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Items: 1 to 20 of 509

1.

RET/PTC (rearranged in transformation/papillary thyroid carcinomas) tyrosine kinase phosphorylates and activates phosphoinositide-dependent kinase 1 (PDK1): an alternative phosphatidylinositol 3-kinase-independent pathway to activate PDK1.

Kim DW, Hwang JH, Suh JM, Kim H, Song JH, Hwang ES, Hwang IY, Park KC, Chung HK, Kim JM, Park J, Hemmings BA, Shong M.

Mol Endocrinol. 2003 Jul;17(7):1382-94. Epub 2003 May 8.

PMID:
12738763
2.

Regulation of signal transducer and activator of transcription 1 (STAT1) and STAT1-dependent genes by RET/PTC (rearranged in transformation/papillary thyroid carcinoma) oncogenic tyrosine kinases.

Hwang ES, Kim DW, Hwang JH, Jung HS, Suh JM, Park YJ, Chung HK, Song JH, Park KC, Park SH, Yun HJ, Kim JM, Shong M.

Mol Endocrinol. 2004 Nov;18(11):2672-84. Epub 2004 Aug 5.

PMID:
15297606
3.

Activation of signal transducer and activator of transcription 3 by oncogenic RET/PTC (rearranged in transformation/papillary thyroid carcinoma) tyrosine kinase: roles in specific gene regulation and cellular transformation.

Hwang JH, Kim DW, Suh JM, Kim H, Song JH, Hwang ES, Park KC, Chung HK, Kim JM, Lee TH, Yu DY, Shong M.

Mol Endocrinol. 2003 Jun;17(6):1155-66. Epub 2003 Mar 13.

PMID:
12637586
4.

[Effect of papillary thyroid carcinoma related gene PTC1 on subcellular localization and function of ATM cell].

Tie Y, Mao JP, Liu B, Song Y, Dong Y, Sun ZX.

Ai Zheng. 2004 May;23(5):487-92. Chinese.

PMID:
15142440
5.

RET/PTC rearrangements in thyroid nodules: studies in irradiated and not irradiated, malignant and benign thyroid lesions in children and adults.

Elisei R, Romei C, Vorontsova T, Cosci B, Veremeychik V, Kuchinskaya E, Basolo F, Demidchik EP, Miccoli P, Pinchera A, Pacini F.

J Clin Endocrinol Metab. 2001 Jul;86(7):3211-6.

PMID:
11443191
6.

XB130, a tissue-specific adaptor protein that couples the RET/PTC oncogenic kinase to PI 3-kinase pathway.

Lodyga M, De Falco V, Bai XH, Kapus A, Melillo RM, Santoro M, Liu M.

Oncogene. 2009 Feb 19;28(7):937-49. doi: 10.1038/onc.2008.447. Epub 2008 Dec 8.

PMID:
19060924
7.

Conditional expression of RET/PTC induces a weak oncogenic drive in thyroid PCCL3 cells and inhibits thyrotropin action at multiple levels.

Wang J, Knauf JA, Basu S, Puxeddu E, Kuroda H, Santoro M, Fusco A, Fagin JA.

Mol Endocrinol. 2003 Jul;17(7):1425-36. Epub 2003 Apr 10.

PMID:
12690093
8.

Tumor suppressor LKB1 inhibits activation of signal transducer and activator of transcription 3 (STAT3) by thyroid oncogenic tyrosine kinase rearranged in transformation (RET)/papillary thyroid carcinoma (PTC).

Kim DW, Chung HK, Park KC, Hwang JH, Jo YS, Chung J, Kalvakolanu DV, Resta N, Shong M.

Mol Endocrinol. 2007 Dec;21(12):3039-49. Epub 2007 Aug 30.

PMID:
17761947
9.

Ret/PTC activation does not influence clinical and pathological features of adult papillary thyroid carcinomas.

Puxeddu E, Moretti S, Giannico A, Martinelli M, Marino C, Avenia N, Cristofani R, Farabi R, Reboldi G, Ribacchi R, Pontecorvi A, Santeusanio F.

Eur J Endocrinol. 2003 May;148(5):505-13.

10.

Modulatory role of phospholipase D in the activation of signal transducer and activator of transcription (STAT)-3 by thyroid oncogenic kinase RET/PTC.

Kim YR, Byun HS, Won M, Park KA, Kim JM, Choi BL, Lee H, Hong JH, Park J, Seok JH, Kim DW, Shong M, Park SK, Hur GM.

BMC Cancer. 2008 May 23;8:144. doi: 10.1186/1471-2407-8-144.

11.

Ras-mediated apoptosis of PC CL 3 rat thyroid cells induced by RET/PTC oncogenes.

Castellone MD, Cirafici AM, De Vita G, De Falco V, Malorni L, Tallini G, Fagin JA, Fusco A, Melillo RM, Santoro M.

Oncogene. 2003 Jan 16;22(2):246-55.

PMID:
12527893
12.

RET oncogene activation in papillary thyroid carcinoma.

Tallini G, Asa SL.

Adv Anat Pathol. 2001 Nov;8(6):345-54. Review.

PMID:
11707626
13.

Regulation of protein kinase B tyrosine phosphorylation by thyroid-specific oncogenic RET/PTC kinases.

Jung HS, Kim DW, Jo YS, Chung HK, Song JH, Park JS, Park KC, Park SH, Hwang JH, Jo KW, Shong M.

Mol Endocrinol. 2005 Nov;19(11):2748-59. Epub 2005 Jun 30.

PMID:
15994200
14.

Identification of the product of two oncogenic rearranged forms of the RET proto-oncogene in papillary thyroid carcinomas.

Lanzi C, Borrello MG, Bongarzone I, Migliazza A, Fusco A, Grieco M, Santoro M, Gambetta RA, Zunino F, Della Porta G, et al.

Oncogene. 1992 Nov;7(11):2189-94.

PMID:
1437145
15.

Real-time quantitative RT-PCR identifies distinct c-RET, RET/PTC1 and RET/PTC3 expression patterns in papillary thyroid carcinoma.

Rhoden KJ, Johnson C, Brandao G, Howe JG, Smith BR, Tallini G.

Lab Invest. 2004 Dec;84(12):1557-70.

16.

Ret oncogene signal transduction via a IRS-2/PI 3-kinase/PKB and a SHC/Grb-2 dependent pathway: possible implication for transforming activity in NIH3T3 cells.

Hennige AM, Lammers R, Arlt D, Höppner W, Strack V, Niederfellner G, Seif FJ, Häring HU, Kellerer M.

Mol Cell Endocrinol. 2000 Sep 25;167(1-2):69-76.

PMID:
11000521
17.

Tyrosines 1015 and 1062 are in vivo autophosphorylation sites in ret and ret-derived oncoproteins.

Salvatore D, Barone MV, Salvatore G, Melillo RM, Chiappetta G, Mineo A, Fenzi G, Vecchio G, Fusco A, Santoro M.

J Clin Endocrinol Metab. 2000 Oct;85(10):3898-907.

PMID:
11061555
18.

Assessment of RET/PTC oncogene activation and clonality in thyroid nodules with incomplete morphological evidence of papillary carcinoma: a search for the early precursors of papillary cancer.

Fusco A, Chiappetta G, Hui P, Garcia-Rostan G, Golden L, Kinder BK, Dillon DA, Giuliano A, Cirafici AM, Santoro M, Rosai J, Tallini G.

Am J Pathol. 2002 Jun;160(6):2157-67.

19.

Papillary thyroid carcinoma: 6 cases from 2 families with associated lymphocytic thyroiditis harbouring RET/PTC rearrangements.

Mechler C, Bounacer A, Suarez H, Saint Frison M, Magois C, Aillet G, Gaulier A.

Br J Cancer. 2001 Dec 14;85(12):1831-7.

20.

Expression of Ret/PTC1, -2, -3, -delta3 and -4 in German papillary thyroid carcinoma.

Mayr B, Pötter E, Goretzki P, Rüschoff J, Dietmaier W, Hoang-Vu C, Dralle H, Brabant G.

Br J Cancer. 1998 Mar;77(6):903-6.

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