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Items: 1 to 20 of 109

1.

Binding of the PX domain of p47(phox) to phosphatidylinositol 3,4-bisphosphate and phosphatidic acid is masked by an intramolecular interaction.

Karathanassis D, Stahelin RV, Bravo J, Perisic O, Pacold CM, Cho W, Williams RL.

EMBO J. 2002 Oct 1;21(19):5057-68.

2.

Membrane binding mechanisms of the PX domains of NADPH oxidase p40phox and p47phox.

Stahelin RV, Burian A, Bruzik KS, Murray D, Cho W.

J Biol Chem. 2003 Apr 18;278(16):14469-79. Epub 2003 Jan 29.

4.

Phosphorylation of p47phox directs phox homology domain from SH3 domain toward phosphoinositides, leading to phagocyte NADPH oxidase activation.

Ago T, Kuribayashi F, Hiroaki H, Takeya R, Ito T, Kohda D, Sumimoto H.

Proc Natl Acad Sci U S A. 2003 Apr 15;100(8):4474-9. Epub 2003 Apr 2.

5.

The crystal structure of the PX domain from p40(phox) bound to phosphatidylinositol 3-phosphate.

Bravo J, Karathanassis D, Pacold CM, Pacold ME, Ellson CD, Anderson KE, Butler PJ, Lavenir I, Perisic O, Hawkins PT, Stephens L, Williams RL.

Mol Cell. 2001 Oct;8(4):829-39.

6.

Cooperation of p40(phox) with p47(phox) for Nox2-based NADPH oxidase activation during Fcγ receptor (FcγR)-mediated phagocytosis: mechanism for acquisition of p40(phox) phosphatidylinositol 3-phosphate (PI(3)P) binding.

Ueyama T, Nakakita J, Nakamura T, Kobayashi T, Kobayashi T, Son J, Sakuma M, Sakaguchi H, Leto TL, Saito N.

J Biol Chem. 2011 Nov 25;286(47):40693-705. doi: 10.1074/jbc.M111.237289. Epub 2011 Sep 28.

7.

Atypical membrane-embedded phosphatidylinositol 3,4-bisphosphate (PI(3,4)P2)-binding site on p47(phox) Phox homology (PX) domain revealed by NMR.

Stampoulis P, Ueda T, Matsumoto M, Terasawa H, Miyano K, Sumimoto H, Shimada I.

J Biol Chem. 2012 May 18;287(21):17848-59. doi: 10.1074/jbc.M111.332874. Epub 2012 Apr 4.

10.

Assembly of the phagocyte NADPH oxidase: binding of Src homology 3 domains to proline-rich targets.

Leto TL, Adams AG, de Mendez I.

Proc Natl Acad Sci U S A. 1994 Oct 25;91(22):10650-4.

11.

The PX domain as a novel phosphoinositide- binding module.

Ago T, Takeya R, Hiroaki H, Kuribayashi F, Ito T, Kohda D, Sumimoto H.

Biochem Biophys Res Commun. 2001 Sep 28;287(3):733-8.

PMID:
11563857
12.

The p40phox and p47phox PX domains of NADPH oxidase target cell membranes via direct and indirect recruitment by phosphoinositides.

Zhan Y, Virbasius JV, Song X, Pomerleau DP, Zhou GW.

J Biol Chem. 2002 Feb 8;277(6):4512-8. Epub 2001 Nov 29.

13.

Mutations in the PX-SH3A linker of p47phox decouple PI(3,4)P2 binding from NADPH oxidase activation.

Shen K, Sergeant S, Hantgan RR, McPhail LC, Horita DA.

Biochemistry. 2008 Aug 26;47(34):8855-65. doi: 10.1021/bi8005847. Epub 2008 Aug 2.

14.
15.

Mapping of functional domains in p47(phox) involved in the activation of NADPH oxidase by "peptide walking".

Morozov I, Lotan O, Joseph G, Gorzalczany Y, Pick E.

J Biol Chem. 1998 Jun 19;273(25):15435-44.

16.

Mechanism of membrane binding of the phospholipase D1 PX domain.

Stahelin RV, Ananthanarayanan B, Blatner NR, Singh S, Bruzik KS, Murray D, Cho W.

J Biol Chem. 2004 Dec 24;279(52):54918-26. Epub 2004 Oct 8.

18.

Solution structure of the PX domain, a target of the SH3 domain.

Hiroaki H, Ago T, Ito T, Sumimoto H, Kohda D.

Nat Struct Biol. 2001 Jun;8(6):526-30.

PMID:
11373621
20.

Phosphatidylinositol 3-phosphate-dependent and -independent functions of p40phox in activation of the neutrophil NADPH oxidase.

Bissonnette SA, Glazier CM, Stewart MQ, Brown GE, Ellson CD, Yaffe MB.

J Biol Chem. 2008 Jan 25;283(4):2108-19. Epub 2007 Nov 20.

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