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Items: 1 to 20 of 158


eIF4AIII binds spliced mRNA in the exon junction complex and is essential for nonsense-mediated decay.

Shibuya T, Tange TØ, Sonenberg N, Moore MJ.

Nat Struct Mol Biol. 2004 Apr;11(4):346-51. Epub 2004 Mar 21.


An eIF4AIII-containing complex required for mRNA localization and nonsense-mediated mRNA decay.

Palacios IM, Gatfield D, St Johnston D, Izaurralde E.

Nature. 2004 Feb 19;427(6976):753-7.


The exon junction core complex is locked onto RNA by inhibition of eIF4AIII ATPase activity.

Ballut L, Marchadier B, Baguet A, Tomasetto C, Séraphin B, Le Hir H.

Nat Struct Mol Biol. 2005 Oct;12(10):861-9. Epub 2005 Sep 18.


Exon junction complex enhances translation of spliced mRNAs at multiple steps.

Lee HC, Choe J, Chi SG, Kim YK.

Biochem Biophys Res Commun. 2009 Jul 3;384(3):334-40. doi: 10.1016/j.bbrc.2009.04.123. Epub 2009 May 3.


The three-dimensional arcitecture of the EJC core.

Stroupe ME, Tange TØ, Thomas DR, Moore MJ, Grigorieff N.

J Mol Biol. 2006 Jul 21;360(4):743-9. Epub 2006 Jun 5.


Association of the breast cancer protein MLN51 with the exon junction complex via its speckle localizer and RNA binding module.

Degot S, Le Hir H, Alpy F, Kedinger V, Stoll I, Wendling C, Seraphin B, Rio MC, Tomasetto C.

J Biol Chem. 2004 Aug 6;279(32):33702-15. Epub 2004 May 27.


Human spliceosomal protein CWC22 plays a role in coupling splicing to exon junction complex deposition and nonsense-mediated decay.

Alexandrov A, Colognori D, Shu MD, Steitz JA.

Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):21313-8. doi: 10.1073/pnas.1219725110. Epub 2012 Dec 10.


A nuclear translation-like factor eIF4AIII is recruited to the mRNA during splicing and functions in nonsense-mediated decay.

Ferraiuolo MA, Lee CS, Ler LW, Hsu JL, Costa-Mattioli M, Luo MJ, Reed R, Sonenberg N.

Proc Natl Acad Sci U S A. 2004 Mar 23;101(12):4118-23. Epub 2004 Mar 15.


Mechanism of ATP turnover inhibition in the EJC.

Nielsen KH, Chamieh H, Andersen CB, Fredslund F, Hamborg K, Le Hir H, Andersen GR.

RNA. 2009 Jan;15(1):67-75. doi: 10.1261/rna.1283109. Epub 2008 Nov 25.


Structure of the exon junction core complex with a trapped DEAD-box ATPase bound to RNA.

Andersen CB, Ballut L, Johansen JS, Chamieh H, Nielsen KH, Oliveira CL, Pedersen JS, Séraphin B, Le Hir H, Andersen GR.

Science. 2006 Sep 29;313(5795):1968-72. Epub 2006 Aug 24.


Structural insights into the exon junction complex.

Le Hir H, Andersen GR.

Curr Opin Struct Biol. 2008 Feb;18(1):112-9. doi: 10.1016/ Review.


The crystal structure of the exon junction complex reveals how it maintains a stable grip on mRNA.

Bono F, Ebert J, Lorentzen E, Conti E.

Cell. 2006 Aug 25;126(4):713-25.


MLN51 stimulates the RNA-helicase activity of eIF4AIII.

Noble CG, Song H.

PLoS One. 2007 Mar 21;2(3):e303.


Phosphorylation of Y14 modulates its interaction with proteins involved in mRNA metabolism and influences its methylation.

Hsu IaW, Hsu M, Li C, Chuang TW, Lin RI, Tarn WY.

J Biol Chem. 2005 Oct 14;280(41):34507-12. Epub 2005 Aug 12.


eIF4A3 is a novel component of the exon junction complex.

Chan CC, Dostie J, Diem MD, Feng W, Mann M, Rappsilber J, Dreyfuss G.

RNA. 2004 Feb;10(2):200-9.


eIF4AIII enhances translation of nuclear cap-binding complex-bound mRNAs by promoting disruption of secondary structures in 5'UTR.

Choe J, Ryu I, Park OH, Park J, Cho H, Yoo JS, Chi SW, Kim MK, Song HK, Kim YK.

Proc Natl Acad Sci U S A. 2014 Oct 28;111(43):E4577-86. doi: 10.1073/pnas.1409695111. Epub 2014 Oct 13.


The RNA-binding protein Y14 inhibits mRNA decapping and modulates processing body formation.

Chuang TW, Chang WL, Lee KM, Tarn WY.

Mol Biol Cell. 2013 Jan;24(1):1-13. doi: 10.1091/mbc.E12-03-0217. Epub 2012 Oct 31.


Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements.

Gehring NH, Kunz JB, Neu-Yilik G, Breit S, Viegas MH, Hentze MW, Kulozik AE.

Mol Cell. 2005 Oct 7;20(1):65-75.

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