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Items: 1 to 20 of 94

1.

Hepatocytes: critical for glucose homeostasis.

Klover PJ, Mooney RA.

Int J Biochem Cell Biol. 2004 May;36(5):753-8. Review.

PMID:
15061128
3.

Biomedicine. New insights into type 2 diabetes.

Alper J.

Science. 2000 Jul 7;289(5476):37-9.

PMID:
10928926
4.

Suppressor of cytokine signaling 3 is a physiological regulator of adipocyte insulin signaling.

Shi H, Tzameli I, Bjørbaek C, Flier JS.

J Biol Chem. 2004 Aug 13;279(33):34733-40.

5.

Somatostatin receptor subtype-2-deficient mice with diet-induced obesity have hyperglycemia, nonfasting hyperglucagonemia, and decreased hepatic glycogen deposition.

Singh V, Grötzinger C, Nowak KW, Zacharias S, Göncz E, Pless G, Sauer IM, Eichhorn I, Pfeiffer-Guglielmi B, Hamprecht B, Wiedenmann B, Plöckinger U, Strowski MZ.

Endocrinology. 2007 Aug;148(8):3887-99.

PMID:
17525126
6.

Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes.

Senn JJ, Klover PJ, Nowak IA, Zimmers TA, Koniaris LG, Furlanetto RW, Mooney RA.

J Biol Chem. 2003 Apr 18;278(16):13740-6.

7.

Dual role of the coactivator TORC2 in modulating hepatic glucose output and insulin signaling.

Canettieri G, Koo SH, Berdeaux R, Heredia J, Hedrick S, Zhang X, Montminy M.

Cell Metab. 2005 Nov;2(5):331-8.

8.

Counterpoint: Interleukin-6 does not have a beneficial role in insulin sensitivity and glucose homeostasis.

Mooney RA.

J Appl Physiol (1985). 2007 Feb;102(2):816-8; discussion 818-9. No abstract available.

PMID:
17284655
9.

Modulation of insulin action.

Pirola L, Johnston AM, Van Obberghen E.

Diabetologia. 2004 Feb;47(2):170-84. Review.

PMID:
14722654
10.

The novel roles of liver for compensation of insulin resistance in human growth hormone transgenic rats.

Cho Y, Ariga M, Uchijima Y, Kimura K, Rho JY, Furuhata Y, Hakuno F, Yamanouchi K, Nishihara M, Takahashi S.

Endocrinology. 2006 Nov;147(11):5374-84.

PMID:
16916956
11.

Deletion of cd39/entpd1 results in hepatic insulin resistance.

Enjyoji K, Kotani K, Thukral C, Blumel B, Sun X, Wu Y, Imai M, Friedman D, Csizmadia E, Bleibel W, Kahn BB, Robson SC.

Diabetes. 2008 Sep;57(9):2311-20. doi: 10.2337/db07-1265.

12.

Point: Interleukin-6 does have a beneficial role in insulin sensitivity and glucose homeostasis.

Pedersen BK, Febbraio MA.

J Appl Physiol (1985). 2007 Feb;102(2):814-6. No abstract available.

13.

Hepatic TRAF2 regulates glucose metabolism through enhancing glucagon responses.

Chen Z, Sheng L, Shen H, Zhao Y, Wang S, Brink R, Rui L.

Diabetes. 2012 Mar;61(3):566-73. doi: 10.2337/db11-0474.

16.

Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes.

Ozcan U, Cao Q, Yilmaz E, Lee AH, Iwakoshi NN, Ozdelen E, Tuncman G, Görgün C, Glimcher LH, Hotamisligil GS.

Science. 2004 Oct 15;306(5695):457-61.

17.
18.

Modified Si-Miao-San extract inhibits inflammatory response and modulates insulin sensitivity in hepatocytes through an IKKβ/IRS-1/Akt-dependent pathway.

Liu K, Luo T, Zhang Z, Wang T, Kou J, Liu B, Huang F.

J Ethnopharmacol. 2011 Jul 14;136(3):473-9. doi: 10.1016/j.jep.2011.01.051.

PMID:
21296137
19.

Hepatitis C virus down-regulates insulin receptor substrates 1 and 2 through up-regulation of suppressor of cytokine signaling 3.

Kawaguchi T, Yoshida T, Harada M, Hisamoto T, Nagao Y, Ide T, Taniguchi E, Kumemura H, Hanada S, Maeyama M, Baba S, Koga H, Kumashiro R, Ueno T, Ogata H, Yoshimura A, Sata M.

Am J Pathol. 2004 Nov;165(5):1499-508.

20.
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