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Items: 1 to 20 of 257

1.

Retinoic acid-induced growth arrest of MCF-7 cells involves the selective regulation of the IRS-1/PI 3-kinase/AKT pathway.

del Rincón SV, Rousseau C, Samanta R, Miller WH Jr.

Oncogene. 2003 May 29;22(22):3353-60.

PMID:
12776186
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Activation of IRS-2-mediated signal transduction by IGF-1, but not TGF-alpha or EGF, augments pancreatic beta-cell proliferation.

Lingohr MK, Dickson LM, McCuaig JF, Hugl SR, Twardzik DR, Rhodes CJ.

Diabetes. 2002 Apr;51(4):966-76.

6.

Interferon-dependent activation of the serine kinase PI 3'-kinase requires engagement of the IRS pathway but not the Stat pathway.

Uddin S, Majchrzak B, Wang PC, Modi S, Khan MK, Fish EN, Platanias LC.

Biochem Biophys Res Commun. 2000 Apr 2;270(1):158-62.

PMID:
10733921
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Insulin-like growth factor I receptor activity in human medulloblastomas.

Del Valle L, Enam S, Lassak A, Wang JY, Croul S, Khalili K, Reiss K.

Clin Cancer Res. 2002 Jun;8(6):1822-30.

10.

Regulation of insulin/insulin-like growth factor-1 signaling by proteasome-mediated degradation of insulin receptor substrate-2.

Rui L, Fisher TL, Thomas J, White MF.

J Biol Chem. 2001 Oct 26;276(43):40362-7. Epub 2001 Aug 23.

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Activation of the insulin-like growth factor 1 signaling pathway by the antiapoptotic agents aurintricarboxylic acid and evans blue.

Beery R, Haimsohn M, Wertheim N, Hemi R, Nir U, Karasik A, Kanety H, Geier A.

Endocrinology. 2001 Jul;142(7):3098-107.

PMID:
11416032
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Growth hormone induces cellular insulin resistance by uncoupling phosphatidylinositol 3-kinase and its downstream signals in 3T3-L1 adipocytes.

Takano A, Haruta T, Iwata M, Usui I, Uno T, Kawahara J, Ueno E, Sasaoka T, Kobayashi M.

Diabetes. 2001 Aug;50(8):1891-900.

16.

Inhibition of insulin-like growth factor-I receptor (IGF-IR) signaling and tumor cell growth by a fully human neutralizing anti-IGF-IR antibody.

Wang Y, Hailey J, Williams D, Wang Y, Lipari P, Malkowski M, Wang X, Xie L, Li G, Saha D, Ling WL, Cannon-Carlson S, Greenberg R, Ramos RA, Shields R, Presta L, Brams P, Bishop WR, Pachter JA.

Mol Cancer Ther. 2005 Aug;4(8):1214-21.

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PKCdelta and mTOR interact to regulate stress and IGF-I induced IRS-1 Ser312 phosphorylation in breast cancer cells.

Mingo-Sion AM, Ferguson HA, Koller E, Reyland ME, Van Den Berg CL.

Breast Cancer Res Treat. 2005 Jun;91(3):259-69.

PMID:
15952059

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