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Items: 1 to 20 of 136

1.

Homologous recombination deficiency leads to profound genetic instability in cells derived from Xrcc2-knockout mice.

Deans B, Griffin CS, O'Regan P, Jasin M, Thacker J.

Cancer Res. 2003 Dec 1;63(23):8181-7.

2.

Extensive chromosomal instability in Rad51d-deficient mouse cells.

Smiraldo PG, Gruver AM, Osborn JC, Pittman DL.

Cancer Res. 2005 Mar 15;65(6):2089-96.

3.

Mammalian XRCC2 promotes the repair of DNA double-strand breaks by homologous recombination.

Johnson RD, Liu N, Jasin M.

Nature. 1999 Sep 23;401(6751):397-9.

PMID:
10517641
4.

XRCC2 is a nuclear RAD51-like protein required for damage-dependent RAD51 focus formation without the need for ATP binding.

O'Regan P, Wilson C, Townsend S, Thacker J.

J Biol Chem. 2001 Jun 22;276(25):22148-53. Epub 2001 Apr 11.

5.
6.

The RAD51 gene family, genetic instability and cancer.

Thacker J.

Cancer Lett. 2005 Mar 10;219(2):125-35. Review.

PMID:
15723711
7.

Homologous recombination proteins are associated with centrosomes and are required for mitotic stability.

Cappelli E, Townsend S, Griffin C, Thacker J.

Exp Cell Res. 2011 May 1;317(8):1203-13. doi: 10.1016/j.yexcr.2011.01.021. Epub 2011 Jan 27.

PMID:
21276791
9.

The involvement of key DNA repair pathways in the formation of chromosome rearrangements in embryonic stem cells.

Griffin C, Waard Hd, Deans B, Thacker J.

DNA Repair (Amst). 2005 Aug 15;4(9):1019-27.

PMID:
15979950
10.

Hypersensitivity to camptothecin in MSH2 deficient cells is correlated with a role for MSH2 protein in recombinational repair.

Pichierri P, Franchitto A, Piergentili R, Colussi C, Palitti F.

Carcinogenesis. 2001 Nov;22(11):1781-7.

PMID:
11698339
11.

The XRCC2 DNA repair gene from human and mouse encodes a novel member of the recA/RAD51 family.

Cartwright R, Tambini CE, Simpson PJ, Thacker J.

Nucleic Acids Res. 1998 Jul 1;26(13):3084-9.

12.

A naturally occurring genetic variant of human XRCC2 (R188H) confers increased resistance to cisplatin-induced DNA damage.

Danoy P, Sonoda E, Lathrop M, Takeda S, Matsuda F.

Biochem Biophys Res Commun. 2007 Jan 19;352(3):763-8. Epub 2006 Nov 27.

PMID:
17141189
14.

Double-strand-break-induced homologous recombination in mammalian cells.

Johnson RD, Jasin M.

Biochem Soc Trans. 2001 May;29(Pt 2):196-201. Review.

PMID:
11356153
15.

Therapeutic exploitation of tumor cell defects in homologous recombination.

Powell SN, Kachnic LA.

Anticancer Agents Med Chem. 2008 May;8(4):448-60. Review.

PMID:
18473729
16.

Defective DNA strand break repair after DNA damage in prostate cancer cells: implications for genetic instability and prostate cancer progression.

Fan R, Kumaravel TS, Jalali F, Marrano P, Squire JA, Bristow RG.

Cancer Res. 2004 Dec 1;64(23):8526-33.

17.

Overexpression of Rad51 inhibits double-strand break-induced homologous recombination but does not affect gene conversion tract lengths.

Paffett KS, Clikeman JA, Palmer S, Nickoloff JA.

DNA Repair (Amst). 2005 Jun 8;4(6):687-98.

PMID:
15878310
18.
19.

Rad51 overexpression promotes alternative double-strand break repair pathways and genome instability.

Richardson C, Stark JM, Ommundsen M, Jasin M.

Oncogene. 2004 Jan 15;23(2):546-53.

PMID:
14724582
20.

The XRCC genes: expanding roles in DNA double-strand break repair.

Thacker J, Zdzienicka MZ.

DNA Repair (Amst). 2004 Aug-Sep;3(8-9):1081-90. Review. Erratum in: DNA Repair (Amst). 2005 Feb 3;4(2):303-4.

PMID:
15279796

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