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Items: 1 to 20 of 177

1.

The SAP and SLAM families in immune responses and X-linked lymphoproliferative disease.

Engel P, Eck MJ, Terhorst C.

Nat Rev Immunol. 2003 Oct;3(10):813-21. Review.

PMID:
14523387
2.

SAP couples Fyn to SLAM immune receptors.

Chan B, Lanyi A, Song HK, Griesbach J, Simarro-Grande M, Poy F, Howie D, Sumegi J, Terhorst C, Eck MJ.

Nat Cell Biol. 2003 Feb;5(2):155-60.

PMID:
12545174
3.

Regulation of SLAM-mediated signal transduction by SAP, the X-linked lymphoproliferative gene product.

Latour S, Gish G, Helgason CD, Humphries RK, Pawson T, Veillette A.

Nat Immunol. 2001 Aug;2(8):681-90.

PMID:
11477403
4.
5.

Distinct interactions of the X-linked lymphoproliferative syndrome gene product SAP with cytoplasmic domains of members of the CD2 receptor family.

Lewis J, Eiben LJ, Nelson DL, Cohen JI, Nichols KE, Ochs HD, Notarangelo LD, Duckett CS.

Clin Immunol. 2001 Jul;100(1):15-23.

PMID:
11414741
6.

The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM.

Sayos J, Wu C, Morra M, Wang N, Zhang X, Allen D, van Schaik S, Notarangelo L, Geha R, Roncarolo MG, Oettgen H, De Vries JE, Aversa G, Terhorst C.

Nature. 1998 Oct 1;395(6701):462-9.

PMID:
9774102
7.

Potential pathways for regulation of NK and T cell responses: differential X-linked lymphoproliferative syndrome gene product SAP interactions with SLAM and 2B4.

Sayós J, Nguyen KB, Wu C, Stepp SE, Howie D, Schatzle JD, Kumar V, Biron CA, Terhorst C.

Int Immunol. 2000 Dec;12(12):1749-57.

PMID:
11099315
8.

The gene defective in X-linked lymphoproliferative disease controls T cell dependent immune surveillance against Epstein-Barr virus.

Howie D, Sayos J, Terhorst C, Morra M.

Curr Opin Immunol. 2000 Aug;12(4):474-8. Review.

PMID:
10899030
9.

Disease-causing SAP mutants are defective in ligand binding and protein folding.

Li C, Iosef C, Jia CY, Gkourasas T, Han VK, Shun-Cheng Li S.

Biochemistry. 2003 Dec 23;42(50):14885-92.

PMID:
14674764
10.

Molecular dissection of 2B4 signaling: implications for signal transduction by SLAM-related receptors.

Chen R, Relouzat F, Roncagalli R, Aoukaty A, Tan R, Latour S, Veillette A.

Mol Cell Biol. 2004 Jun;24(12):5144-56.

11.

Novel mode of ligand binding by the SH2 domain of the human XLP disease gene product SAP/SH2D1A.

Li SC, Gish G, Yang D, Coffey AJ, Forman-Kay JD, Ernberg I, Kay LE, Pawson T.

Curr Biol. 1999 Dec 2;9(23):1355-62.

13.

Molecular and cellular pathogenesis of X-linked lymphoproliferative disease.

Nichols KE, Ma CS, Cannons JL, Schwartzberg PL, Tangye SG.

Immunol Rev. 2005 Feb;203:180-99. Review.

PMID:
15661030
14.
15.

SAP mediates specific cytotoxic T-cell functions in X-linked lymphoproliferative disease.

Sharifi R, Sinclair JC, Gilmour KC, Arkwright PD, Kinnon C, Thrasher AJ, Gaspar HB.

Blood. 2004 May 15;103(10):3821-7. Epub 2004 Jan 15.

16.

Molecular and immunological basis of X-linked lymphoproliferative disease.

Latour S, Veillette A.

Immunol Rev. 2003 Apr;192:212-24. Review.

PMID:
12670406
17.

Importance and mechanism of 'switch' function of SAP family adapters.

Veillette A, Dong Z, Pérez-Quintero LA, Zhong MC, Cruz-Munoz ME.

Immunol Rev. 2009 Nov;232(1):229-39. doi: 10.1111/j.1600-065X.2009.00824.x.

PMID:
19909367
18.

Signaling lymphocytic activation molecule (SLAM)/SLAM-associated protein pathway regulates human B-cell tolerance.

Menard L, Cantaert T, Chamberlain N, Tangye SG, Riminton S, Church JA, Klion A, Cunningham-Rundles C, Nichols KE, Meffre E.

J Allergy Clin Immunol. 2014 Apr;133(4):1149-61. doi: 10.1016/j.jaci.2013.10.051. Epub 2013 Dec 25.

19.

SAP: natural inhibitor or grand SLAM of T cell activation?

Nichols KE, Koretzky GA, June CH.

Nat Immunol. 2001 Aug;2(8):665-6. No abstract available.

PMID:
11477397
20.

Crystal structures of the XLP protein SAP reveal a class of SH2 domains with extended, phosphotyrosine-independent sequence recognition.

Poy F, Yaffe MB, Sayos J, Saxena K, Morra M, Sumegi J, Cantley LC, Terhorst C, Eck MJ.

Mol Cell. 1999 Oct;4(4):555-61.

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