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Items: 1 to 20 of 85

1.

11Beta-hydroxysteroid dehydrogenase inhibition improves cognitive function in healthy elderly men and type 2 diabetics.

Sandeep TC, Yau JL, MacLullich AM, Noble J, Deary IJ, Walker BR, Seckl JR.

Proc Natl Acad Sci U S A. 2004 Apr 27;101(17):6734-9. Epub 2004 Apr 7.

2.

Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 lowers intraocular pressure in patients with ocular hypertension.

Rauz S, Cheung CM, Wood PJ, Coca-Prados M, Walker EA, Murray PI, Stewart PM.

QJM. 2003 Jul;96(7):481-90.

3.

Effect of hyperlipidemia on 11β-hydroxysteroid-dehydrogenase, glucocorticoid receptor, and leptin expression in insulin-sensitive tissues of cats.

Sieber-Ruckstuhl NS, Zini E, Osto M, Franchini M, Boretti FS, Meli ML, Sigrist B, Lutz TA, Reusch CE.

Domest Anim Endocrinol. 2010 Nov;39(4):222-30. doi: 10.1016/j.domaniend.2010.06.003. Epub 2010 Jul 14.

PMID:
20688460
4.

Increased expression of 11beta-hydroxysteroid dehydrogenase type 1 in type 2 diabetic myotubes.

Abdallah BM, Beck-Nielsen H, Gaster M.

Eur J Clin Invest. 2005 Oct;35(10):627-34.

PMID:
16178882
5.

Growth hormone, insulin-like growth factor-I and the cortisol-cortisone shuttle.

Stewart PM, Toogood AA, Tomlinson JW.

Horm Res. 2001;56 Suppl 1:1-6. Review.

PMID:
11786677
6.
7.

Expression and functional consequences of 11beta-hydroxysteroid dehydrogenase activity in human bone.

Cooper MS, Walker EA, Bland R, Fraser WD, Hewison M, Stewart PM.

Bone. 2000 Sep;27(3):375-81.

PMID:
10962348
9.

Differential expression of placental 11β-hydroxysteroid dehydrogenases in pregnant women with diet-treated gestational diabetes mellitus.

Ma R, Liu J, Wu L, Sun J, Yang Z, Yu C, Yuan P, Xiao X.

Steroids. 2012 Jun;77(7):798-805. doi: 10.1016/j.steroids.2012.03.007. Epub 2012 Mar 25.

PMID:
22469619
10.

The role of 11beta-hydroxysteroid dehydrogenases in the brain.

Holmes MC, Seckl JR.

Mol Cell Endocrinol. 2006 Mar 27;248(1-2):9-14. Epub 2006 Jan 18. Review.

PMID:
16413106
12.

Effects of the 11 beta-hydroxysteroid dehydrogenase inhibitor carbenoxolone on insulin sensitivity in men with type 2 diabetes.

Andrews RC, Rooyackers O, Walker BR.

J Clin Endocrinol Metab. 2003 Jan;88(1):285-91.

PMID:
12519867
13.

Differential expression and activity of 11beta-hydroxysteroid dehydrogenase in human placenta and fetal membranes from pregnancies with intrauterine growth restriction.

Wächter R, Masarik L, Bürzle M, Mallik A, von Mandach U.

Fetal Diagn Ther. 2009;25(3):328-35. doi: 10.1159/000235879. Epub 2009 Sep 22.

PMID:
19776596
14.

Lack of regulation of 11beta-hydroxysteroid dehydrogenase type 1 during short-term manipulation of GH in patients with hypopituitarism.

Sigurjonsdottir HA, Andrew R, Stimson RH, Johannsson G, Walker BR.

Eur J Endocrinol. 2009 Sep;161(3):375-80. doi: 10.1530/EJE-09-0315. Epub 2009 Jun 23.

15.

Type 1 11beta-hydroxysteroid dehydrogenase as universal drug target in metabolic diseases?

Oppermann U.

Endocr Metab Immune Disord Drug Targets. 2006 Sep;6(3):259-69. Review.

PMID:
17017977
16.
17.

In the search for specific inhibitors of human 11beta-hydroxysteroid-dehydrogenases (11beta-HSDs): chenodeoxycholic acid selectively inhibits 11beta-HSD-I.

Diederich S, Grossmann C, Hanke B, Quinkler M, Herrmann M, Bähr V, Oelkers W.

Eur J Endocrinol. 2000 Feb;142(2):200-7.

18.

Partial deficiency or short-term inhibition of 11beta-hydroxysteroid dehydrogenase type 1 improves cognitive function in aging mice.

Sooy K, Webster SP, Noble J, Binnie M, Walker BR, Seckl JR, Yau JL.

J Neurosci. 2010 Oct 13;30(41):13867-72. doi: 10.1523/JNEUROSCI.2783-10.2010.

20.

Th2 cytokine-induced upregulation of 11beta-hydroxysteroid dehydrogenase-1 facilitates glucocorticoid suppression of proasthmatic airway smooth muscle function.

Hu A, Fatma S, Cao J, Grunstein JS, Nino G, Grumbach Y, Grunstein MM.

Am J Physiol Lung Cell Mol Physiol. 2009 May;296(5):L790-803. doi: 10.1152/ajplung.90572.2008. Epub 2009 Feb 27.

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