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Resemblance of osteophytes in experimental osteoarthritis to transforming growth factor beta-induced osteophytes: limited role of bone morphogenetic protein in early osteoarthritic osteophyte formation.

Blaney Davidson EN, Vitters EL, van Beuningen HM, van de Loo FA, van den Berg WB, van der Kraan PM.

Arthritis Rheum. 2007 Dec;56(12):4065-73.


Crucial role of synovial lining macrophages in the promotion of transforming growth factor beta-mediated osteophyte formation.

van Lent PL, Blom AB, van der Kraan P, Holthuysen AE, Vitters E, van Rooijen N, Smeets RL, Nabbe KC, van den Berg WB.

Arthritis Rheum. 2004 Jan;50(1):103-11.


TGF beta-induced cartilage repair is maintained but fibrosis is blocked in the presence of Smad7.

Blaney Davidson EN, Vitters EL, van den Berg WB, van der Kraan PM.

Arthritis Res Ther. 2006;8(3):R65.


Fibroblast-mediated delivery of growth factor complementary DNA into mouse joints induces chondrogenesis but avoids the disadvantages of direct viral gene transfer.

Gelse K, Jiang QJ, Aigner T, Ritter T, Wagner K, Pöschl E, von der Mark K, Schneider H.

Arthritis Rheum. 2001 Aug;44(8):1943-53.


Transforming growth factor-beta 1 stimulates articular chondrocyte proteoglycan synthesis and induces osteophyte formation in the murine knee joint.

van Beuningen HM, van der Kraan PM, Arntz OJ, van den Berg WB.

Lab Invest. 1994 Aug;71(2):279-90.


Connective tissue growth factor/CCN2 overexpression in mouse synovial lining results in transient fibrosis and cartilage damage.

Blaney Davidson EN, Vitters EL, Mooren FM, Oliver N, Berg WB, van der Kraan PM.

Arthritis Rheum. 2006 May;54(5):1653-61.


Involvement of the Wnt signaling pathway in experimental and human osteoarthritis: prominent role of Wnt-induced signaling protein 1.

Blom AB, Brockbank SM, van Lent PL, van Beuningen HM, Geurts J, Takahashi N, van der Kraan PM, van de Loo FA, Schreurs BW, Clements K, Newham P, van den Berg WB.

Arthritis Rheum. 2009 Feb;60(2):501-12. doi: 10.1002/art.24247.


Reduced chondrogenic potential of adipose tissue derived stromal cells correlates with an altered TGFbeta receptor and BMP profile and is overcome by BMP-6.

Hennig T, Lorenz H, Thiel A, Goetzke K, Dickhut A, Geiger F, Richter W.

J Cell Physiol. 2007 Jun;211(3):682-91.


Bone morphogenetic proteins promote cartilage differentiation and protect engineered artificial cartilage from fibroblast invasion and destruction.

Kaps C, Bramlage C, Smolian H, Haisch A, Ungethüm U, Burmester GR, Sittinger M, Gross G, Häupl T.

Arthritis Rheum. 2002 Jan;46(1):149-62.


Bone morphogenetic protein 2 stimulates articular cartilage proteoglycan synthesis in vivo but does not counteract interleukin-1alpha effects on proteoglycan synthesis and content.

Glansbeek HL, van Beuningen HM, Vitters EL, Morris EA, van der Kraan PM, van den Berg WB.

Arthritis Rheum. 1997 Jun;40(6):1020-8.


Crucial role of macrophages in matrix metalloproteinase-mediated cartilage destruction during experimental osteoarthritis: involvement of matrix metalloproteinase 3.

Blom AB, van Lent PL, Libregts S, Holthuysen AE, van der Kraan PM, van Rooijen N, van den Berg WB.

Arthritis Rheum. 2007 Jan;56(1):147-57.


Expression of bone morphogenetic protein 6 in healthy and osteoarthritic human articular chondrocytes and stimulation of matrix synthesis in vitro.

Bobacz K, Gruber R, Soleiman A, Erlacher L, Smolen JS, Graninger WB.

Arthritis Rheum. 2003 Sep;48(9):2501-8.

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