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Items: 1 to 20 of 57

1.

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation.

Bakkenist CJ, Kastan MB.

Nature. 2003 Jan 30;421(6922):499-506.

PMID:
12556884
2.

Constitutive phosphorylation of ATM in lymphoblastoid cell lines from patients with ICF syndrome without downstream kinase activity.

Goldstine JV, Nahas S, Gamo K, Gartler SM, Hansen RS, Roelfsema JH, Gatti RA, Marahrens Y.

DNA Repair (Amst). 2006 Apr 8;5(4):432-43. Epub 2006 Jan 19.

PMID:
16426903
3.

Telomeric protein Pin2/TRF1 as an important ATM target in response to double strand DNA breaks.

Kishi S, Zhou XZ, Ziv Y, Khoo C, Hill DE, Shiloh Y, Lu KP.

J Biol Chem. 2001 Aug 3;276(31):29282-91. Epub 2001 May 25.

4.

Autophosphorylation of ataxia-telangiectasia mutated is regulated by protein phosphatase 2A.

Goodarzi AA, Jonnalagadda JC, Douglas P, Young D, Ye R, Moorhead GB, Lees-Miller SP, Khanna KK.

EMBO J. 2004 Nov 10;23(22):4451-61. Epub 2004 Oct 28.

5.

Ionizing radiation induces ataxia telangiectasia mutated kinase (ATM)-mediated phosphorylation of LKB1/STK11 at Thr-366.

Sapkota GP, Deak M, Kieloch A, Morrice N, Goodarzi AA, Smythe C, Shiloh Y, Lees-Miller SP, Alessi DR.

Biochem J. 2002 Dec 1;368(Pt 2):507-16.

6.

Distinct functional domains of Nbs1 modulate the timing and magnitude of ATM activation after low doses of ionizing radiation.

Horejsí Z, Falck J, Bakkenist CJ, Kastan MB, Lukas J, Bartek J.

Oncogene. 2004 Apr 15;23(17):3122-7.

PMID:
15048089
7.

Identification of domains of ataxia-telangiectasia mutated required for nuclear localization and chromatin association.

Young DB, Jonnalagadda J, Gatei M, Jans DA, Meyn S, Khanna KK.

J Biol Chem. 2005 Jul 29;280(30):27587-94. Epub 2005 Jun 1.

8.

Ataxia-telangiectasia-mutated (ATM) is a T-antigen kinase that controls SV40 viral replication in vivo.

Shi Y, Dodson GE, Shaikh S, Rundell K, Tibbetts RS.

J Biol Chem. 2005 Dec 2;280(48):40195-200. Epub 2005 Oct 11.

9.

Regulation of ATM in DNA double strand break repair accounts for the radiosensitivity in human cells exposed to high linear energy transfer ionizing radiation.

Xue L, Yu D, Furusawa Y, Okayasu R, Tong J, Cao J, Fan S.

Mutat Res. 2009 Nov 2;670(1-2):15-23. doi: 10.1016/j.mrfmmm.2009.06.016. Epub 2009 Jul 5.

PMID:
19583974
10.
11.

DNA repair: Damage alert.

Bartek J, Lukas J.

Nature. 2003 Jan 30;421(6922):486-8. No abstract available.

PMID:
12556872
12.

[Low-dose radiation effects and intracellular signaling pathways].

Suzuki K, Kodama S, Watanabe M.

Yakugaku Zasshi. 2006 Oct;126(10):859-67. Review. Japanese.

13.

Ionizing radiation activates the ATM kinase throughout the cell cycle.

Pandita TK, Lieberman HB, Lim DS, Dhar S, Zheng W, Taya Y, Kastan MB.

Oncogene. 2000 Mar 9;19(11):1386-91.

14.
15.

Independent roles for nibrin and Mre11-Rad50 in the activation and function of Atm.

Cerosaletti K, Concannon P.

J Biol Chem. 2004 Sep 10;279(37):38813-9. Epub 2004 Jul 1.

16.

Hyperthermia activates a subset of ataxia-telangiectasia mutated effectors independent of DNA strand breaks and heat shock protein 70 status.

Hunt CR, Pandita RK, Laszlo A, Higashikubo R, Agarwal M, Kitamura T, Gupta A, Rief N, Horikoshi N, Baskaran R, Lee JH, Löbrich M, Paull TT, Roti Roti JL, Pandita TK.

Cancer Res. 2007 Apr 1;67(7):3010-7.

17.

Activation of ataxia telangiectasia mutated by DNA strand break-inducing agents correlates closely with the number of DNA double strand breaks.

Ismail IH, Nyström S, Nygren J, Hammarsten O.

J Biol Chem. 2005 Feb 11;280(6):4649-55. Epub 2004 Nov 15.

18.

ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex.

Lee JH, Paull TT.

Science. 2005 Apr 22;308(5721):551-4. Epub 2005 Mar 24. Erratum in: Science. 2005 Jun 24;308(5730):1870.

19.

Involvement of novel autophosphorylation sites in ATM activation.

Kozlov SV, Graham ME, Peng C, Chen P, Robinson PJ, Lavin MF.

EMBO J. 2006 Aug 9;25(15):3504-14. Epub 2006 Jul 13.

20.

Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks.

Cortez D, Wang Y, Qin J, Elledge SJ.

Science. 1999 Nov 5;286(5442):1162-6.

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