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Items: 1 to 20 of 115

1.

Life, death and E2F: linking proliferation control and DNA damage signaling via E2F1.

Rogoff HA, Kowalik TF.

Cell Cycle. 2004 Jul;3(7):845-6. Epub 2004 Jul 14. Review.

PMID:
15190206
2.

Apoptosis associated with deregulated E2F activity is dependent on E2F1 and Atm/Nbs1/Chk2.

Rogoff HA, Pickering MT, Frame FM, Debatis ME, Sanchez Y, Jones S, Kowalik TF.

Mol Cell Biol. 2004 Apr;24(7):2968-77.

3.

E2F1 uses the ATM signaling pathway to induce p53 and Chk2 phosphorylation and apoptosis.

Powers JT, Hong S, Mayhew CN, Rogers PM, Knudsen ES, Johnson DG.

Mol Cancer Res. 2004 Apr;2(4):203-14.

4.

DNA damage signals through differentially modified E2F1 molecules to induce apoptosis.

Carnevale J, Palander O, Seifried LA, Dick FA.

Mol Cell Biol. 2012 Mar;32(5):900-12. doi: 10.1128/MCB.06286-11. Epub 2011 Dec 19.

5.

The E2F family and the role of E2F1 in apoptosis.

Wu Z, Zheng S, Yu Q.

Int J Biochem Cell Biol. 2009 Dec;41(12):2389-97. doi: 10.1016/j.biocel.2009.06.004. Epub 2009 Jun 17.

PMID:
19539777
6.

Translating DNA damage into cancer cell death-A roadmap for E2F1 apoptotic signalling and opportunities for new drug combinations to overcome chemoresistance.

Engelmann D, Pützer BM.

Drug Resist Updat. 2010 Aug-Oct;13(4-5):119-31. doi: 10.1016/j.drup.2010.06.001. Epub 2010 Aug 1. Review.

PMID:
20675184
8.
9.

Rb inactivation leads to E2F1-mediated DNA double-strand break accumulation.

Pickering MT, Kowalik TF.

Oncogene. 2006 Feb 2;25(5):746-55.

PMID:
16186801
10.

Co-deleting Pten with Rb in retinal progenitor cells in mice results in fully penetrant bilateral retinoblastomas.

Xie C, Lu H, Nomura A, Hanse EA, Forster CL, Parker JB, Linden MA, Karasch C, Hallstrom TC.

Mol Cancer. 2015 Apr 24;14:93. doi: 10.1186/s12943-015-0360-y.

11.

E2F1 and E2F3 activate ATM through distinct mechanisms to promote E1A-induced apoptosis.

Hong S, Paulson QX, Johnson DG.

Cell Cycle. 2008 Feb 1;7(3):391-400. Epub 2007 Nov 6.

PMID:
18235226
12.
13.
14.

Hepatitis B virus X protein via the p38MAPK pathway induces E2F1 release and ATR kinase activation mediating p53 apoptosis.

Wang WH, Hullinger RL, Andrisani OM.

J Biol Chem. 2008 Sep 12;283(37):25455-67. doi: 10.1074/jbc.M801934200. Epub 2008 Jul 7.

15.

MiR-15 and miR-16 are direct transcriptional targets of E2F1 that limit E2F-induced proliferation by targeting cyclin E.

Ofir M, Hacohen D, Ginsberg D.

Mol Cancer Res. 2011 Apr;9(4):440-7. doi: 10.1158/1541-7786.MCR-10-0344. Epub 2011 Mar 31.

16.

E2F1 induces MRN foci formation and a cell cycle checkpoint response in human fibroblasts.

Frame FM, Rogoff HA, Pickering MT, Cress WD, Kowalik TF.

Oncogene. 2006 Jun 1;25(23):3258-66. Epub 2006 Jan 23.

PMID:
16434972
17.

E2f1, E2f2, and E2f3 control E2F target expression and cellular proliferation via a p53-dependent negative feedback loop.

Timmers C, Sharma N, Opavsky R, Maiti B, Wu L, Wu J, Orringer D, Trikha P, Saavedra HI, Leone G.

Mol Cell Biol. 2007 Jan;27(1):65-78. Erratum in: Mol Cell Biol. 2012 May;32(9):1758.

19.

RB·E2F1 complex mediates DNA damage responses through transcriptional regulation of ZBRK1.

Liao CC, Tsai CY, Chang WC, Lee WH, Wang JM.

J Biol Chem. 2010 Oct 22;285(43):33134-43. doi: 10.1074/jbc.M110.143461. Epub 2010 Aug 16.

20.

Caspase 2 is both required for p53-mediated apoptosis and downregulated by p53 in a p21-dependent manner.

Baptiste-Okoh N, Barsotti AM, Prives C.

Cell Cycle. 2008 May 1;7(9):1133-8. Epub 2008 Feb 19.

PMID:
18418048

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