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Items: 1 to 20 of 489

1.

Bis(glutathionyl)spermine and other novel trypanothione analogues in Trypanosoma cruzi.

Ariyanayagam MR, Oza SL, Mehlert A, Fairlamb AH.

J Biol Chem. 2003 Jul 25;278(30):27612-9. Epub 2003 May 15.

2.

A single enzyme catalyses formation of Trypanothione from glutathione and spermidine in Trypanosoma cruzi.

Oza SL, Tetaud E, Ariyanayagam MR, Warnon SS, Fairlamb AH.

J Biol Chem. 2002 Sep 27;277(39):35853-61. Epub 2002 Jul 16.

3.

Properties of trypanothione synthetase from Trypanosoma brucei.

Oza SL, Ariyanayagam MR, Aitcheson N, Fairlamb AH.

Mol Biochem Parasitol. 2003 Sep;131(1):25-33.

PMID:
12967709
4.

Glutathionylation of trypanosomal thiol redox proteins.

Melchers J, Dirdjaja N, Ruppert T, Krauth-Siegel RL.

J Biol Chem. 2007 Mar 23;282(12):8678-94. Epub 2007 Jan 22.

5.
6.

Glyoxalase II of African trypanosomes is trypanothione-dependent.

Irsch T, Krauth-Siegel RL.

J Biol Chem. 2004 May 21;279(21):22209-17. Epub 2004 Feb 19.

7.

In vivo effects of difluoromethylornithine on trypanothione and polyamine levels in bloodstream forms of Trypanosoma brucei.

Fairlamb AH, Henderson GB, Bacchi CJ, Cerami A.

Mol Biochem Parasitol. 1987 Jun;24(2):185-91.

PMID:
3114634
8.

Trypanothione: a novel bis(glutathionyl)spermidine cofactor for glutathione reductase in trypanosomatids.

Fairlamb AH, Blackburn P, Ulrich P, Chait BT, Cerami A.

Science. 1985 Mar 22;227(4693):1485-7.

PMID:
3883489
9.

Biosynthesis of the trypanosomatid metabolite trypanothione: purification and characterization of trypanothione synthetase from Crithidia fasciculata.

Henderson GB, Yamaguchi M, Novoa L, Fairlamb AH, Cerami A.

Biochemistry. 1990 Apr 24;29(16):3924-9.

PMID:
2354163
10.

Polyamine and thiol metabolism in Trypanosoma granulosum: similarities with Trypanosoma cruzi.

Mastri C, Thorborn DE, Davies AJ, Ariyanayagam MR, Hunter KJ.

Biochem Biophys Res Commun. 2001 Apr 20;282(5):1177-82.

PMID:
11302739
11.

Entamoeba histolytica lacks trypanothione metabolism.

Ariyanayagam MR, Fairlamb AH.

Mol Biochem Parasitol. 1999 Sep 20;103(1):61-9.

PMID:
10514081
12.
13.

Polyamine derivatives as inhibitors of trypanothione reductase and assessment of their trypanocidal activities.

O'Sullivan MC, Zhou Q, Li Z, Durham TB, Rattendi D, Lane S, Bacchi CJ.

Bioorg Med Chem. 1997 Dec;5(12):2145-55.

PMID:
9459012
14.

Substrate specificity of the flavoprotein trypanothione disulfide reductase from Crithidia fasciculata.

Henderson GB, Fairlamb AH, Ulrich P, Cerami A.

Biochemistry. 1987 Jun 2;26(11):3023-7.

PMID:
3607007
15.

Ovothiol and trypanothione as antioxidants in trypanosomatids.

Ariyanayagam MR, Fairlamb AH.

Mol Biochem Parasitol. 2001 Jul;115(2):189-98.

PMID:
11420105
16.

Glutathione reductase turned into trypanothione reductase: structural analysis of an engineered change in substrate specificity.

Stoll VS, Simpson SJ, Krauth-Siegel RL, Walsh CT, Pai EF.

Biochemistry. 1997 May 27;36(21):6437-47.

PMID:
9174360
17.

Substrate specificity of trypanothione reductase.

Marsh IR, Bradley M.

Eur J Biochem. 1997 Feb 1;243(3):690-4.

18.

Polyamine metabolism in Leishmania: from arginine to trypanothione.

Colotti G, Ilari A.

Amino Acids. 2011 Feb;40(2):269-85. doi: 10.1007/s00726-010-0630-3. Epub 2010 May 29. Review.

PMID:
20512387
19.

Inhibiting effects of spermidine derivatives on Trypanosoma cruzi trypanothione reductase.

O'Sullivan MC, Dalrymple DM, Zhou Q.

J Enzyme Inhib. 1996 Oct;11(2):97-114.

PMID:
9204399
20.

Redox enzyme engineering: conversion of human glutathione reductase into a trypanothione reductase.

Bradley M, B├╝cheler US, Walsh CT.

Biochemistry. 1991 Jun 25;30(25):6124-7.

PMID:
2059620

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