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Items: 1 to 20 of 99

1.

Dual role of MEK/ERK signaling in senescence and transformation of intestinal epithelial cells.

Boucher MJ, Jean D, Vézina A, Rivard N.

Am J Physiol Gastrointest Liver Physiol. 2004 May;286(5):G736-46. Epub 2003 Dec 30.

2.

Constitutive activation of the MEK/ERK pathway inhibits intestinal epithelial cell differentiation.

Lemieux E, Boucher MJ, Mongrain S, Boudreau F, Asselin C, Rivard N.

Am J Physiol Gastrointest Liver Physiol. 2011 Oct;301(4):G719-30. doi: 10.1152/ajpgi.00508.2010. Epub 2011 Jul 7.

3.

Depletion of ERK2 but not ERK1 abrogates oncogenic Ras-induced senescence.

Shin J, Yang J, Lee JC, Baek KH.

Cell Signal. 2013 Dec;25(12):2540-7. doi: 10.1016/j.cellsig.2013.08.014. Epub 2013 Aug 30.

PMID:
23993963
4.

Involvement of the ERK signaling cascade in protein kinase C-mediated cell cycle arrest in intestinal epithelial cells.

Clark JA, Black AR, Leontieva OV, Frey MR, Pysz MA, Kunneva L, Woloszynska-Read A, Roy D, Black JD.

J Biol Chem. 2004 Mar 5;279(10):9233-47. Epub 2003 Dec 11.

5.

Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling.

Lin AW, Barradas M, Stone JC, van Aelst L, Serrano M, Lowe SW.

Genes Dev. 1998 Oct 1;12(19):3008-19.

6.

Senescence of human fibroblasts induced by oncogenic Raf.

Zhu J, Woods D, McMahon M, Bishop JM.

Genes Dev. 1998 Oct 1;12(19):2997-3007.

7.
10.

Human intestinal epithelial crypt cell survival and death: Complex modulations of Bcl-2 homologs by Fak, PI3-K/Akt-1, MEK/Erk, and p38 signaling pathways.

Harnois C, Demers MJ, Bouchard V, Vallée K, Gagné D, Fujita N, Tsuruo T, Vézina A, Beaulieu JF, Côté A, Vachon PH.

J Cell Physiol. 2004 Feb;198(2):209-22.

PMID:
14603523
11.
12.

Rapid mitogen-activated protein kinase activation by transforming growth factor alpha in wounded rat intestinal epithelial cells.

Göke M, Kanai M, Lynch-Devaney K, Podolsky DK.

Gastroenterology. 1998 Apr;114(4):697-705.

PMID:
9516390
13.

cAMP inhibits the proliferation of retinal pigmented epithelial cells through the inhibition of ERK1/2 in a PKA-independent manner.

Hecquet C, Lefevre G, Valtink M, Engelmann K, Mascarelli F.

Oncogene. 2002 Sep 5;21(39):6101-12.

14.

Activation and role of MAP kinase-dependent pathways in retinal pigment epithelial cells: ERK and RPE cell proliferation.

Hecquet C, Lefevre G, Valtink M, Engelmann K, Mascarelli F.

Invest Ophthalmol Vis Sci. 2002 Sep;43(9):3091-8.

PMID:
12202534
15.

Cell cycle- and protein kinase C-specific effects of resiniferatoxin and resiniferonol 9,13,14-ortho-phenylacetate in intestinal epithelial cells.

Frey MR, Clark JA, Bateman NW, Kazanietz MG, Black AR, Black JD.

Biochem Pharmacol. 2004 May 15;67(10):1873-86.

PMID:
15130764
16.

RASSF1A mediates p21Cip1/Waf1-dependent cell cycle arrest and senescence through modulation of the Raf-MEK-ERK pathway and inhibition of Akt.

Thaler S, Hähnel PS, Schad A, Dammann R, Schuler M.

Cancer Res. 2009 Mar 1;69(5):1748-57. doi: 10.1158/0008-5472.CAN-08-1377. Epub 2009 Feb 17.

18.
19.

Loss of active MEK1-ERK1/2 restores epithelial phenotype and morphogenesis in transdifferentiated MDCK cells.

Schramek H, Feifel E, Marschitz I, Golochtchapova N, Gstraunthaler G, Montesano R.

Am J Physiol Cell Physiol. 2003 Sep;285(3):C652-61. Erratum in: Am J Physiol Cell Physiol. 2003 Dec;285(6):C1561.

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