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Items: 1 to 20 of 108

1.

Use of RNA interference-mediated gene silencing and adenoviral overexpression to elucidate the roles of AKT/protein kinase B isoforms in insulin actions.

Katome T, Obata T, Matsushima R, Masuyama N, Cantley LC, Gotoh Y, Kishi K, Shiota H, Ebina Y.

J Biol Chem. 2003 Jul 25;278(30):28312-23. Epub 2003 May 6.

2.

Requirement of atypical protein kinase clambda for insulin stimulation of glucose uptake but not for Akt activation in 3T3-L1 adipocytes.

Kotani K, Ogawa W, Matsumoto M, Kitamura T, Sakaue H, Hino Y, Miyake K, Sano W, Akimoto K, Ohno S, Kasuga M.

Mol Cell Biol. 1998 Dec;18(12):6971-82.

3.

Essential role of insulin receptor substrate-2 in insulin stimulation of Glut4 translocation and glucose uptake in brown adipocytes.

Fasshauer M, Klein J, Ueki K, Kriauciunas KM, Benito M, White MF, Kahn CR.

J Biol Chem. 2000 Aug 18;275(33):25494-501.

4.

Overexpression of SH2-containing inositol phosphatase 2 results in negative regulation of insulin-induced metabolic actions in 3T3-L1 adipocytes via its 5'-phosphatase catalytic activity.

Wada T, Sasaoka T, Funaki M, Hori H, Murakami S, Ishiki M, Haruta T, Asano T, Ogawa W, Ishihara H, Kobayashi M.

Mol Cell Biol. 2001 Mar;21(5):1633-46.

5.

Insulin signaling through Akt/protein kinase B analyzed by small interfering RNA-mediated gene silencing.

Jiang ZY, Zhou QL, Coleman KA, Chouinard M, Boese Q, Czech MP.

Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7569-74. Epub 2003 Jun 13.

6.

Membrane localization of 3-phosphoinositide-dependent protein kinase-1 stimulates activities of Akt and atypical protein kinase C but does not stimulate glucose transport and glycogen synthesis in 3T3-L1 adipocytes.

Egawa K, Maegawa H, Shi K, Nakamura T, Obata T, Yoshizaki T, Morino K, Shimizu S, Nishio Y, Suzuki E, Kashiwagi A.

J Biol Chem. 2002 Oct 11;277(41):38863-9. Epub 2002 Jul 29.

8.

Isoform-specific regulation of insulin-dependent glucose uptake by Akt/protein kinase B.

Bae SS, Cho H, Mu J, Birnbaum MJ.

J Biol Chem. 2003 Dec 5;278(49):49530-6. Epub 2003 Sep 30.

9.

Activation of the mammalian target of rapamycin pathway acutely inhibits insulin signaling to Akt and glucose transport in 3T3-L1 and human adipocytes.

Tremblay F, Gagnon A, Veilleux A, Sorisky A, Marette A.

Endocrinology. 2005 Mar;146(3):1328-37. Epub 2004 Dec 2.

PMID:
15576463
10.

Requirement for activation of the serine-threonine kinase Akt (protein kinase B) in insulin stimulation of protein synthesis but not of glucose transport.

Kitamura T, Ogawa W, Sakaue H, Hino Y, Kuroda S, Takata M, Matsumoto M, Maeda T, Konishi H, Kikkawa U, Kasuga M.

Mol Cell Biol. 1998 Jul;18(7):3708-17.

11.

Differing roles of Akt and serum- and glucocorticoid-regulated kinase in glucose metabolism, DNA synthesis, and oncogenic activity.

Sakoda H, Gotoh Y, Katagiri H, Kurokawa M, Ono H, Onishi Y, Anai M, Ogihara T, Fujishiro M, Fukushima Y, Abe M, Shojima N, Kikuchi M, Oka Y, Hirai H, Asano T.

J Biol Chem. 2003 Jul 11;278(28):25802-7. Epub 2003 May 6.

12.

Role of PDK1 in insulin-signaling pathway for glucose metabolism in 3T3-L1 adipocytes.

Yamada T, Katagiri H, Asano T, Tsuru M, Inukai K, Ono H, Kodama T, Kikuchi M, Oka Y.

Am J Physiol Endocrinol Metab. 2002 Jun;282(6):E1385-94.

13.

Maturation of the regulation of GLUT4 activity by p38 MAPK during L6 cell myogenesis.

Niu W, Huang C, Nawaz Z, Levy M, Somwar R, Li D, Bilan PJ, Klip A.

J Biol Chem. 2003 May 16;278(20):17953-62. Epub 2003 Mar 11.

14.

A role for protein kinase Bbeta/Akt2 in insulin-stimulated GLUT4 translocation in adipocytes.

Hill MM, Clark SF, Tucker DF, Birnbaum MJ, James DE, Macaulay SL.

Mol Cell Biol. 1999 Nov;19(11):7771-81.

15.

The role of Ca2+ in insulin-stimulated glucose transport in 3T3-L1 cells.

Whitehead JP, Molero JC, Clark S, Martin S, Meneilly G, James DE.

J Biol Chem. 2001 Jul 27;276(30):27816-24. Epub 2001 May 24.

16.

Requirement for 3-phosphoinositide-kependent dinase-1 (PDK-1) in insulin-induced glucose uptake in immortalized brown adipocytes.

Sakaue H, Nishizawa A, Ogawa W, Teshigawara K, Mori T, Takashima Y, Noda T, Kasuga M.

J Biol Chem. 2003 Oct 3;278(40):38870-4. Epub 2003 Jul 10.

17.

Akt2 phosphorylates Synip to regulate docking and fusion of GLUT4-containing vesicles.

Yamada E, Okada S, Saito T, Ohshima K, Sato M, Tsuchiya T, Uehara Y, Shimizu H, Mori M.

J Cell Biol. 2005 Mar 14;168(6):921-8. Epub 2005 Mar 7.

18.

Protein kinase B phosphorylation of PIKfyve regulates the trafficking of GLUT4 vesicles.

Berwick DC, Dell GC, Welsh GI, Heesom KJ, Hers I, Fletcher LM, Cooke FT, Tavaré JM.

J Cell Sci. 2004 Dec 1;117(Pt 25):5985-93. Epub 2004 Nov 16.

19.

Physiological role of Akt in insulin-stimulated translocation of GLUT4 in transfected rat adipose cells.

Cong LN, Chen H, Li Y, Zhou L, McGibbon MA, Taylor SI, Quon MJ.

Mol Endocrinol. 1997 Dec;11(13):1881-90.

PMID:
9415393
20.

The role of glycogen synthase kinase 3beta in insulin-stimulated glucose metabolism.

Summers SA, Kao AW, Kohn AD, Backus GS, Roth RA, Pessin JE, Birnbaum MJ.

J Biol Chem. 1999 Jun 18;274(25):17934-40.

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