Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 437


Sprouty1 and Sprouty2 provide a control mechanism for the Ras/MAPK signalling pathway.

Hanafusa H, Torii S, Yasunaga T, Nishida E.

Nat Cell Biol. 2002 Nov;4(11):850-8.


EGFR and FGFR signaling through FRS2 is subject to negative feedback control by ERK1/2.

Wu Y, Chen Z, Ullrich A.

Biol Chem. 2003 Aug;384(8):1215-26.


The Shb adaptor protein binds to tyrosine 766 in the FGFR-1 and regulates the Ras/MEK/MAPK pathway via FRS2 phosphorylation in endothelial cells.

Cross MJ, Lu L, Magnusson P, Nyqvist D, Holmqvist K, Welsh M, Claesson-Welsh L.

Mol Biol Cell. 2002 Aug;13(8):2881-93.


A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway.

Kouhara H, Hadari YR, Spivak-Kroizman T, Schilling J, Bar-Sagi D, Lax I, Schlessinger J.

Cell. 1997 May 30;89(5):693-702.


Identification of a dominant negative mutant of Sprouty that potentiates fibroblast growth factor- but not epidermal growth factor-induced ERK activation.

Sasaki A, Taketomi T, Wakioka T, Kato R, Yoshimura A.

J Biol Chem. 2001 Sep 28;276(39):36804-8. Epub 2001 Aug 8.


Tyrosyl phosphorylation of Shp2 is required for normal ERK activation in response to some, but not all, growth factors.

Araki T, Nawa H, Neel BG.

J Biol Chem. 2003 Oct 24;278(43):41677-84. Epub 2003 Aug 14.


SNT1/FRS2 mediates germinal vesicle breakdown induced by an activated FGF receptor1 in Xenopus oocytes.

Mood K, Friesel R, Daar IO.

J Biol Chem. 2002 Sep 6;277(36):33196-204. Epub 2002 Jun 24.


Mammalian sprouty proteins inhibit cell growth and differentiation by preventing ras activation.

Gross I, Bassit B, Benezra M, Licht JD.

J Biol Chem. 2001 Dec 7;276(49):46460-8. Epub 2001 Oct 3.


Identification of SNT/FRS2 docking site on RET receptor tyrosine kinase and its role for signal transduction.

Kurokawa K, Iwashita T, Murakami H, Hayashi H, Kawai K, Takahashi M.

Oncogene. 2001 Apr 12;20(16):1929-38.


A Src homology 3-binding sequence on the C terminus of Sprouty2 is necessary for inhibition of the Ras/ERK pathway downstream of fibroblast growth factor receptor stimulation.

Lao DH, Chandramouli S, Yusoff P, Fong CW, Saw TY, Tai LP, Yu CY, Leong HF, Guy GR.

J Biol Chem. 2006 Oct 6;281(40):29993-30000. Epub 2006 Aug 7.


Helicobacter pylori CagA induces Ras-independent morphogenetic response through SHP-2 recruitment and activation.

Higashi H, Nakaya A, Tsutsumi R, Yokoyama K, Fujii Y, Ishikawa S, Higuchi M, Takahashi A, Kurashima Y, Teishikata Y, Tanaka S, Azuma T, Hatakeyama M.

J Biol Chem. 2004 Apr 23;279(17):17205-16. Epub 2004 Feb 12.


hSef inhibits PC-12 cell differentiation by interfering with Ras-mitogen-activated protein kinase MAPK signaling.

Xiong S, Zhao Q, Rong Z, Huang G, Huang Y, Chen P, Zhang S, Liu L, Chang Z.

J Biol Chem. 2003 Dec 12;278(50):50273-82. Epub 2003 Sep 4.

Supplemental Content

Support Center