M Jr, Ogden SK, Nybakken KE, Robbins DJ.

J Biol Chem. 2004 Feb 20;279(8):7064-71. Epub 2003 Nov 28.

17.

Stability and association of Smoothened, Costal2 and Fused with Cubitus interruptus are regulated by Hedgehog.

Ruel L, Rodriguez R, Gallet A, Lavenant-Staccini L, Thérond PP.

Nat Cell Biol. 2003 Oct;5(10):907-13. Epub 2003 Oct 1.

PMID:
14523402
18.

Hedgehog signalling: how to get from Smo to Ci and Gli.

Østerlund T, Kogerman P.

Trends Cell Biol. 2006 Apr;16(4):176-80. Epub 2006 Mar 3. Review.

PMID:
16516476
19.

Hedgehog activates fused through phosphorylation to elicit a full spectrum of pathway responses.

Zhou Q, Kalderon D.

Dev Cell. 2011 Jun 14;20(6):802-14. doi: 10.1016/j.devcel.2011.04.020.

20.

Altered localization of Drosophila Smoothened protein activates Hedgehog signal transduction.

Zhu AJ, Zheng L, Suyama K, Scott MP.

Genes Dev. 2003 May 15;17(10):1240-52. Epub 2003 May 2.

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