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Items: 1 to 20 of 236

1.

Regulation of AMPA receptor gating by ligand binding core dimers.

Horning MS, Mayer ML.

Neuron. 2004 Feb 5;41(3):379-88.

2.

Structural basis for AMPA receptor activation and ligand selectivity: crystal structures of five agonist complexes with the GluR2 ligand-binding core.

Hogner A, Kastrup JS, Jin R, Liljefors T, Mayer ML, Egebjerg J, Larsen IK, Gouaux E.

J Mol Biol. 2002 Sep 6;322(1):93-109.

PMID:
12215417
3.

Stargazin interaction with alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors is critically dependent on the amino acid at the narrow constriction of the ion channel.

Körber C, Werner M, Hoffmann J, Sager C, Tietze M, Schmid SM, Kott S, Hollmann M.

J Biol Chem. 2007 Jun 29;282(26):18758-66. Epub 2007 May 4.

4.
5.

Mechanism of glutamate receptor desensitization.

Sun Y, Olson R, Horning M, Armstrong N, Mayer M, Gouaux E.

Nature. 2002 May 16;417(6886):245-53.

PMID:
12015593
6.

AMPA receptor binding cleft mutations that alter affinity, efficacy, and recovery from desensitization.

Robert A, Armstrong N, Gouaux JE, Howe JR.

J Neurosci. 2005 Apr 13;25(15):3752-62.

7.

A binding site tyrosine shapes desensitization kinetics and agonist potency at GluR2. A mutagenic, kinetic, and crystallographic study.

Holm MM, Naur P, Vestergaard B, Geballe MT, Gajhede M, Kastrup JS, Traynelis SF, Egebjerg J.

J Biol Chem. 2005 Oct 21;280(42):35469-76. Epub 2005 Aug 15.

8.

Block of kainate receptor desensitization uncovers a key trafficking checkpoint.

Priel A, Selak S, Lerma J, Stern-Bach Y.

Neuron. 2006 Dec 21;52(6):1037-46.

9.

Block of AMPA receptor desensitization by a point mutation outside the ligand-binding domain.

Yelshansky MV, Sobolevsky AI, Jatzke C, Wollmuth LP.

J Neurosci. 2004 May 19;24(20):4728-36.

11.

Structure-based functional design of chemical ligands for AMPA-subtype glutamate receptors.

Zeng L, Chen K, Muller M, Zhou MM.

J Mol Neurosci. 2004;24(1):81-4.

PMID:
15314254
12.

Identification of amino acid residues in GluR1 responsible for ligand binding and desensitization.

Banke TG, Greenwood JR, Christensen JK, Liljefors T, Traynelis SF, Schousboe A, Pickering DS.

J Neurosci. 2001 May 1;21(9):3052-62.

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15.

Structure-based rational design of chemical ligands for AMPA-subtype glutamate receptors.

Zeng L, Chen CH, Muller M, Zhou MM.

J Mol Neurosci. 2003;20(3):345-8.

PMID:
14501018
16.

AMPA receptor activation; not a square dance.

Stern-Bach Y.

Neuron. 2004 Feb 5;41(3):309-11.

17.

Pharmacological characterization, localization, and regulation of ionotropic glutamate receptors in skate horizontal cells.

Kreitzer MA, Birnbaum AD, Qian H, Malchow RP.

Vis Neurosci. 2009 Jul-Aug;26(4):375-87. doi: 10.1017/S0952523809990149. Epub 2009 Aug 14.

PMID:
19678977
18.

Disruption of agonist and ligand activity in an AMPA glutamate receptor splice-variable domain deletion mutant.

Johnson WD 2nd, Parandaman V, Onaivi ES, Taylor RE, Akinshola BE.

Brain Res. 2008 Jul 30;1222:18-30. doi: 10.1016/j.brainres.2008.05.035. Epub 2008 May 23.

PMID:
18585685
19.
20.

A domain linking the AMPA receptor agonist binding site to the ion pore controls gating and causes lurcher properties when mutated.

Schmid SM, Körber C, Herrmann S, Werner M, Hollmann M.

J Neurosci. 2007 Nov 7;27(45):12230-41.

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