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Items: 1 to 20 of 182

1.

Proteomic screen finds pSer/pThr-binding domain localizing Plk1 to mitotic substrates.

Elia AE, Cantley LC, Yaffe MB.

Science. 2003 Feb 21;299(5610):1228-31.

2.

Polo-box domains confer target specificity to the Polo-like kinase family.

van de Weerdt BC, Littler DR, Klompmaker R, Huseinovic A, Fish A, Perrakis A, Medema RH.

Biochim Biophys Acta. 2008 Jun;1783(6):1015-22. doi: 10.1016/j.bbamcr.2008.02.019. Epub 2008 Mar 5.

3.

The molecular basis for phosphodependent substrate targeting and regulation of Plks by the Polo-box domain.

Elia AE, Rellos P, Haire LF, Chao JW, Ivins FJ, Hoepker K, Mohammad D, Cantley LC, Smerdon SJ, Yaffe MB.

Cell. 2003 Oct 3;115(1):83-95.

4.

Computational analysis of phosphopeptide binding to the polo-box domain of the mitotic kinase PLK1 using molecular dynamics simulation.

Huggins DJ, McKenzie GJ, Robinson DD, Narváez AJ, Hardwick B, Roberts-Thomson M, Venkitaraman AR, Grant GH, Payne MC.

PLoS Comput Biol. 2010 Aug 12;6(8). pii: e1000880. doi: 10.1371/journal.pcbi.1000880.

5.

Signal transduction. Capturing polo kinase.

Silljé HH, Nigg EA.

Science. 2003 Feb 21;299(5610):1190-1. No abstract available.

PMID:
12595680
6.

Proteomic screening method for phosphopeptide motif binding proteins using peptide libraries.

Christofk HR, Wu N, Cantley LC, Asara JM.

J Proteome Res. 2011 Sep 2;10(9):4158-64. doi: 10.1021/pr200578n. Epub 2011 Aug 2.

7.

BRCT repeats as phosphopeptide-binding modules involved in protein targeting.

Manke IA, Lowery DM, Nguyen A, Yaffe MB.

Science. 2003 Oct 24;302(5645):636-9.

8.

Molecular and structural basis of polo-like kinase 1 substrate recognition: Implications in centrosomal localization.

García-Alvarez B, de Cárcer G, Ibañez S, Bragado-Nilsson E, Montoya G.

Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3107-12. Epub 2007 Feb 16.

9.

Identification of a consensus motif for Plk (Polo-like kinase) phosphorylation reveals Myt1 as a Plk1 substrate.

Nakajima H, Toyoshima-Morimoto F, Taniguchi E, Nishida E.

J Biol Chem. 2003 Jul 11;278(28):25277-80. Epub 2003 May 8.

10.

Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1.

Yun SM, Moulaei T, Lim D, Bang JK, Park JE, Shenoy SR, Liu F, Kang YH, Liao C, Soung NK, Lee S, Yoon DY, Lim Y, Lee DH, Otaka A, Appella E, McMahon JB, Nicklaus MC, Burke TR Jr, Yaffe MB, Wlodawer A, Lee KS.

Nat Struct Mol Biol. 2009 Aug;16(8):876-82. doi: 10.1038/nsmb.1628. Epub 2009 Jul 13. Erratum in: Nat Struct Mol Biol. 2011 Apr;18(4):516.

11.

Plk1 activation by Ste20-like kinase (Slk) phosphorylation and polo-box phosphopeptide binding assayed with the substrate translationally controlled tumor protein (TCTP).

Johnson TM, Antrobus R, Johnson LN.

Biochemistry. 2008 Mar 25;47(12):3688-96. doi: 10.1021/bi702134c. Epub 2008 Feb 26.

PMID:
18298087
12.

Mono-anionic phosphopeptides produced by unexpected histidine alkylation exhibit high Plk1 polo-box domain-binding affinities and enhanced antiproliferative effects in HeLa cells.

Qian WJ, Park JE, Lim D, Lai CC, Kelley JA, Park SY, Lee KW, Yaffe MB, Lee KS, Burke TR Jr.

Biopolymers. 2014 Nov;102(6):444-55. doi: 10.1002/bip.22569.

13.

Cyclin-dependent kinase (CDK) phosphorylation destabilizes somatic Wee1 via multiple pathways.

Watanabe N, Arai H, Iwasaki J, Shiina M, Ogata K, Hunter T, Osada H.

Proc Natl Acad Sci U S A. 2005 Aug 16;102(33):11663-8. Epub 2005 Aug 5.

14.

Different Plk1 functions show distinct dependencies on Polo-Box domain-mediated targeting.

Hanisch A, Wehner A, Nigg EA, Silljé HH.

Mol Biol Cell. 2006 Jan;17(1):448-59. Epub 2005 Nov 2.

15.

A polo match for Plk1.

Leung GC, Sicheri F.

Cell. 2003 Oct 3;115(1):3-4.

16.

Rational Molecular Design of Potent PLK1 PBD Domain-binding Phosphopeptides Using Preferential Amino Acid Building Blocks.

Mao XL, Wang KF, Zhu F, Pan ZH, Wu GM, Zhu HY.

Chem Biodivers. 2016 Aug;13(8):1103-10. doi: 10.1002/cbdv.201500513. Epub 2016 Aug 12.

PMID:
27450535
17.

The molecular basis of FHA domain:phosphopeptide binding specificity and implications for phospho-dependent signaling mechanisms.

Durocher D, Taylor IA, Sarbassova D, Haire LF, Westcott SL, Jackson SP, Smerdon SJ, Yaffe MB.

Mol Cell. 2000 Nov;6(5):1169-82.

19.

Identification of green tea catechins as potent inhibitors of the polo-box domain of polo-like kinase 1.

Shan HM, Shi Y, Quan J.

ChemMedChem. 2015 Jan;10(1):158-63. doi: 10.1002/cmdc.201402284. Epub 2014 Sep 5.

PMID:
25196850
20.

Polo-box motif targets a centrosome regulator, RanGTPase.

Jang YJ, Ji JH, Ahn JH, Hoe KL, Won M, Im DS, Chae SK, Song S, Yoo HS.

Biochem Biophys Res Commun. 2004 Dec 3;325(1):257-64.

PMID:
15522227

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