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Gfi-1 oncoproteins in hematopoiesis.

Duan Z, Horwitz M.

Hematology. 2003 Oct;8(5):339-44. Review.


Erythroid expansion mediated by the Gfi-1B zinc finger protein: role in normal hematopoiesis.

Osawa M, Yamaguchi T, Nakamura Y, Kaneko S, Onodera M, Sawada K, Jegalian A, Wu H, Nakauchi H, Iwama A.

Blood. 2002 Oct 15;100(8):2769-77.


Gfi-1B plays a critical role in terminal differentiation of normal and transformed erythroid progenitor cells.

Garçon L, Lacout C, Svinartchouk F, Le Couédic JP, Villeval JL, Vainchenker W, Duménil D.

Blood. 2005 Feb 15;105(4):1448-55. Epub 2004 Oct 26.


Distinct, strict requirements for Gfi-1b in adult bone marrow red cell and platelet generation.

Foudi A, Kramer DJ, Qin J, Ye D, Behlich AS, Mordecai S, Preffer FI, Amzallag A, Ramaswamy S, Hochedlinger K, Orkin SH, Hock H.

J Exp Med. 2014 May 5;211(5):909-27. doi: 10.1084/jem.20131065. Epub 2014 Apr 7.


GATA-1 mediates auto-regulation of Gfi-1B transcription in K562 cells.

Huang DY, Kuo YY, Chang ZF.

Nucleic Acids Res. 2005 Sep 21;33(16):5331-42. Print 2005.


Gfi-1B controls human erythroid and megakaryocytic differentiation by regulating TGF-beta signaling at the bipotent erythro-megakaryocytic progenitor stage.

Randrianarison-Huetz V, Laurent B, Bardet V, Blobe GC, Huetz F, Duménil D.

Blood. 2010 Apr 8;115(14):2784-95. doi: 10.1182/blood-2009-09-241752. Epub 2010 Feb 2.


GATA-1 and NF-Y cooperate to mediate erythroid-specific transcription of Gfi-1B gene.

Huang DY, Kuo YY, Lai JS, Suzuki Y, Sugano S, Chang ZF.

Nucleic Acids Res. 2004 Jul 27;32(13):3935-46. Print 2004.


The transcriptional repressor GFI-1 antagonizes PU.1 activity through protein-protein interaction.

Dahl R, Iyer SR, Owens KS, Cuylear DD, Simon MC.

J Biol Chem. 2007 Mar 2;282(9):6473-83. Epub 2006 Dec 31.


A short Gfi-1B isoform controls erythroid differentiation by recruiting the LSD1-CoREST complex through the dimethylation of its SNAG domain.

Laurent B, Randrianarison-Huetz V, Frisan E, Andrieu-Soler C, Soler E, Fontenay M, Dusanter-Fourt I, Duménil D.

J Cell Sci. 2012 Feb 15;125(Pt 4):993-1002. doi: 10.1242/jcs.095877. Epub 2012 Mar 7.


The Gfi-1B proto-oncoprotein represses p21WAF1 and inhibits myeloid cell differentiation.

Tong B, Grimes HL, Yang TY, Bear SE, Qin Z, Du K, El-Deiry WS, Tsichlis PN.

Mol Cell Biol. 1998 May;18(5):2462-73.


Gene profiling of growth factor independence 1B gene (Gfi-1B) in leukemic cells.

Koldehoff M, Zakrzewski JL, Klein-Hitpass L, Beelen DW, Elmaagacli AH.

Int J Hematol. 2008 Jan;87(1):39-47. doi: 10.1007/s12185-007-0013-z. Epub 2007 Dec 6.


Gfi-1: another piece in the HSC puzzle.

Cellot S, Sauvageau G.

Trends Immunol. 2005 Feb;26(2):68-71. No abstract available.


Zinc finger protein GFI-1 has low oncogenic potential but cooperates strongly with pim and myc genes in T-cell lymphomagenesis.

Schmidt T, Karsunky H, Gau E, Zevnik B, Elsässer HP, Möröy T.

Oncogene. 1998 Nov 19;17(20):2661-7.


Gfi-1B promoter remains associated with active chromatin marks throughout erythroid differentiation of human primary progenitor cells.

Laurent B, Randrianarison-Huetz V, Kadri Z, Roméo PH, Porteu F, Duménil D.

Stem Cells. 2009 Sep;27(9):2153-62. doi: 10.1002/stem.151.


Gfi-1 attaches to the nuclear matrix, associates with ETO (MTG8) and histone deacetylase proteins, and represses transcription using a TSA-sensitive mechanism.

McGhee L, Bryan J, Elliott L, Grimes HL, Kazanjian A, Davis JN, Meyers S.

J Cell Biochem. 2003 Aug 1;89(5):1005-18.


Targets of the transcriptional repressor oncoprotein Gfi-1.

Duan Z, Horwitz M.

Proc Natl Acad Sci U S A. 2003 May 13;100(10):5932-7. Epub 2003 Apr 29. Erratum in: Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):16134.

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