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Items: 1 to 20 of 174


Coupling of RAFTK/Pyk2 kinase with c-Abl and their role in the migration of breast cancer cells.

Zrihan-Licht S, Avraham S, Jiang S, Fu Y, Avraham HK.

Int J Oncol. 2004 Jan;24(1):153-9.


RAFTK/Pyk2 tyrosine kinase mediates the association of p190 RhoGAP with RasGAP and is involved in breast cancer cell invasion.

Zrihan-Licht S, Fu Y, Settleman J, Schinkmann K, Shaw L, Keydar I, Avraham S, Avraham H.

Oncogene. 2000 Mar 2;19(10):1318-28.


Csk homologous kinase associates with RAFTK/Pyk2 in breast cancer cells and negatively regulates its activation and breast cancer cell migration.

McShan GD, Zagozdzon R, Park SY, Zrihan-Licht S, Fu Y, Avraham S, Avraham H.

Int J Oncol. 2002 Jul;21(1):197-205.


Rho-dependent and -independent tyrosine phosphorylation of focal adhesion kinase, paxillin and p130Cas mediated by Ret kinase.

Murakami H, Iwashita T, Asai N, Iwata Y, Narumiya S, Takahashi M.

Oncogene. 1999 Mar 18;18(11):1975-82.


The related adhesion focal tyrosine kinase forms a complex with paxillin in hematopoietic cells.

Salgia R, Avraham S, Pisick E, Li JL, Raja S, Greenfield EA, Sattler M, Avraham H, Griffin JD.

J Biol Chem. 1996 Dec 6;271(49):31222-6.


The related adhesion focal tyrosine kinase is tyrosine-phosphorylated after beta1-integrin stimulation in B cells and binds to p130cas.

Astier A, Avraham H, Manie SN, Groopman J, Canty T, Avraham S, Freedman AS.

J Biol Chem. 1997 Jan 3;272(1):228-32.


The related adhesion focal tyrosine kinase differentially phosphorylates p130Cas and the Cas-like protein, p105HEF1.

Astier A, ManiƩ SN, Avraham H, Hirai H, Law SF, Zhang Y, Golemis EA, Fu Y, Druker BJ, Haghayeghi N, Freedman AS, Avraham S.

J Biol Chem. 1997 Aug 8;272(32):19719-24.


Activation of the focal adhesion kinase signaling pathway by structural alterations in the carboxyl-terminal region of c-Crk II.

Zvara A, Fajardo JE, Escalante M, Cotton G, Muir T, Kirsch KH, Birge RB.

Oncogene. 2001 Feb 22;20(8):951-61.


Cardiomyocyte apoptosis triggered by RAFTK/pyk2 via Src kinase is antagonized by paxillin.

Melendez J, Turner C, Avraham H, Steinberg SF, Schaefer E, Sussman MA.

J Biol Chem. 2004 Dec 17;279(51):53516-23. Epub 2004 Aug 22.


Serine phosphorylation of paxillin by heregulin-beta1: role of p38 mitogen activated protein kinase.

Vadlamudi R, Adam L, Talukder A, Mendelsohn J, Kumar R.

Oncogene. 1999 Dec 2;18(51):7253-64.


Phosphorylation of c-Crk II on the negative regulatory Tyr222 mediates nerve growth factor-induced cell spreading and morphogenesis.

Escalante M, Courtney J, Chin WG, Teng KK, Kim JI, Fajardo JE, Mayer BJ, Hempstead BL, Birge RB.

J Biol Chem. 2000 Aug 11;275(32):24787-97.


RAFTK/Pyk2 activation is mediated by trans-acting autophosphorylation in a Src-independent manner.

Park SY, Avraham HK, Avraham S.

J Biol Chem. 2004 Aug 6;279(32):33315-22. Epub 2004 May 27.


Differential regulation of components of the focal adhesion complex by heregulin: role of phosphatase SHP-2.

Vadlamudi RK, Adam L, Nguyen D, Santos M, Kumar R.

J Cell Physiol. 2002 Feb;190(2):189-99.


Signaling transduction pathway of angiotensin II in human mesangial cells: mediation of focal adhesion and GTPase activating proteins.

Shikata Y, Shikata K, Matsuda M, Sugimoto H, Wada J, Makino H.

Biochem Biophys Res Commun. 1999 Apr 2;257(1):234-8.


Activation of pyk2/related focal adhesion tyrosine kinase and focal adhesion kinase in cardiac remodeling.

Melendez J, Welch S, Schaefer E, Moravec CS, Avraham S, Avraham H, Sussman MA.

J Biol Chem. 2002 Nov 22;277(47):45203-10. Epub 2002 Sep 12.

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