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Items: 1 to 20 of 170

1.

Transglutaminase 2: an enigmatic enzyme with diverse functions.

Fesus L, Piacentini M.

Trends Biochem Sci. 2002 Oct;27(10):534-9. Review.

PMID:
12368090
2.

Some lessons from the tissue transglutaminase knockout mouse.

Sarang Z, Tóth B, Balajthy Z, Köröskényi K, Garabuczi E, Fésüs L, Szondy Z.

Amino Acids. 2009 Apr;36(4):625-31. doi: 10.1007/s00726-008-0130-x. Epub 2008 Jun 27. Review.

PMID:
18584284
3.

Transglutaminase 2: a multi-functional protein in multiple subcellular compartments.

Park D, Choi SS, Ha KS.

Amino Acids. 2010 Aug;39(3):619-31. doi: 10.1007/s00726-010-0500-z. Epub 2010 Feb 11. Review.

PMID:
20148342
4.

Recent advances in understanding the roles of transglutaminase 2 in alcoholic steatohepatitis.

Tatsukawa H, Kojima S.

Cell Biol Int. 2010 Feb 22;34(3):325-34. doi: 10.1042/CBI20090130. Review.

PMID:
20192918
5.

Crystal structure of transglutaminase 2 with GTP complex and amino acid sequence evidence of evolution of GTP binding site.

Jang TH, Lee DS, Choi K, Jeong EM, Kim IG, Kim YW, Chun JN, Jeon JH, Park HH.

PLoS One. 2014 Sep 5;9(9):e107005. doi: 10.1371/journal.pone.0107005. eCollection 2014.

6.

Functional significance of five noncanonical Ca2+-binding sites of human transglutaminase 2 characterized by site-directed mutagenesis.

Király R, Csosz E, Kurtán T, Antus S, Szigeti K, Simon-Vecsei Z, Korponay-Szabó IR, Keresztessy Z, Fésüs L.

FEBS J. 2009 Dec;276(23):7083-96. doi: 10.1111/j.1742-4658.2009.07420.x. Epub 2009 Oct 29.

7.

Type 2 transglutaminase in neurodegenerative diseases: the mitochondrial connection.

Malorni W, Farrace MG, Rodolfo C, Piacentini M.

Curr Pharm Des. 2008;14(3):278-88. Review.

PMID:
18220838
8.

External GTP-bound transglutaminase 2 is a molecular switch for chondrocyte hypertrophic differentiation and calcification.

Johnson KA, Terkeltaub RA.

J Biol Chem. 2005 Apr 15;280(15):15004-12. Epub 2005 Feb 3.

9.

Mutation of a critical arginine in the GTP-binding site of transglutaminase 2 disinhibits intracellular cross-linking activity.

Begg GE, Holman SR, Stokes PH, Matthews JM, Graham RM, Iismaa SE.

J Biol Chem. 2006 May 5;281(18):12603-9. Epub 2006 Mar 7.

10.

Functional characterization of naturally occurring transglutaminase 2 mutants implicated in early-onset type 2 diabetes.

Salter NW, Ande SR, Nguyen HK, Nyomba BL, Mishra S.

J Mol Endocrinol. 2012 Apr 2;48(3):203-16. doi: 10.1530/JME-11-0064. Print 2012 Jun.

PMID:
22394545
11.

Regulation of ATPase activity of transglutaminase 2 by MT1-MMP: implications for mineralization of MC3T3-E1 osteoblast cultures.

Nakano Y, Forsprecher J, Kaartinen MT.

J Cell Physiol. 2010 Apr;223(1):260-9. doi: 10.1002/jcp.22034.

PMID:
20049897
12.

Transglutaminase-2 interaction with heparin: identification of a heparin binding site that regulates cell adhesion to fibronectin-transglutaminase-2 matrix.

Lortat-Jacob H, Burhan I, Scarpellini A, Thomas A, Imberty A, Vivès RR, Johnson T, Gutierrez A, Verderio EA.

J Biol Chem. 2012 May 25;287(22):18005-17. doi: 10.1074/jbc.M111.337089. Epub 2012 Mar 22.

13.

Transglutaminase 2 suppresses apoptosis by modulating caspase 3 and NF-kappaB activity in hypoxic tumor cells.

Jang GY, Jeon JH, Cho SY, Shin DM, Kim CW, Jeong EM, Bae HC, Kim TW, Lee SH, Choi Y, Lee DS, Park SC, Kim IG.

Oncogene. 2010 Jan 21;29(3):356-67. doi: 10.1038/onc.2009.342. Epub 2009 Oct 19.

PMID:
19838207
14.

Substrate preference of transglutaminase 2 revealed by logistic regression analysis and intrinsic disorder examination.

Csosz E, Bagossi P, Nagy Z, Dosztanyi Z, Simon I, Fesus L.

J Mol Biol. 2008 Nov 7;383(2):390-402. doi: 10.1016/j.jmb.2008.08.026. Epub 2008 Aug 22.

PMID:
18761350
15.

Transglutaminase 2: a molecular Swiss army knife.

Gundemir S, Colak G, Tucholski J, Johnson GV.

Biochim Biophys Acta. 2012 Feb;1823(2):406-19. doi: 10.1016/j.bbamcr.2011.09.012. Epub 2011 Oct 10. Review.

16.

Transglutaminase 2: biology, relevance to neurodegenerative diseases and therapeutic implications.

Grosso H, Mouradian MM.

Pharmacol Ther. 2012 Mar;133(3):392-410. doi: 10.1016/j.pharmthera.2011.12.003. Epub 2011 Dec 22. Review.

PMID:
22212614
17.

Phosphorylation of transglutaminase 2 by PKA at Ser216 creates 14-3-3 binding sites.

Mishra S, Murphy LJ.

Biochem Biophys Res Commun. 2006 Sep 8;347(4):1166-70. Epub 2006 Jul 17.

PMID:
16870138
18.

A crucial sequence for transglutaminase type 2 extracellular trafficking in renal tubular epithelial cells lies in its N-terminal beta-sandwich domain.

Chou CY, Streets AJ, Watson PF, Huang L, Verderio EA, Johnson TS.

J Biol Chem. 2011 Aug 5;286(31):27825-35. doi: 10.1074/jbc.M111.226340. Epub 2011 Jun 7.

19.

Crosslinking and G-protein functions of transglutaminase 2 contribute differentially to fibroblast wound healing responses.

Stephens P, Grenard P, Aeschlimann P, Langley M, Blain E, Errington R, Kipling D, Thomas D, Aeschlimann D.

J Cell Sci. 2004 Jul 1;117(Pt 15):3389-403. Epub 2004 Jun 15.

20.

Enhanced osteoblast adhesion on transglutaminase 2-crosslinked fibronectin.

Forsprecher J, Wang Z, Nelea V, Kaartinen MT.

Amino Acids. 2009 Apr;36(4):747-53. doi: 10.1007/s00726-008-0125-7. Epub 2008 Jul 5.

PMID:
18604470

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