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Items: 1 to 20 of 124

1.

Effect of ajoene, the major antiplatelet compound from garlic, on platelet thrombus formation.

Apitz-Castro R, Badimon JJ, Badimon L.

Thromb Res. 1992 Oct 15;68(2):145-55.

PMID:
1475777
2.
3.
4.

Ajoene, the antiplatelet compound derived from garlic, specifically inhibits platelet release reaction by affecting the plasma membrane internal microviscosity.

Rendu F, Daveloose D, Debouzy JC, Bourdeau N, Levy-Toledano S, Jain MK, Apitz-Castro R.

Biochem Pharmacol. 1989 Apr 15;38(8):1321-8.

PMID:
2539823
5.

The molecular basis of the antiplatelet action of ajoene: direct interaction with the fibrinogen receptor.

Apitz-Castro R, Ledezma E, Escalante J, Jain MK.

Biochem Biophys Res Commun. 1986 Nov 26;141(1):145-50. Erratum in: Biochem Biophys Res Commun 1987 May 14;144(3):1348.

PMID:
3800991
6.

Real-time analysis of shear-dependent thrombus formation and its blockade by inhibitors of von Willebrand factor binding to platelets.

Alevriadou BR, Moake JL, Turner NA, Ruggeri ZM, Folie BJ, Phillips MD, Schreiber AB, Hrinda ME, McIntire LV.

Blood. 1993 Mar 1;81(5):1263-76.

7.

Effects of a garlic-derived principle (ajoene) on aggregation and arachidonic acid metabolism in human blood platelets.

Srivastava KC, Tyagi OD.

Prostaglandins Leukot Essent Fatty Acids. 1993 Aug;49(2):587-95.

PMID:
8415808
8.

Platelet-vessel wall interactions in thrombosis and restenosis role of von Willebrand factor.

Hoylaerts MF.

Verh K Acad Geneeskd Belg. 1997;59(3):161-83. Review.

PMID:
9490916
9.

Reversible prevention of platelet activation by (E,Z)-4,5,9-trithiadodeca-1,6,11-triene 9-oxide (ajoene) in dogs under extracorporeal circulation.

Apitz-Castro R, Ledezma E, Escalante J, Jorquera A, Pinãte FM, Moreno-Rea J, Carrillo G, Leal O, Jain MK.

Arzneimittelforschung. 1988 Jul;38(7):901-4.

PMID:
3207435
10.

Ajoene inhibits the activation of human endothelial cells induced by porcine cells: implications for xenotransplantation.

Benatuil L, Apitz-Castro R, Romano E.

Xenotransplantation. 2003 Jul;10(4):368-73.

PMID:
12795686
11.

Inhibition of phosphatidylcholine biosynthesis and cell proliferation in Trypanosoma cruzi by ajoene, an antiplatelet compound isolated from garlic.

Urbina JA, Marchan E, Lazardi K, Visbal G, Apitz-Castro R, Gil F, Aguirre T, Piras MM, Piras R.

Biochem Pharmacol. 1993 Jun 22;45(12):2381-7.

PMID:
8328978
13.

Antagonism of the GPIIb/IIIa receptor with the nonpeptidic molecule BIBU52: inhibition of platelet aggregation in vitro and antithrombotic efficacy in vivo.

Guth BD, Seewaldt-Becker E, Himmelsbach F, Weisenberger H, Müller TH.

J Cardiovasc Pharmacol. 1997 Aug;30(2):261-72.

PMID:
9269956
14.

Platelet thrombus formation on collagen type I. A model of deep vessel injury. Influence of blood rheology, von Willebrand factor, and blood coagulation.

Badimon L, Badimon JJ, Turitto VT, Vallabhajosula S, Fuster V.

Circulation. 1988 Dec;78(6):1431-42.

PMID:
3263902
15.

Inhibition by ajoene of protein tyrosine phosphatase activity in human platelets.

Villar R, Alvariño MT, Flores R.

Biochim Biophys Acta. 1997 Feb 8;1337(2):233-40.

PMID:
9048900
16.

Antitumor activity of Z-ajoene, a natural compound purified from garlic: antimitotic and microtubule-interaction properties.

Li M, Ciu JR, Ye Y, Min JM, Zhang LH, Wang K, Gares M, Cros J, Wright M, Leung-Tack J.

Carcinogenesis. 2002 Apr;23(4):573-9.

18.

Aurin tricarboxylic acid: a novel inhibitor of the association of von Willebrand factor and platelets.

Phillips MD, Moake JL, Nolasco L, Turner N.

Blood. 1988 Dec;72(6):1898-903.

19.

Platelet deposition induced by severely damaged vessel wall is inhibited by a boroarginine synthetic peptide with antithrombin activity.

Badimon JJ, Weng D, Chesebro JH, Fuster V, Badimon L.

Thromb Haemost. 1994 Apr;71(4):511-6.

PMID:
8052972
20.

Ajoene (natural garlic compound): a new anti-leukaemia agent for AML therapy.

Hassan HT.

Leuk Res. 2004 Jul;28(7):667-71. Review.

PMID:
15158086
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