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Items: 1 to 20 of 437

1.

Sprouty1 and Sprouty2 provide a control mechanism for the Ras/MAPK signalling pathway.

Hanafusa H, Torii S, Yasunaga T, Nishida E.

Nat Cell Biol. 2002 Nov;4(11):850-8.

PMID:
12402043
2.
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4.

EGFR and FGFR signaling through FRS2 is subject to negative feedback control by ERK1/2.

Wu Y, Chen Z, Ullrich A.

Biol Chem. 2003 Aug;384(8):1215-26.

PMID:
12974390
5.
6.

The Shb adaptor protein binds to tyrosine 766 in the FGFR-1 and regulates the Ras/MEK/MAPK pathway via FRS2 phosphorylation in endothelial cells.

Cross MJ, Lu L, Magnusson P, Nyqvist D, Holmqvist K, Welsh M, Claesson-Welsh L.

Mol Biol Cell. 2002 Aug;13(8):2881-93.

7.

A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway.

Kouhara H, Hadari YR, Spivak-Kroizman T, Schilling J, Bar-Sagi D, Lax I, Schlessinger J.

Cell. 1997 May 30;89(5):693-702.

8.

Identification of a dominant negative mutant of Sprouty that potentiates fibroblast growth factor- but not epidermal growth factor-induced ERK activation.

Sasaki A, Taketomi T, Wakioka T, Kato R, Yoshimura A.

J Biol Chem. 2001 Sep 28;276(39):36804-8. Epub 2001 Aug 8.

9.
10.

Tyrosyl phosphorylation of Shp2 is required for normal ERK activation in response to some, but not all, growth factors.

Araki T, Nawa H, Neel BG.

J Biol Chem. 2003 Oct 24;278(43):41677-84. Epub 2003 Aug 14.

11.
12.

SNT1/FRS2 mediates germinal vesicle breakdown induced by an activated FGF receptor1 in Xenopus oocytes.

Mood K, Friesel R, Daar IO.

J Biol Chem. 2002 Sep 6;277(36):33196-204. Epub 2002 Jun 24.

14.

Mammalian sprouty proteins inhibit cell growth and differentiation by preventing ras activation.

Gross I, Bassit B, Benezra M, Licht JD.

J Biol Chem. 2001 Dec 7;276(49):46460-8. Epub 2001 Oct 3.

15.

Identification of SNT/FRS2 docking site on RET receptor tyrosine kinase and its role for signal transduction.

Kurokawa K, Iwashita T, Murakami H, Hayashi H, Kawai K, Takahashi M.

Oncogene. 2001 Apr 12;20(16):1929-38.

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A Src homology 3-binding sequence on the C terminus of Sprouty2 is necessary for inhibition of the Ras/ERK pathway downstream of fibroblast growth factor receptor stimulation.

Lao DH, Chandramouli S, Yusoff P, Fong CW, Saw TY, Tai LP, Yu CY, Leong HF, Guy GR.

J Biol Chem. 2006 Oct 6;281(40):29993-30000. Epub 2006 Aug 7.

19.

Helicobacter pylori CagA induces Ras-independent morphogenetic response through SHP-2 recruitment and activation.

Higashi H, Nakaya A, Tsutsumi R, Yokoyama K, Fujii Y, Ishikawa S, Higuchi M, Takahashi A, Kurashima Y, Teishikata Y, Tanaka S, Azuma T, Hatakeyama M.

J Biol Chem. 2004 Apr 23;279(17):17205-16. Epub 2004 Feb 12.

20.

hSef inhibits PC-12 cell differentiation by interfering with Ras-mitogen-activated protein kinase MAPK signaling.

Xiong S, Zhao Q, Rong Z, Huang G, Huang Y, Chen P, Zhang S, Liu L, Chang Z.

J Biol Chem. 2003 Dec 12;278(50):50273-82. Epub 2003 Sep 4.

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