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Items: 1 to 20 of 136

1.

Mechanistic diversity and regulation of Type II fatty acid synthesis.

Marrakchi H, Zhang YM, Rock CO.

Biochem Soc Trans. 2002 Nov;30(Pt 6):1050-5. Review.

PMID:
12440970
2.

The application of computational methods to explore the diversity and structure of bacterial fatty acid synthase.

Zhang YM, Marrakchi H, White SW, Rock CO.

J Lipid Res. 2003 Jan;44(1):1-10. Review.

3.

The reductase steps of the type II fatty acid synthase as antimicrobial targets.

Zhang YM, Lu YJ, Rock CO.

Lipids. 2004 Nov;39(11):1055-60. Review.

PMID:
15726819
5.

Vibrio cholerae FabV defines a new class of enoyl-acyl carrier protein reductase.

Massengo-Tiassé RP, Cronan JE.

J Biol Chem. 2008 Jan 18;283(3):1308-16. Epub 2007 Nov 21.

6.

A new mechanism for anaerobic unsaturated fatty acid formation in Streptococcus pneumoniae.

Marrakchi H, Choi KH, Rock CO.

J Biol Chem. 2002 Nov 22;277(47):44809-16. Epub 2002 Sep 16.

7.

Phenylimidazole derivatives of 4-pyridone as dual inhibitors of bacterial enoyl-acyl carrier protein reductases FabI and FabK.

Kitagawa H, Ozawa T, Takahata S, Iida M, Saito J, Yamada M.

J Med Chem. 2007 Sep 20;50(19):4710-20. Epub 2007 Aug 22.

PMID:
17713898
8.

Inhibitors of FabI, an enzyme drug target in the bacterial fatty acid biosynthesis pathway.

Lu H, Tonge PJ.

Acc Chem Res. 2008 Jan;41(1):11-20. doi: 10.1021/ar700156e. Review.

PMID:
18193820
9.

Lipid biosynthesis as a target for antibacterial agents.

Heath RJ, White SW, Rock CO.

Prog Lipid Res. 2001 Nov;40(6):467-97. Review.

PMID:
11591436
10.
11.

Purification and biochemical characterization of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthases KasA and KasB.

Schaeffer ML, Agnihotri G, Volker C, Kallender H, Brennan PJ, Lonsdale JT.

J Biol Chem. 2001 Dec 14;276(50):47029-37. Epub 2001 Oct 12.

12.

The enoyl-[acyl-carrier-protein] reductases FabI and FabL from Bacillus subtilis.

Heath RJ, Su N, Murphy CK, Rock CO.

J Biol Chem. 2000 Dec 22;275(51):40128-33.

13.

Regulation of fatty acid metabolism in bacteria.

Fujita Y, Matsuoka H, Hirooka K.

Mol Microbiol. 2007 Nov;66(4):829-39. Epub 2007 Oct 2. Review.

14.
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17.

Fatty acid synthesis is a target for antibacterial activity of unsaturated fatty acids.

Zheng CJ, Yoo JS, Lee TG, Cho HY, Kim YH, Kim WG.

FEBS Lett. 2005 Sep 26;579(23):5157-62.

19.

Crystal structure of MabA from Mycobacterium tuberculosis, a reductase involved in long-chain fatty acid biosynthesis.

Cohen-Gonsaud M, Ducasse S, Hoh F, Zerbib D, Labesse G, Quemard A.

J Mol Biol. 2002 Jul 5;320(2):249-61.

PMID:
12079383
20.

Structure-function analysis of the acyl carrier protein synthase (AcpS) from Mycobacterium tuberculosis.

Dym O, Albeck S, Peleg Y, Schwarz A, Shakked Z, Burstein Y, Zimhony O.

J Mol Biol. 2009 Nov 6;393(4):937-50. doi: 10.1016/j.jmb.2009.08.065. Epub 2009 Sep 3.

PMID:
19733180

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