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Items: 1 to 20 of 91

1.

Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis.

Lee EY, Chang CY, Hu N, Wang YC, Lai CC, Herrup K, Lee WH, Bradley A.

Nature. 1992 Sep 24;359(6393):288-94.

PMID:
1406932
2.

Requirement for a functional Rb-1 gene in murine development.

Clarke AR, Maandag ER, van Roon M, van der Lugt NM, van der Valk M, Hooper ML, Berns A, te Riele H.

Nature. 1992 Sep 24;359(6393):328-30.

PMID:
1406937
3.

Effects of an Rb mutation in the mouse.

Jacks T, Fazeli A, Schmitt EM, Bronson RT, Goodell MA, Weinberg RA.

Nature. 1992 Sep 24;359(6393):295-300.

PMID:
1406933
4.

Retinoblastoma gene promoter directs transgene expression exclusively to the nervous system.

Jiang Z, Guo Z, Saad FA, Ellis J, Zacksenhaus E.

J Biol Chem. 2001 Jan 5;276(1):593-600.

5.

Cell-autonomous and non-cell-autonomous functions of the Rb tumor suppressor in developing central nervous system.

Lipinski MM, Macleod KF, Williams BO, Mullaney TL, Crowley D, Jacks T.

EMBO J. 2001 Jul 2;20(13):3402-13.

6.

Targeted disruption of the GATA3 gene causes severe abnormalities in the nervous system and in fetal liver haematopoiesis.

Pandolfi PP, Roth ME, Karis A, Leonard MW, Dzierzak E, Grosveld FG, Engel JD, Lindenbaum MH.

Nat Genet. 1995 Sep;11(1):40-4.

PMID:
7550312
7.

Caspase 3 deficiency rescues peripheral nervous system defect in retinoblastoma nullizygous mice.

Simpson MT, MacLaurin JG, Xu D, Ferguson KL, Vanderluit JL, Davoli MA, Roy S, Nicholson DW, Robertson GS, Park DS, Slack RS.

J Neurosci. 2001 Sep 15;21(18):7089-98.

8.

Id2 is a retinoblastoma protein target and mediates signalling by Myc oncoproteins.

Lasorella A, Noseda M, Beyna M, Yokota Y, Iavarone A.

Nature. 2000 Oct 5;407(6804):592-8. Erratum in: Nature 2000 Nov 23;408(6811):498.

9.

Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos.

Tsai KY, Hu Y, Macleod KF, Crowley D, Yamasaki L, Jacks T.

Mol Cell. 1998 Sep;2(3):293-304.

10.

Targeted disruption of p107: functional overlap between p107 and Rb.

Lee MH, Williams BO, Mulligan G, Mukai S, Bronson RT, Dyson N, Harlow E, Jacks T.

Genes Dev. 1996 Jul 1;10(13):1621-32.

11.

Quantitative effects of the retinoblastoma gene on mouse development and tissue-specific tumorigenesis.

Chang CY, Riley DJ, Lee EY, Lee WH.

Cell Growth Differ. 1993 Dec;4(12):1057-64.

12.

Expression of the retinoblastoma family of tumor suppressors during murine embryonic orofacial development.

Leezer JL, Hackmiller RC, Greene RM, Pisano MM.

Orthod Craniofac Res. 2003 Feb;6(1):32-47.

PMID:
12627794
13.

Complementation mapping of skeletal and central nervous system abnormalities in mice of the piebald deletion complex.

O'Brien TP, Metallinos DL, Chen H, Shin MK, Tilghman SM.

Genetics. 1996 May;143(1):447-61.

14.

The molecular basis of cancer suppression by the retinoblastoma gene.

Lee WH.

Princess Takamatsu Symp. 1989;20:159-70.

PMID:
2488231
15.

The retinoblastoma gene family is differentially expressed during embryogenesis.

Jiang Z, Zacksenhaus E, Gallie BL, Phillips RA.

Oncogene. 1997 Apr 17;14(15):1789-97.

16.

Strain-dependent embryonic lethality in mice lacking the retinoblastoma-related p130 gene.

LeCouter JE, Kablar B, Whyte PF, Ying C, Rudnicki MA.

Development. 1998 Dec;125(23):4669-79.

17.
18.

Rescue of embryonic epithelium reveals that the homozygous deletion of the retinoblastoma gene confers growth factor independence and immortality but does not influence epithelial differentiation or tissue morphogenesis.

Day KC, McCabe MT, Zhao X, Wang Y, Davis JN, Phillips J, Von Geldern M, Ried T, KuKuruga MA, Cunha GR, Hayward SW, Day ML.

J Biol Chem. 2002 Nov 15;277(46):44475-84. Epub 2002 Aug 20.

19.

Paternal transmission of the mouse Thp mutation is lethal in some genetic backgrounds.

Rogers I, Okano K, Varmuza S.

Dev Genet. 1997;20(1):23-8.

PMID:
9094208
20.

Embryonic lethality and impairment of haematopoiesis in mice heterozygous for an AML1-ETO fusion gene.

Yergeau DA, Hetherington CJ, Wang Q, Zhang P, Sharpe AH, Binder M, MarĂ­n-Padilla M, Tenen DG, Speck NA, Zhang DE.

Nat Genet. 1997 Mar;15(3):303-6.

PMID:
9054947

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