Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 127

1.

Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology.

Takahashi RH, Milner TA, Li F, Nam EE, Edgar MA, Yamaguchi H, Beal MF, Xu H, Greengard P, Gouras GK.

Am J Pathol. 2002 Nov;161(5):1869-79.

2.

Oligomerization of Alzheimer's beta-amyloid within processes and synapses of cultured neurons and brain.

Takahashi RH, Almeida CG, Kearney PF, Yu F, Lin MT, Milner TA, Gouras GK.

J Neurosci. 2004 Apr 7;24(14):3592-9.

3.

Progressive accumulation of amyloid-beta oligomers in Alzheimer's disease and in amyloid precursor protein transgenic mice is accompanied by selective alterations in synaptic scaffold proteins.

Pham E, Crews L, Ubhi K, Hansen L, Adame A, Cartier A, Salmon D, Galasko D, Michael S, Savas JN, Yates JR, Glabe C, Masliah E.

FEBS J. 2010 Jul;277(14):3051-67. doi: 10.1111/j.1742-4658.2010.07719.x. Epub 2010 Jun 22.

4.

Intraneuronal Aβ accumulation, amyloid plaques, and synapse pathology in Alzheimer's disease.

Capetillo-Zarate E, Gracia L, Tampellini D, Gouras GK.

Neurodegener Dis. 2012;10(1-4):56-9. doi: 10.1159/000334762. Epub 2012 Jan 21.

PMID:
22269167
5.

Accumulation of intraneuronal β-amyloid 42 peptides is associated with early changes in microtubule-associated protein 2 in neurites and synapses.

Takahashi RH, Capetillo-Zarate E, Lin MT, Milner TA, Gouras GK.

PLoS One. 2013;8(1):e51965. doi: 10.1371/journal.pone.0051965. Epub 2013 Jan 23.

6.

Intracellular Abeta42 activates p53 promoter: a pathway to neurodegeneration in Alzheimer's disease.

Ohyagi Y, Asahara H, Chui DH, Tsuruta Y, Sakae N, Miyoshi K, Yamada T, Kikuchi H, Taniwaki T, Murai H, Ikezoe K, Furuya H, Kawarabayashi T, Shoji M, Checler F, Iwaki T, Makifuchi T, Takeda K, Kira J, Tabira T.

FASEB J. 2005 Feb;19(2):255-7. Epub 2004 Nov 17.

PMID:
15548589
7.

The type of Aβ-related neuronal degeneration differs between amyloid precursor protein (APP23) and amyloid β-peptide (APP48) transgenic mice.

Rijal Upadhaya A, Scheibe F, Kosterin I, Abramowski D, Gerth J, Kumar S, Liebau S, Yamaguchi H, Walter J, Staufenbiel M, Thal DR.

Acta Neuropathol Commun. 2013 Nov 18;1:77. doi: 10.1186/2051-5960-1-77.

8.

Neuronal amyloid-β accumulation within cholinergic basal forebrain in ageing and Alzheimer's disease.

Baker-Nigh A, Vahedi S, Davis EG, Weintraub S, Bigio EH, Klein WL, Geula C.

Brain. 2015 Jun;138(Pt 6):1722-37. doi: 10.1093/brain/awv024. Epub 2015 Mar 1.

9.
10.

Autophagy-related protein 7 deficiency in amyloid β (Aβ) precursor protein transgenic mice decreases Aβ in the multivesicular bodies and induces Aβ accumulation in the Golgi.

Nilsson P, Sekiguchi M, Akagi T, Izumi S, Komori T, Hui K, Sörgjerd K, Tanaka M, Saito T, Iwata N, Saido TC.

Am J Pathol. 2015 Feb;185(2):305-13. doi: 10.1016/j.ajpath.2014.10.011. Epub 2014 Nov 26.

PMID:
25433221
11.

Intracellular amyloid-β accumulation in calcium-binding protein-deficient neurons leads to amyloid-β plaque formation in animal model of Alzheimer's disease.

Moon M, Hong HS, Nam DW, Baik SH, Song H, Kook SY, Kim YS, Lee J, Mook-Jung I.

J Alzheimers Dis. 2012;29(3):615-28. doi: 10.3233/JAD-2011-111778.

PMID:
22269161
12.

Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation.

Oakley H, Cole SL, Logan S, Maus E, Shao P, Craft J, Guillozet-Bongaarts A, Ohno M, Disterhoft J, Van Eldik L, Berry R, Vassar R.

J Neurosci. 2006 Oct 4;26(40):10129-40.

13.

Reducing Ribosomal Protein S6 Kinase 1 Expression Improves Spatial Memory and Synaptic Plasticity in a Mouse Model of Alzheimer's Disease.

Caccamo A, Branca C, Talboom JS, Shaw DM, Turner D, Ma L, Messina A, Huang Z, Wu J, Oddo S.

J Neurosci. 2015 Oct 14;35(41):14042-56. doi: 10.1523/JNEUROSCI.2781-15.2015.

14.

The inside-out amyloid hypothesis and synapse pathology in Alzheimer's disease.

Gouras GK, Willén K, Faideau M.

Neurodegener Dis. 2014;13(2-3):142-6. doi: 10.1159/000354776. Epub 2013 Sep 24. Review.

PMID:
24080821
15.

Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models.

Natunen T, Takalo M, Kemppainen S, Leskelä S, Marttinen M, Kurkinen KMA, Pursiheimo JP, Sarajärvi T, Viswanathan J, Gabbouj S, Solje E, Tahvanainen E, Pirttimäki T, Kurki M, Paananen J, Rauramaa T, Miettinen P, Mäkinen P, Leinonen V, Soininen H, Airenne K, Tanzi RE, Tanila H, Haapasalo A, Hiltunen M.

Neurobiol Dis. 2016 Jan;85:187-205. doi: 10.1016/j.nbd.2015.11.005. Epub 2015 Nov 10.

PMID:
26563932
16.

Efficacy and toxicity of clioquinol treatment and A-beta42 inoculation in the APP/PSI mouse model of Alzheimer's disease.

Zhang YH, Raymick J, Sarkar S, Lahiri DK, Ray B, Holtzman D, Dumas M, Schmued LC.

Curr Alzheimer Res. 2013 Jun;10(5):494-506.

PMID:
23627708
17.

Ultrastructural and behavioural changes precede amyloid deposition in a transgenic model of Alzheimer's disease.

Richardson JC, Kendal CE, Anderson R, Priest F, Gower E, Soden P, Gray R, Topps S, Howlett DR, Lavender D, Clarke NJ, Barnes JC, Haworth R, Stewart MG, Rupniak HT.

Neuroscience. 2003;122(1):213-28.

PMID:
14596862
18.
19.

Early neuronal loss and axonal/presynaptic damage is associated with accelerated amyloid-β accumulation in AβPP/PS1 Alzheimer's disease mice subiculum.

Trujillo-Estrada L, Dávila JC, Sánchez-Mejias E, Sánchez-Varo R, Gomez-Arboledas A, Vizuete M, Vitorica J, Gutiérrez A.

J Alzheimers Dis. 2014;42(2):521-41. doi: 10.3233/JAD-140495.

PMID:
24927710
20.

Telomere shortening reduces Alzheimer's disease amyloid pathology in mice.

Rolyan H, Scheffold A, Heinrich A, Begus-Nahrmann Y, Langkopf BH, Hölter SM, Vogt-Weisenhorn DM, Liss B, Wurst W, Lie DC, Thal DR, Biber K, Rudolph KL.

Brain. 2011 Jul;134(Pt 7):2044-56. doi: 10.1093/brain/awr133. Epub 2011 Jun 14.

PMID:
21672962

Supplemental Content

Support Center