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Items: 1 to 20 of 120

1.

Rewiring MAP kinase pathways using alternative scaffold assembly mechanisms.

Park SH, Zarrinpar A, Lim WA.

Science. 2003 Feb 14;299(5609):1061-4. Epub 2003 Jan 2.

2.

Signal transduction. Imposing specificity on kinases.

Ptashne M, Gann A.

Science. 2003 Feb 14;299(5609):1025-7. No abstract available.

PMID:
12586931
3.

Conformational control of the Ste5 scaffold protein insulates against MAP kinase misactivation.

Zalatan JG, Coyle SM, Rajan S, Sidhu SS, Lim WA.

Science. 2012 Sep 7;337(6099):1218-22. doi: 10.1126/science.1220683. Epub 2012 Aug 9.

4.

Using engineered scaffold interactions to reshape MAP kinase pathway signaling dynamics.

Bashor CJ, Helman NC, Yan S, Lim WA.

Science. 2008 Mar 14;319(5869):1539-43. doi: 10.1126/science.1151153.

5.
6.
7.

Cell signaling. A sophisticated scaffold wields a new trick.

Breitkreutz A, Tyers M.

Science. 2006 Feb 10;311(5762):789-90. No abstract available.

PMID:
16469909
8.

Functional binding between Gbeta and the LIM domain of Ste5 is required to activate the MEKK Ste11.

Feng Y, Song LY, Kincaid E, Mahanty SK, Elion EA.

Curr Biol. 1998 Feb 26;8(5):267-78.

9.

The Ste5 scaffold allosterically modulates signaling output of the yeast mating pathway.

Bhattacharyya RP, Reményi A, Good MC, Bashor CJ, Falick AM, Lim WA.

Science. 2006 Feb 10;311(5762):822-6. Epub 2006 Jan 19.

10.

The Ste5 scaffold directs mating signaling by catalytically unlocking the Fus3 MAP kinase for activation.

Good M, Tang G, Singleton J, Reményi A, Lim WA.

Cell. 2009 Mar 20;136(6):1085-97. doi: 10.1016/j.cell.2009.01.049.

11.

Customized signaling with reconfigurable protein scaffolds.

Guye P, Weiss R.

Nat Biotechnol. 2008 May;26(5):526-8. doi: 10.1038/nbt0508-526. No abstract available.

PMID:
18464783
12.

A conserved docking site in MEKs mediates high-affinity binding to MAP kinases and cooperates with a scaffold protein to enhance signal transmission.

Bardwell AJ, Flatauer LJ, Matsukuma K, Thorner J, Bardwell L.

J Biol Chem. 2001 Mar 30;276(13):10374-86. Epub 2000 Dec 28.

13.

Persistent activation by constitutive Ste7 promotes Kss1-mediated invasive growth but fails to support Fus3-dependent mating in yeast.

Maleri S, Ge Q, Hackett EA, Wang Y, Dohlman HG, Errede B.

Mol Cell Biol. 2004 Oct;24(20):9221-38.

15.

JSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a Scaffold factor in the JNK signaling pathway.

Ito M, Yoshioka K, Akechi M, Yamashita S, Takamatsu N, Sugiyama K, Hibi M, Nakabeppu Y, Shiba T, Yamamoto KI.

Mol Cell Biol. 1999 Nov;19(11):7539-48.

16.
18.

Adjustable under-expression of yeast mating pathway proteins in Saccharomyces cerevisiae using a programmed ribosomal frameshift.

Choi MY, Park SH.

Appl Microbiol Biotechnol. 2016 Jun;100(11):4997-5005. doi: 10.1007/s00253-016-7335-9. Epub 2016 Feb 2.

PMID:
26837218
19.

The MAP kinase Fus3 associates with and phosphorylates the upstream signaling component Ste5.

Kranz JE, Satterberg B, Elion EA.

Genes Dev. 1994 Feb 1;8(3):313-27.

20.

Simple synthetic protein scaffolds can create adjustable artificial MAPK circuits in yeast and mammalian cells.

Ryu J, Park SH.

Sci Signal. 2015 Jun 30;8(383):ra66. doi: 10.1126/scisignal.aab3397.

PMID:
26126717

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