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Items: 1 to 20 of 267


DC-SIGN promotes exogenous MHC-I-restricted HIV-1 antigen presentation.

Moris A, Nobile C, Buseyne F, Porrot F, Abastado JP, Schwartz O.

Blood. 2004 Apr 1;103(7):2648-54. Epub 2003 Oct 23.


Targeting glycan modified OVA to murine DC-SIGN transgenic dendritic cells enhances MHC class I and II presentation.

Singh SK, Stephani J, Schaefer M, Kalay H, García-Vallejo JJ, den Haan J, Saeland E, Sparwasser T, van Kooyk Y.

Mol Immunol. 2009 Dec;47(2-3):164-74. doi: 10.1016/j.molimm.2009.09.026. Epub 2009 Oct 8.


Role of DC-SIGN in the activation of dendritic cells by HPV-16 L1 virus-like particle vaccine.

García-Piñeres AJ, Hildesheim A, Trivett M, Williams M, Wu L, Kewalramani VN, Pinto LA.

Eur J Immunol. 2006 Feb;36(2):437-45.


The dendritic cell-specific adhesion receptor DC-SIGN internalizes antigen for presentation to T cells.

Engering A, Geijtenbeek TB, van Vliet SJ, Wijers M, van Liempt E, Demaurex N, Lanzavecchia A, Fransen J, Figdor CG, Piguet V, van Kooyk Y.

J Immunol. 2002 Mar 1;168(5):2118-26.


Viral piracy: HIV-1 targets dendritic cells for transmission.

Lekkerkerker AN, van Kooyk Y, Geijtenbeek TB.

Curr HIV Res. 2006 Apr;4(2):169-76. Review.


Subset of DC-SIGN(+) dendritic cells in human blood transmits HIV-1 to T lymphocytes.

Engering A, Van Vliet SJ, Geijtenbeek TB, Van Kooyk Y.

Blood. 2002 Sep 1;100(5):1780-6.


A mouse C kappa-specific T cell clone indicates that DC-SIGN is an efficient target for antibody-mediated delivery of T cell epitopes for MHC class II presentation.

Schjetne KW, Thompson KM, Aarvak T, Fleckenstein B, Sollid LM, Bogen B.

Int Immunol. 2002 Dec;14(12):1423-30.


DC-SIGN: escape mechanism for pathogens.

van Kooyk Y, Geijtenbeek TB.

Nat Rev Immunol. 2003 Sep;3(9):697-709. Review.


Efficient capture of antibody neutralized HIV-1 by cells expressing DC-SIGN and transfer to CD4+ T lymphocytes.

van Montfort T, Nabatov AA, Geijtenbeek TB, Pollakis G, Paxton WA.

J Immunol. 2007 Mar 1;178(5):3177-85.


Uptake and presentation of hepatitis C virus-like particles by human dendritic cells.

Barth H, Ulsenheimer A, Pape GR, Diepolder HM, Hoffmann M, Neumann-Haefelin C, Thimme R, Henneke P, Klein R, Paranhos-Baccalà G, Depla E, Liang TJ, Blum HE, Baumert TF.

Blood. 2005 May 1;105(9):3605-14. Epub 2005 Jan 18.


Infection of dendritic cells (DCs), not DC-SIGN-mediated internalization of human immunodeficiency virus, is required for long-term transfer of virus to T cells.

Burleigh L, Lozach PY, Schiffer C, Staropoli I, Pezo V, Porrot F, Canque B, Virelizier JL, Arenzana-Seisdedos F, Amara A.

J Virol. 2006 Mar;80(6):2949-57.


A fatal attraction: Mycobacterium tuberculosis and HIV-1 target DC-SIGN to escape immune surveillance.

van Kooyk Y, Appelmelk B, Geijtenbeek TB.

Trends Mol Med. 2003 Apr;9(4):153-9. Review.


Extensive repertoire of membrane-bound and soluble dendritic cell-specific ICAM-3-grabbing nonintegrin 1 (DC-SIGN1) and DC-SIGN2 isoforms. Inter-individual variation in expression of DC-SIGN transcripts.

Mummidi S, Catano G, Lam L, Hoefle A, Telles V, Begum K, Jimenez F, Ahuja SS, Ahuja SK.

J Biol Chem. 2001 Aug 31;276(35):33196-212. Epub 2001 May 3.


The dendritic cell-specific C-type lectin DC-SIGN is a receptor for Schistosoma mansoni egg antigens and recognizes the glycan antigen Lewis x.

van Die I, van Vliet SJ, Nyame AK, Cummings RD, Bank CM, Appelmelk B, Geijtenbeek TB, van Kooyk Y.

Glycobiology. 2003 Jun;13(6):471-8. Epub 2003 Feb 20.


MHC-I-restricted presentation of HIV-1 virion antigens without viral replication.

Buseyne F, Le Gall S, Boccaccio C, Abastado JP, Lifson JD, Arthur LO, Rivière Y, Heard JM, Schwartz O.

Nat Med. 2001 Mar;7(3):344-9.


A dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin (DC-SIGN)-related protein is highly expressed on human liver sinusoidal endothelial cells and promotes HIV-1 infection.

Bashirova AA, Geijtenbeek TB, van Duijnhoven GC, van Vliet SJ, Eilering JB, Martin MP, Wu L, Martin TD, Viebig N, Knolle PA, KewalRamani VN, van Kooyk Y, Carrington M.

J Exp Med. 2001 Mar 19;193(6):671-8.


Dendritic cells and HIV-specific CD4+ T cells: HIV antigen presentation, T-cell activation, and viral transfer.

Moris A, Pajot A, Blanchet F, Guivel-Benhassine F, Salcedo M, Schwartz O.

Blood. 2006 Sep 1;108(5):1643-51. Epub 2006 May 4.


Targeting DC-SIGN via its neck region leads to prolonged antigen residence in early endosomes, delayed lysosomal degradation, and cross-presentation.

Tacken PJ, Ginter W, Berod L, Cruz LJ, Joosten B, Sparwasser T, Figdor CG, Cambi A.

Blood. 2011 Oct 13;118(15):4111-9. doi: 10.1182/blood-2011-04-346957. Epub 2011 Aug 22.

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