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Items: 1 to 20 of 91


From silencing to gene expression: real-time analysis in single cells.

Janicki SM, Tsukamoto T, Salghetti SE, Tansey WP, Sachidanandam R, Prasanth KV, Ried T, Shav-Tal Y, Bertrand E, Singer RH, Spector DL.

Cell. 2004 Mar 5;116(5):683-98.


Visualizing gene expression: an unfolding story.

Henikoff S.

Cell. 2004 Mar 5;116(5):633-4.


Mechanisms of HP1-mediated gene silencing in Drosophila.

Danzer JR, Wallrath LL.

Development. 2004 Aug;131(15):3571-80. Epub 2004 Jun 23.


In vivo HP1 targeting causes large-scale chromatin condensation and enhanced histone lysine methylation.

Verschure PJ, van der Kraan I, de Leeuw W, van der Vlag J, Carpenter AE, Belmont AS, van Driel R.

Mol Cell Biol. 2005 Jun;25(11):4552-64.


Regulated recruitment of HP1 to a euchromatic gene induces mitotically heritable, epigenetic gene silencing: a mammalian cell culture model of gene variegation.

Ayyanathan K, Lechner MS, Bell P, Maul GG, Schultz DC, Yamada Y, Tanaka K, Torigoe K, Rauscher FJ 3rd.

Genes Dev. 2003 Aug 1;17(15):1855-69. Epub 2003 Jul 17.


Central role of Drosophila SU(VAR)3-9 in histone H3-K9 methylation and heterochromatic gene silencing.

Schotta G, Ebert A, Krauss V, Fischer A, Hoffmann J, Rea S, Jenuwein T, Dorn R, Reuter G.

EMBO J. 2002 Mar 1;21(5):1121-31.


Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain.

Bannister AJ, Zegerman P, Partridge JF, Miska EA, Thomas JO, Allshire RC, Kouzarides T.

Nature. 2001 Mar 1;410(6824):120-4.


The changing faces of HP1: From heterochromatin formation and gene silencing to euchromatic gene expression: HP1 acts as a positive regulator of transcription.

Kwon SH, Workman JL.

Bioessays. 2011 Apr;33(4):280-9. doi: 10.1002/bies.201000138. Epub 2011 Jan 27. Review.


HP1 recruits activity-dependent neuroprotective protein to H3K9me3 marked pericentromeric heterochromatin for silencing of major satellite repeats.

Mosch K, Franz H, Soeroes S, Singh PB, Fischle W.

PLoS One. 2011 Jan 18;6(1):e15894. doi: 10.1371/journal.pone.0015894.


Daxx and histone deacetylase II associate with chromatin through an interaction with core histones and the chromatin-associated protein Dek.

Hollenbach AD, McPherson CJ, Mientjes EJ, Iyengar R, Grosveld G.

J Cell Sci. 2002 Aug 15;115(Pt 16):3319-30.


Tethering of HP1 proteins to chromatin is relieved by phosphoacetylation of histone H3.

Mateescu B, England P, Halgand F, Yaniv M, Muchardt C.

EMBO Rep. 2004 May;5(5):490-6. Epub 2004 Apr 23.


Methyl-CpG binding domain 1 (MBD1) interacts with the Suv39h1-HP1 heterochromatic complex for DNA methylation-based transcriptional repression.

Fujita N, Watanabe S, Ichimura T, Tsuruzoe S, Shinkai Y, Tachibana M, Chiba T, Nakao M.

J Biol Chem. 2003 Jun 27;278(26):24132-8. Epub 2003 Apr 23.


DYRK1A phoshorylates histone H3 to differentially regulate the binding of HP1 isoforms and antagonize HP1-mediated transcriptional repression.

Jang SM, Azebi S, Soubigou G, Muchardt C.

EMBO Rep. 2014 Jun;15(6):686-94. doi: 10.15252/embr.201338356. Epub 2014 May 12.


Human heterochromatin protein 1 isoforms HP1(Hsalpha) and HP1(Hsbeta) interfere with hTERT-telomere interactions and correlate with changes in cell growth and response to ionizing radiation.

Sharma GG, Hwang KK, Pandita RK, Gupta A, Dhar S, Parenteau J, Agarwal M, Worman HJ, Wellinger RJ, Pandita TK.

Mol Cell Biol. 2003 Nov;23(22):8363-76.


Coordinated methyl and RNA binding is required for heterochromatin localization of mammalian HP1alpha.

Muchardt C, Guilleme M, Seeler JS, Trouche D, Dejean A, Yaniv M.

EMBO Rep. 2002 Oct;3(10):975-81. Epub 2002 Sep 13.


Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi.

Volpe TA, Kidner C, Hall IM, Teng G, Grewal SI, Martienssen RA.

Science. 2002 Sep 13;297(5588):1833-7. Epub 2002 Aug 22.

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