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Items: 1 to 20 of 186

1.

53BP1, a mediator of the DNA damage checkpoint.

Wang B, Matsuoka S, Carpenter PB, Elledge SJ.

Science. 2002 Nov 15;298(5597):1435-8. Epub 2002 Oct 3.

2.
3.

MDC1 is a mediator of the mammalian DNA damage checkpoint.

Stewart GS, Wang B, Bignell CR, Taylor AM, Elledge SJ.

Nature. 2003 Feb 27;421(6926):961-6.

PMID:
12607005
4.

DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1.

Fernandez-Capetillo O, Chen HT, Celeste A, Ward I, Romanienko PJ, Morales JC, Naka K, Xia Z, Camerini-Otero RD, Motoyama N, Carpenter PB, Bonner WM, Chen J, Nussenzweig A.

Nat Cell Biol. 2002 Dec;4(12):993-7.

PMID:
12447390
5.

A mitotic phosphorylation feedback network connects Cdk1, Plk1, 53BP1, and Chk2 to inactivate the G(2)/M DNA damage checkpoint.

van Vugt MA, Gardino AK, Linding R, Ostheimer GJ, Reinhardt HC, Ong SE, Tan CS, Miao H, Keezer SM, Li J, Pawson T, Lewis TA, Carr SA, Smerdon SJ, Brummelkamp TR, Yaffe MB.

PLoS Biol. 2010 Jan 26;8(1):e1000287. doi: 10.1371/journal.pbio.1000287.

6.

NFBD1/MDC1, 53BP1 and BRCA1 have both redundant and unique roles in the ATM pathway.

Wilson KA, Stern DF.

Cell Cycle. 2008 Nov 15;7(22):3584-94. Epub 2008 Nov 29.

7.

STAT-1 facilitates the ATM activated checkpoint pathway following DNA damage.

Townsend PA, Cragg MS, Davidson SM, McCormick J, Barry S, Lawrence KM, Knight RA, Hubank M, Chen PL, Latchman DS, Stephanou A.

J Cell Sci. 2005 Apr 15;118(Pt 8):1629-39. Epub 2005 Mar 22. Retraction in: J Cell Sci. 2015 Mar 1;128(5):1064.

8.

Polo-like kinase 1 inhibits DNA damage response during mitosis.

Benada J, Burdová K, Lidak T, von Morgen P, Macurek L.

Cell Cycle. 2015;14(2):219-31. doi: 10.4161/15384101.2014.977067.

9.

A DNA damage checkpoint response in telomere-initiated senescence.

d'Adda di Fagagna F, Reaper PM, Clay-Farrace L, Fiegler H, Carr P, Von Zglinicki T, Saretzki G, Carter NP, Jackson SP.

Nature. 2003 Nov 13;426(6963):194-8. Epub 2003 Nov 5.

PMID:
14608368
10.

Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways.

Rappold I, Iwabuchi K, Date T, Chen J.

J Cell Biol. 2001 Apr 30;153(3):613-20. Erratum in: J Cell Biol 2001 Jul 23;154(2):469.

11.

Phosphorylation and rapid relocalization of 53BP1 to nuclear foci upon DNA damage.

Anderson L, Henderson C, Adachi Y.

Mol Cell Biol. 2001 Mar;21(5):1719-29.

12.

Human T-cell leukemia virus-I tax oncoprotein functionally targets a subnuclear complex involved in cellular DNA damage-response.

Haoudi A, Daniels RC, Wong E, Kupfer G, Semmes OJ.

J Biol Chem. 2003 Sep 26;278(39):37736-44. Epub 2003 Jul 2.

13.

53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer.

DiTullio RA Jr, Mochan TA, Venere M, Bartkova J, Sehested M, Bartek J, Halazonetis TD.

Nat Cell Biol. 2002 Dec;4(12):998-1002. Erratum in: Nat Cell Biol. 2003 Jan;5(1):84..

PMID:
12447382
14.

p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks.

Schultz LB, Chehab NH, Malikzay A, Halazonetis TD.

J Cell Biol. 2000 Dec 25;151(7):1381-90.

15.

The p53-inducible gene 3 (PIG3) contributes to early cellular response to DNA damage.

Lee JH, Kang Y, Khare V, Jin ZY, Kang MY, Yoon Y, Hyun JW, Chung MH, Cho SI, Jun JY, Chang IY, You HJ.

Oncogene. 2010 Mar 11;29(10):1431-50. doi: 10.1038/onc.2009.438. Epub 2009 Dec 21.

PMID:
20023697
16.

Vaccinia-related kinase 1 (VRK1) is an upstream nucleosomal kinase required for the assembly of 53BP1 foci in response to ionizing radiation-induced DNA damage.

Sanz-GarcĂ­a M, Monsalve DM, Sevilla A, Lazo PA.

J Biol Chem. 2012 Jul 6;287(28):23757-68. doi: 10.1074/jbc.M112.353102. Epub 2012 May 22.

17.

TTK/hMps1 participates in the regulation of DNA damage checkpoint response by phosphorylating CHK2 on threonine 68.

Wei JH, Chou YF, Ou YH, Yeh YH, Tyan SW, Sun TP, Shen CY, Shieh SY.

J Biol Chem. 2005 Mar 4;280(9):7748-57. Epub 2004 Dec 23.

18.

PTIP regulates 53BP1 and SMC1 at the DNA damage sites.

Wu J, Prindle MJ, Dressler GR, Yu X.

J Biol Chem. 2009 Jul 3;284(27):18078-84. doi: 10.1074/jbc.M109.002527. Epub 2009 May 4.

19.
20.

Growth of persistent foci of DNA damage checkpoint factors is essential for amplification of G1 checkpoint signaling.

Yamauchi M, Oka Y, Yamamoto M, Niimura K, Uchida M, Kodama S, Watanabe M, Sekine I, Yamashita S, Suzuki K.

DNA Repair (Amst). 2008 Mar 1;7(3):405-17. doi: 10.1016/j.dnarep.2007.11.011. Epub 2008 Jan 8.

PMID:
18248856

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