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Items: 1 to 20 of 204

1.

Antidepressant and anxiolytic-like effects in mice lacking the group III metabotropic glutamate receptor mGluR7.

Cryan JF, Kelly PH, Neijt HC, Sansig G, Flor PJ, van Der Putten H.

Eur J Neurosci. 2003 Jun;17(11):2409-17.

PMID:
12814372
2.

Concomitant deficits in working memory and fear extinction are functionally dissociated from reduced anxiety in metabotropic glutamate receptor 7-deficient mice.

Callaerts-Vegh Z, Beckers T, Ball SM, Baeyens F, Callaerts PF, Cryan JF, Molnar E, D'Hooge R.

J Neurosci. 2006 Jun 14;26(24):6573-82.

3.

Increased measures of anxiety and weight gain in mice lacking the group III metabotropic glutamate receptor mGluR8.

Duvoisin RM, Zhang C, Pfankuch TF, O'Connor H, Gayet-Primo J, Quraishi S, Raber J.

Eur J Neurosci. 2005 Jul;22(2):425-36.

PMID:
16045496
4.

Metabotropic glutamate receptor subtype 7 ablation causes dysregulation of the HPA axis and increases hippocampal BDNF protein levels: implications for stress-related psychiatric disorders.

Mitsukawa K, Mombereau C, Lötscher E, Uzunov DP, van der Putten H, Flor PJ, Cryan JF.

Neuropsychopharmacology. 2006 Jun;31(6):1112-22.

5.

Behavioral profile of P2X7 receptor knockout mice in animal models of depression and anxiety: relevance for neuropsychiatric disorders.

Basso AM, Bratcher NA, Harris RR, Jarvis MF, Decker MW, Rueter LE.

Behav Brain Res. 2009 Mar 2;198(1):83-90. doi: 10.1016/j.bbr.2008.10.018. Epub 2008 Oct 18.

PMID:
18996151
6.

Activation of the mGlu7 receptor elicits antidepressant-like effects in mice.

Palucha A, Klak K, Branski P, van der Putten H, Flor PJ, Pilc A.

Psychopharmacology (Berl). 2007 Nov;194(4):555-62. Epub 2007 Jul 12.

PMID:
17622518
7.

Enhanced anxiety, depressive-like behaviour and impaired recognition memory in mice with reduced expression of the vesicular glutamate transporter 1 (VGLUT1).

Tordera RM, Totterdell S, Wojcik SM, Brose N, Elizalde N, Lasheras B, Del Rio J.

Eur J Neurosci. 2007 Jan;25(1):281-90.

PMID:
17241289
8.

Altered depression-related behaviors and functional changes in the dorsal raphe nucleus of serotonin transporter-deficient mice.

Lira A, Zhou M, Castanon N, Ansorge MS, Gordon JA, Francis JH, Bradley-Moore M, Lira J, Underwood MD, Arango V, Kung HF, Hofer MA, Hen R, Gingrich JA.

Biol Psychiatry. 2003 Nov 15;54(10):960-71.

PMID:
14625138
9.

Metabotropic glutamate receptor subtype 7 ablation causes deficit in fear response and conditioned taste aversion.

Masugi M, Yokoi M, Shigemoto R, Muguruma K, Watanabe Y, Sansig G, van der Putten H, Nakanishi S.

J Neurosci. 1999 Feb 1;19(3):955-63.

10.

Mice lacking metabotropic glutamate receptor 4 do not show the motor stimulatory effect of ethanol.

Blednov YA, Walker D, Osterndorf-Kahanek E, Harris RA.

Alcohol. 2004 Oct-Nov;34(2-3):251-9.

PMID:
15902920
11.

WAY-200070, a selective agonist of estrogen receptor beta as a potential novel anxiolytic/antidepressant agent.

Hughes ZA, Liu F, Platt BJ, Dwyer JM, Pulicicchio CM, Zhang G, Schechter LE, Rosenzweig-Lipson S, Day M.

Neuropharmacology. 2008 Jun;54(7):1136-42. doi: 10.1016/j.neuropharm.2008.03.004. Epub 2008 Mar 18.

PMID:
18423777
12.

Altered anxiety and depression-related behaviour in mice lacking GABAB(2) receptor subunits.

Mombereau C, Kaupmann K, Gassmann M, Bettler B, van der Putten H, Cryan JF.

Neuroreport. 2005 Feb 28;16(3):307-10.

PMID:
15706241
13.

Genetic inactivation of the NMDA receptor NR2A subunit has anxiolytic- and antidepressant-like effects in mice.

Boyce-Rustay JM, Holmes A.

Neuropsychopharmacology. 2006 Nov;31(11):2405-14. Epub 2006 Feb 8.

14.

Anxiolytic- and antidepressant-like profile of a new CRF1 receptor antagonist, R278995/CRA0450.

Chaki S, Nakazato A, Kennis L, Nakamura M, Mackie C, Sugiura M, Vinken P, Ashton D, Langlois X, Steckler T.

Eur J Pharmacol. 2004 Feb 6;485(1-3):145-58.

PMID:
14757135
15.

Genetic and pharmacological evidence of a role for GABA(B) receptors in the modulation of anxiety- and antidepressant-like behavior.

Mombereau C, Kaupmann K, Froestl W, Sansig G, van der Putten H, Cryan JF.

Neuropsychopharmacology. 2004 Jun;29(6):1050-62.

16.

The neuropeptide Y Y1 receptor subtype is necessary for the anxiolytic-like effects of neuropeptide Y, but not the antidepressant-like effects of fluoxetine, in mice.

Karlsson RM, Choe JS, Cameron HA, Thorsell A, Crawley JN, Holmes A, Heilig M.

Psychopharmacology (Berl). 2008 Jan;195(4):547-57. Epub 2007 Sep 22.

PMID:
17891380
17.

Metabotropic glutamate receptor ligands as possible anxiolytic and antidepressant drugs.

Palucha A, Pilc A.

Pharmacol Ther. 2007 Jul;115(1):116-47. Epub 2007 May 13. Review.

PMID:
17582504
18.

Molecular basis for the differential agonist affinities of group III metabotropic glutamate receptors.

Rosemond E, Wang M, Yao Y, Storjohann L, Stormann T, Johnson EC, Hampson DR.

Mol Pharmacol. 2004 Oct;66(4):834-42. Epub 2004 Jul 1.

19.

Modulation of defensive responses and anxiety-like behaviors by group I metabotropic glutamate receptors located in the dorsolateral periaqueductal gray.

Lima VC, Molchanov ML, Aguiar DC, Campos AC, Guimarães FS.

Prog Neuropsychopharmacol Biol Psychiatry. 2008 Jan 1;32(1):178-85. Epub 2007 Aug 15.

PMID:
17804134
20.

Phosphodiesterase 10A inhibition is associated with locomotor and cognitive deficits and increased anxiety in mice.

Hebb AL, Robertson HA, Denovan-Wright EM.

Eur Neuropsychopharmacol. 2008 May;18(5):339-63. Epub 2007 Oct 29.

PMID:
17913473

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