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Items: 1 to 20 of 124

1.

c-Cbl and Cbl-b regulate T cell responsiveness by promoting ligand-induced TCR down-modulation.

Naramura M, Jang IK, Kole H, Huang F, Haines D, Gu H.

Nat Immunol. 2002 Dec;3(12):1192-9. Epub 2002 Nov 4.

PMID:
12415267
2.

Lymphocyte signaling: Cbl sets the threshold for autoimmunity.

Rudd CE, Schneider H.

Curr Biol. 2000 May 4;10(9):R344-7. Review.

3.

Cbl-b regulates the CD28 dependence of T-cell activation.

Chiang YJ, Kole HK, Brown K, Naramura M, Fukuhara S, Hu RJ, Jang IK, Gutkind JS, Shevach E, Gu H.

Nature. 2000 Jan 13;403(6766):216-20.

PMID:
10646609
4.

Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells.

Krawczyk C, Bachmaier K, Sasaki T, Jones RG, Snapper SB, Bouchard D, Kozieradzki I, Ohashi PS, Alt FW, Penninger JM.

Immunity. 2000 Oct;13(4):463-73.

5.

Cutting edge: regulation of T cell activation threshold by CD28 costimulation through targeting Cbl-b for ubiquitination.

Zhang J, Bárdos T, Li D, Gál I, Vermes C, Xu J, Mikecz K, Finnegan A, Lipkowitz S, Glant TT.

J Immunol. 2002 Sep 1;169(5):2236-40.

6.
7.

Cbl-b regulates antigen-induced TCR down-regulation and IFN-gamma production by effector CD8 T cells without affecting functional avidity.

Shamim M, Nanjappa SG, Singh A, Plisch EH, LeBlanc SE, Walent J, Svaren J, Seroogy C, Suresh M.

J Immunol. 2007 Dec 1;179(11):7233-43.

8.
9.

Allelic exclusion of the TCR alpha-chain is an active process requiring TCR-mediated signaling and c-Cbl.

Niederberger N, Holmberg K, Alam SM, Sakati W, Naramura M, Gu H, Gascoigne NR.

J Immunol. 2003 May 1;170(9):4557-63.

10.

Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b.

Bachmaier K, Krawczyk C, Kozieradzki I, Kong YY, Sasaki T, Oliveira-dos-Santos A, Mariathasan S, Bouchard D, Wakeham A, Itie A, Le J, Ohashi PS, Sarosi I, Nishina H, Lipkowitz S, Penninger JM.

Nature. 2000 Jan 13;403(6766):211-6.

PMID:
10646608
11.

Activation of the Ras-related GTPase Rap1 by thymocyte TCR engagement and during selection.

Amsen D, Kruisbeek A, Bos JL, Reedquist K.

Eur J Immunol. 2000 Oct;30(10):2832-41.

12.

T-cell receptor-induced NF-kappaB activation is negatively regulated by E3 ubiquitin ligase Cbl-b.

Qiao G, Li Z, Molinero L, Alegre ML, Ying H, Sun Z, Penninger JM, Zhang J.

Mol Cell Biol. 2008 Apr;28(7):2470-80. doi: 10.1128/MCB.01505-07. Epub 2008 Jan 28.

13.

The involvement of the proto-oncogene p120 c-Cbl and ZAP-70 in CD2-mediated T cell activation.

Lin H, Martelli MP, Bierer BE.

Int Immunol. 2001 Jan;13(1):13-22.

PMID:
11133830
14.
15.

Integration of T cell receptor-dependent signaling pathways by adapter proteins.

Clements JL, Boerth NJ, Lee JR, Koretzky GA.

Annu Rev Immunol. 1999;17:89-108. Review.

PMID:
10358754
16.

Recruitment of Sprouty1 to immune synapse regulates T cell receptor signaling.

Lee JS, Lee JE, Oh YM, Park JB, Choi H, Choi CY, Kim IH, Lee SH, Choi K.

J Immunol. 2009 Dec 1;183(11):7178-86. doi: 10.4049/jimmunol.0803799. Epub 2009 Nov 13.

17.
18.

Inactivation of c-Cbl reverses neonatal lethality and T cell developmental arrest of SLP-76-deficient mice.

Chiang YJ, Sommers CL, Jordan MS, Gu H, Samelson LE, Koretzky GA, Hodes RJ.

J Exp Med. 2004 Jul 5;200(1):25-34.

19.
20.

Cbl and Cbl-b in T-cell regulation.

Liu YC, Gu H.

Trends Immunol. 2002 Mar;23(3):140-3.

PMID:
11864842

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