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Items: 1 to 20 of 126

1.

cAMP promotes pancreatic beta-cell survival via CREB-mediated induction of IRS2.

Jhala US, Canettieri G, Screaton RA, Kulkarni RN, Krajewski S, Reed J, Walker J, Lin X, White M, Montminy M.

Genes Dev. 2003 Jul 1;17(13):1575-80.

2.

Exendin-4 uses Irs2 signaling to mediate pancreatic beta cell growth and function.

Park S, Dong X, Fisher TL, Dunn S, Omer AK, Weir G, White MF.

J Biol Chem. 2006 Jan 13;281(2):1159-68. Epub 2005 Nov 4.

3.
5.

Involvement of cAMP response element-binding protein in the regulation of cell proliferation and the prolactin promoter of lactotrophs in primary culture.

Ishida M, Mitsui T, Yamakawa K, Sugiyama N, Takahashi W, Shimura H, Endo T, Kobayashi T, Arita J.

Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1529-37. Epub 2007 Oct 9.

7.

Calcineurin signaling regulates human islet {beta}-cell survival.

Soleimanpour SA, Crutchlow MF, Ferrari AM, Raum JC, Groff DN, Rankin MM, Liu C, De León DD, Naji A, Kushner JA, Stoffers DA.

J Biol Chem. 2010 Dec 17;285(51):40050-9. doi: 10.1074/jbc.M110.154955. Epub 2010 Oct 13.

8.

Cyclic AMP-dependent activation of the proenkephalin gene requires phosphorylation of CREB at serine-133 and a Src-related kinase.

Kobierski LA, Wong AE, Srivastava S, Borsook D, Hyman SE.

J Neurochem. 1999 Jul;73(1):129-38.

9.

Nitric oxide mediates the survival action of IGF-1 and insulin in pancreatic beta cells.

Cahuana GM, Tejedo JR, Hmadcha A, Ramírez R, Cuesta AL, Soria B, Martin F, Bedoya FJ.

Cell Signal. 2008 Feb;20(2):301-10. Epub 2007 Oct 12.

PMID:
18023142
10.
11.

Glucagon promotes cAMP-response element-binding protein phosphorylation via activation of ERK1/2 in MIN6 cell line and isolated islets of Langerhans.

Dalle S, Longuet C, Costes S, Broca C, Faruque O, Fontés G, Hani EH, Bataille D.

J Biol Chem. 2004 May 7;279(19):20345-55. Epub 2004 Feb 26.

12.

Differential activation of protein kinase B and p70(S6)K by glucose and insulin-like growth factor 1 in pancreatic beta-cells (INS-1).

Dickson LM, Lingohr MK, McCuaig J, Hugl SR, Snow L, Kahn BB, Myers MG Jr, Rhodes CJ.

J Biol Chem. 2001 Jun 15;276(24):21110-20. Epub 2001 Mar 27.

13.
14.

mTOR links incretin signaling to HIF induction in pancreatic beta cells.

Van de Velde S, Hogan MF, Montminy M.

Proc Natl Acad Sci U S A. 2011 Oct 11;108(41):16876-82. doi: 10.1073/pnas.1114228108. Epub 2011 Sep 26.

15.

Noncanonical activation of Akt/protein kinase B in {beta}-cells by the incretin hormone glucose-dependent insulinotropic polypeptide.

Widenmaier SB, Sampaio AV, Underhill TM, McIntosh CH.

J Biol Chem. 2009 Apr 17;284(16):10764-73. doi: 10.1074/jbc.M809116200. Epub 2009 Feb 20.

16.

Small molecule kaempferol modulates PDX-1 protein expression and subsequently promotes pancreatic β-cell survival and function via CREB.

Zhang Y, Zhen W, Maechler P, Liu D.

J Nutr Biochem. 2013 Apr;24(4):638-46. doi: 10.1016/j.jnutbio.2012.03.008. Epub 2012 Jul 21.

17.

Obestatin promotes survival of pancreatic beta-cells and human islets and induces expression of genes involved in the regulation of beta-cell mass and function.

Granata R, Settanni F, Gallo D, Trovato L, Biancone L, Cantaluppi V, Nano R, Annunziata M, Campiglia P, Arnoletti E, Ghè C, Volante M, Papotti M, Muccioli G, Ghigo E.

Diabetes. 2008 Apr;57(4):967-79. Epub 2007 Dec 27.

18.

Dual role of the coactivator TORC2 in modulating hepatic glucose output and insulin signaling.

Canettieri G, Koo SH, Berdeaux R, Heredia J, Hedrick S, Zhang X, Montminy M.

Cell Metab. 2005 Nov;2(5):331-8.

19.

Identification of glucagon-like peptide-2 (GLP-2)-activated signaling pathways in baby hamster kidney fibroblasts expressing the rat GLP-2 receptor.

Yusta B, Somwar R, Wang F, Munroe D, Grinstein S, Klip A, Drucker DJ.

J Biol Chem. 1999 Oct 22;274(43):30459-67.

20.

Activation of IRS-2-mediated signal transduction by IGF-1, but not TGF-alpha or EGF, augments pancreatic beta-cell proliferation.

Lingohr MK, Dickson LM, McCuaig JF, Hugl SR, Twardzik DR, Rhodes CJ.

Diabetes. 2002 Apr;51(4):966-76.

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