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Engagement of CD153 (CD30 ligand) by CD30+ T cells inhibits class switch DNA recombination and antibody production in human IgD+ IgM+ B cells.

Cerutti A, Schaffer A, Goodwin RG, Shah S, Zan H, Ely S, Casali P.

J Immunol. 2000 Jul 15;165(2):786-94.


DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL.

Litinskiy MB, Nardelli B, Hilbert DM, He B, Schaffer A, Casali P, Cerutti A.

Nat Immunol. 2002 Sep;3(9):822-9. Epub 2002 Aug 5.


HIV-1 envelope triggers polyclonal Ig class switch recombination through a CD40-independent mechanism involving BAFF and C-type lectin receptors.

He B, Qiao X, Klasse PJ, Chiu A, Chadburn A, Knowles DM, Moore JP, Cerutti A.

J Immunol. 2006 Apr 1;176(7):3931-41.


Viral double-stranded RNA triggers Ig class switching by activating upper respiratory mucosa B cells through an innate TLR3 pathway involving BAFF.

Xu W, Santini PA, Matthews AJ, Chiu A, Plebani A, He B, Chen K, Cerutti A.

J Immunol. 2008 Jul 1;181(1):276-87.


Two new isotype-specific switching activities detected for Ig class switching.

Ma L, Wortis HH, Kenter AL.

J Immunol. 2002 Mar 15;168(6):2835-46.


Lymphoma B cells evade apoptosis through the TNF family members BAFF/BLyS and APRIL.

He B, Chadburn A, Jou E, Schattner EJ, Knowles DM, Cerutti A.

J Immunol. 2004 Mar 1;172(5):3268-79. Erratum in: J Immunol. 2004 Apr 15;172(8):following 5127.


B cell Rab7 mediates induction of activation-induced cytidine deaminase expression and class-switching in T-dependent and T-independent antibody responses.

Pone EJ, Lam T, Lou Z, Wang R, Chen Y, Liu D, Edinger AL, Xu Z, Casali P.

J Immunol. 2015 Apr 1;194(7):3065-78. doi: 10.4049/jimmunol.1401896. Epub 2015 Mar 4.


Downstream class switching leads to IgE antibody production by B lymphocytes lacking IgM switch regions.

Zhang T, Franklin A, Boboila C, McQuay A, Gallagher MP, Manis JP, Khamlichi AA, Alt FW.

Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3040-5. doi: 10.1073/pnas.0915072107. Epub 2010 Feb 1. Erratum in: Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5731.


B lymphocyte stimulator activates p38 mitogen-activated protein kinase in human Ig class switch recombination.

Yamada T, Zhang K, Yamada A, Zhu D, Saxon A.

Am J Respir Cell Mol Biol. 2005 May;32(5):388-94. Epub 2005 Jan 24.


B cells genetically deficient in the c-Rel transactivation domain have selective defects in germline CH transcription and Ig class switching.

Zelazowski P, Carrasco D, Rosas FR, Moorman MA, Bravo R, Snapper CM.

J Immunol. 1997 Oct 1;159(7):3133-9.


STAT6 is required for IL-4-induced germline Ig gene transcription and switch recombination.

Linehan LA, Warren WD, Thompson PA, Grusby MJ, Berton MT.

J Immunol. 1998 Jul 1;161(1):302-10.


B cells from p50/NF-kappa B knockout mice have selective defects in proliferation, differentiation, germ-line CH transcription, and Ig class switching.

Snapper CM, Zelazowski P, Rosas FR, Kehry MR, Tian M, Baltimore D, Sha WC.

J Immunol. 1996 Jan 1;156(1):183-91.


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