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Items: 1 to 20 of 95

1.

The Chfr mitotic checkpoint protein functions with Ubc13-Mms2 to form Lys63-linked polyubiquitin chains.

Bothos J, Summers MK, Venere M, Scolnick DM, Halazonetis TD.

Oncogene. 2003 Oct 16;22(46):7101-7.

PMID:
14562038
2.

Yeast Chfr homologs retard cell cycle at G1 and G2/M via Ubc4 and Ubc13/Mms2-dependent ubiquitination.

Loring GL, Christensen KC, Gerber SA, Brenner C.

Cell Cycle. 2008 Jan 1;7(1):96-105. Epub 2007 Oct 2.

3.

Chfr regulates a mitotic stress pathway through its RING-finger domain with ubiquitin ligase activity.

Chaturvedi P, Sudakin V, Bobiak ML, Fisher PW, Mattern MR, Jablonski SA, Hurle MR, Zhu Y, Yen TJ, Zhou BB.

Cancer Res. 2002 Mar 15;62(6):1797-801.

4.

Mms2-Ubc13 covalently bound to ubiquitin reveals the structural basis of linkage-specific polyubiquitin chain formation.

Eddins MJ, Carlile CM, Gomez KM, Pickart CM, Wolberger C.

Nat Struct Mol Biol. 2006 Oct;13(10):915-20. Epub 2006 Sep 17.

PMID:
16980971
6.

Distinct regulation of Ubc13 functions by the two ubiquitin-conjugating enzyme variants Mms2 and Uev1A.

Andersen PL, Zhou H, Pastushok L, Moraes T, McKenna S, Ziola B, Ellison MJ, Dixit VM, Xiao W.

J Cell Biol. 2005 Aug 29;170(5):745-55.

7.

The checkpoint protein Chfr is a ligase that ubiquitinates Plk1 and inhibits Cdc2 at the G2 to M transition.

Kang D, Chen J, Wong J, Fang G.

J Cell Biol. 2002 Jan 21;156(2):249-59. Epub 2002 Jan 21.

8.

Deubiquitination of Chfr, a checkpoint protein, by USP7/HAUSP regulates its stability and activity.

Oh YM, Yoo SJ, Seol JH.

Biochem Biophys Res Commun. 2007 Jun 8;357(3):615-9. Epub 2007 Apr 9.

PMID:
17442268
9.
10.

In vitro assembly and recognition of Lys-63 polyubiquitin chains.

Hofmann RM, Pickart CM.

J Biol Chem. 2001 Jul 27;276(30):27936-43. Epub 2001 May 21.

11.

Arabidopsis thaliana UBC13: implication of error-free DNA damage tolerance and Lys63-linked polyubiquitylation in plants.

Wen R, Newton L, Li G, Wang H, Xiao W.

Plant Mol Biol. 2006 May;61(1-2):241-53.

PMID:
16786304
12.

A single Mms2 "key" residue insertion into a Ubc13 pocket determines the interface specificity of a human Lys63 ubiquitin conjugation complex.

Pastushok L, Moraes TF, Ellison MJ, Xiao W.

J Biol Chem. 2005 May 6;280(18):17891-900. Epub 2005 Mar 4.

13.

Noncovalent interaction between ubiquitin and the human DNA repair protein Mms2 is required for Ubc13-mediated polyubiquitination.

McKenna S, Spyracopoulos L, Moraes T, Pastushok L, Ptak C, Xiao W, Ellison MJ.

J Biol Chem. 2001 Oct 26;276(43):40120-6. Epub 2001 Aug 14.

14.

Molecular insights into polyubiquitin chain assembly: crystal structure of the Mms2/Ubc13 heterodimer.

VanDemark AP, Hofmann RM, Tsui C, Pickart CM, Wolberger C.

Cell. 2001 Jun 15;105(6):711-20.

15.
16.

Nuclear localization of Chfr is crucial for its checkpoint function.

Kwon YE, Kim YS, Oh YM, Seol JH.

Mol Cells. 2009 Mar 31;27(3):359-63. doi: 10.1007/s10059-009-0046-7. Epub 2009 Mar 19.

17.

Roles of mouse UBC13 in DNA postreplication repair and Lys63-linked ubiquitination.

Ashley C, Pastushok L, McKenna S, Ellison MJ, Xiao W.

Gene. 2002 Feb 20;285(1-2):183-91.

PMID:
12039045
18.

TOPK and PTEN participate in CHFR mediated mitotic checkpoint.

Shinde SR, Gangula NR, Kavela S, Pandey V, Maddika S.

Cell Signal. 2013 Dec;25(12):2511-7. doi: 10.1016/j.cellsig.2013.08.013. Epub 2013 Sep 3.

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