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Items: 1 to 20 of 63

1.

Mouse models of pancreatic cancer: the fur is finally flying!

Leach SD.

Cancer Cell. 2004 Jan;5(1):7-11. Review.

2.

Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma.

Aguirre AJ, Bardeesy N, Sinha M, Lopez L, Tuveson DA, Horner J, Redston MS, DePinho RA.

Genes Dev. 2003 Dec 15;17(24):3112-26. Epub 2003 Dec 17.

3.

Deciphering the mechanisms of tumorigenesis in human pancreatic ductal epithelial cells.

Chang Z, Li Z, Wang X, Kang Y, Yuan Y, Niu J, Wang H, Chatterjee D, Fleming JB, Li M, Abbruzzese JL, Chiao PJ.

Clin Cancer Res. 2013 Feb 1;19(3):549-59. doi: 10.1158/1078-0432.CCR-12-0032. Epub 2013 Jan 22.

4.

K-Ras-driven pancreatic cancer mouse model for anticancer inhibitor analyses.

Cook N, Olive KP, Frese K, Tuveson DA.

Methods Enzymol. 2008;439:73-85. doi: 10.1016/S0076-6879(07)00406-5.

PMID:
18374157
5.

Delayed progression of pancreatic intraepithelial neoplasia in a conditional Kras(G12D) mouse model by a selective cyclooxygenase-2 inhibitor.

Funahashi H, Satake M, Dawson D, Huynh NA, Reber HA, Hines OJ, Eibl G.

Cancer Res. 2007 Aug 1;67(15):7068-71. Epub 2007 Jul 24.

6.

Where and when does pancreatic carcinoma start?

Lüttges J, Hahn S, Klöppel G.

Med Klin (Munich). 2004 Apr 15;99(4):191-5.

PMID:
15085289
7.

Origin of pancreatic ductal adenocarcinoma from atypical flat lesions: a comparative study in transgenic mice and human tissues.

Aichler M, Seiler C, Tost M, Siveke J, Mazur PK, Da Silva-Buttkus P, Bartsch DK, Langer P, Chiblak S, Dürr A, Höfler H, Klöppel G, Müller-Decker K, Brielmeier M, Esposito I.

J Pathol. 2012 Apr;226(5):723-34. doi: 10.1002/path.3017. Epub 2012 Jan 17.

PMID:
21984419
8.

Pancreatic ductal adenocarcinoma and acinar cells: a matter of differentiation and development?

Rooman I, Real FX.

Gut. 2012 Mar;61(3):449-58. doi: 10.1136/gut.2010.235804. Epub 2011 Jul 5. Review.

PMID:
21730103
9.

Identification and sequencing of the Syrian Golden hamster (Mesocricetus auratus) p16(INK4a) and p15(INK4b) cDNAs and their homozygous gene deletion in cheek pouch and pancreatic tumor cells.

Muscarella P, Knobloch TJ, Ulrich AB, Casto BC, Moniaux N, Wittel UA, Melvin WS, Pour PM, Song H, Gold B, Batra SK, Weghorst CM.

Gene. 2001 Oct 31;278(1-2):235-43.

PMID:
11707341
10.

Pancreatic carcinogenesis.

Koorstra JB, Hustinx SR, Offerhaus GJ, Maitra A.

Pancreatology. 2008;8(2):110-25. doi: 10.1159/000123838. Epub 2008 Apr 1. Review.

11.

Kras(G12D) and Smad4/Dpc4 haploinsufficiency cooperate to induce mucinous cystic neoplasms and invasive adenocarcinoma of the pancreas.

Izeradjene K, Combs C, Best M, Gopinathan A, Wagner A, Grady WM, Deng CX, Hruban RH, Adsay NV, Tuveson DA, Hingorani SR.

Cancer Cell. 2007 Mar;11(3):229-43.

12.

A gene expression signature of epithelial tubulogenesis and a role for ASPM in pancreatic tumor progression.

Wang WY, Hsu CC, Wang TY, Li CR, Hou YC, Chu JM, Lee CT, Liu MS, Su JJ, Jian KY, Huang SS, Jiang SS, Shan YS, Lin PW, Shen YY, Lee MT, Chan TS, Chang CC, Chen CH, Chang IS, Lee YL, Chen LT, Tsai KK.

Gastroenterology. 2013 Nov;145(5):1110-20. doi: 10.1053/j.gastro.2013.07.040. Epub 2013 Jul 27.

PMID:
23896173
14.

N-cadherin haploinsufficiency increases survival in a mouse model of pancreatic cancer.

Su Y, Li J, Witkiewicz AK, Brennan D, Neill T, Talarico J, Radice GL.

Oncogene. 2012 Oct 11;31(41):4484-9. doi: 10.1038/onc.2011.574. Epub 2011 Dec 12.

15.

Ductal origin of pancreatic adenocarcinomas induced by conditional activation of a human Ha-ras oncogene in rat pancreas.

Ueda S, Fukamachi K, Matsuoka Y, Takasuka N, Takeshita F, Naito A, Iigo M, Alexander DB, Moore MA, Saito I, Ochiya T, Tsuda H.

Carcinogenesis. 2006 Dec;27(12):2497-510. Epub 2006 Jun 13.

PMID:
16774944
16.

Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer.

Bardeesy N, Cheng KH, Berger JH, Chu GC, Pahler J, Olson P, Hezel AF, Horner J, Lauwers GY, Hanahan D, DePinho RA.

Genes Dev. 2006 Nov 15;20(22):3130-46.

17.

Ductal neoplasia of the pancreas: nosologic, clinicopathologic, and biologic aspects.

Adsay NV, Basturk O, Cheng JD, Andea AA.

Semin Radiat Oncol. 2005 Oct;15(4):254-64. Review.

PMID:
16183479
18.

Aberrant p16(INK4A) and DPC4/Smad4 expression in intraductal papillary mucinous tumours of the pancreas is associated with invasive ductal adenocarcinoma.

Biankin AV, Biankin SA, Kench JG, Morey AL, Lee CS, Head DR, Eckstein RP, Hugh TB, Henshall SM, Sutherland RL.

Gut. 2002 Jun;50(6):861-8.

19.

[Mechanistic insights for pancreatic carcinogenesis].

Furukawa T, Horii A.

Nihon Rinsho. 2006 Jan;64 Suppl 1:27-31. Review. Japanese. No abstract available.

PMID:
16457215
20.

The angiotensin-I-converting enzyme inhibitor enalapril and aspirin delay progression of pancreatic intraepithelial neoplasia and cancer formation in a genetically engineered mouse model of pancreatic cancer.

Fendrich V, Chen NM, Neef M, Waldmann J, Buchholz M, Feldmann G, Slater EP, Maitra A, Bartsch DK.

Gut. 2010 May;59(5):630-7. doi: 10.1136/gut.2009.188961. Epub 2009 Nov 1.

PMID:
19880966

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