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Items: 1 to 20 of 108


Specification of the mammalian cochlea is dependent on Sonic hedgehog.

Riccomagno MM, Martinu L, Mulheisen M, Wu DK, Epstein DJ.

Genes Dev. 2002 Sep 15;16(18):2365-78.


Otic ablation of smoothened reveals direct and indirect requirements for Hedgehog signaling in inner ear development.

Brown AS, Epstein DJ.

Development. 2011 Sep;138(18):3967-76. doi: 10.1242/dev.066126. Epub 2011 Aug 10.


Opposing gradients of Gli repressor and activators mediate Shh signaling along the dorsoventral axis of the inner ear.

Bok J, Dolson DK, Hill P, Rüther U, Epstein DJ, Wu DK.

Development. 2007 May;134(9):1713-22. Epub 2007 Mar 29.


Six1 controls patterning of the mouse otic vesicle.

Ozaki H, Nakamura K, Funahashi J, Ikeda K, Yamada G, Tokano H, Okamura HO, Kitamura K, Muto S, Kotaki H, Sudo K, Horai R, Iwakura Y, Kawakami K.

Development. 2004 Feb;131(3):551-62. Epub 2003 Dec 24.


Wnt-dependent regulation of inner ear morphogenesis is balanced by the opposing and supporting roles of Shh.

Riccomagno MM, Takada S, Epstein DJ.

Genes Dev. 2005 Jul 1;19(13):1612-23. Epub 2005 Jun 16.


The role of Six1 in mammalian auditory system development.

Zheng W, Huang L, Wei ZB, Silvius D, Tang B, Xu PX.

Development. 2003 Sep;130(17):3989-4000.


The role of Pax2 in mouse inner ear development.

Burton Q, Cole LK, Mulheisen M, Chang W, Wu DK.

Dev Biol. 2004 Aug 1;272(1):161-75.


Dorsoventral patterning is established in the telencephalon of mutants lacking both Gli3 and Hedgehog signaling.

Rallu M, Machold R, Gaiano N, Corbin JG, McMahon AP, Fishell G.

Development. 2002 Nov;129(21):4963-74.


Sonic hedgehog regulates otic capsule chondrogenesis and inner ear development in the mouse embryo.

Liu W, Li G, Chien JS, Raft S, Zhang H, Chiang C, Frenz DA.

Dev Biol. 2002 Aug 15;248(2):240-50.


Eya1 regulates the growth of otic epithelium and interacts with Pax2 during the development of all sensory areas in the inner ear.

Zou D, Silvius D, Rodrigo-Blomqvist S, Enerbäck S, Xu PX.

Dev Biol. 2006 Oct 15;298(2):430-41. Epub 2006 Jul 7.


A restrictive role for Hedgehog signalling during otic specification in Xenopus.

Koebernick K, Hollemann T, Pieler T.

Dev Biol. 2003 Aug 15;260(2):325-38.


Role of the hindbrain in dorsoventral but not anteroposterior axial specification of the inner ear.

Bok J, Bronner-Fraser M, Wu DK.

Development. 2005 May;132(9):2115-24. Epub 2005 Mar 23.


[Sonic Hedgehog signaling pathway and regulation of inner ear development].

Chen ZQ, Han XH, Cao X.

Yi Chuan. 2013 Sep;35(9):1058-64. Review. Chinese.


Expression of Pax2 and patterning of the chick inner ear.

Hutson MR, Lewis JE, Nguyen-Luu D, Lindberg KH, Barald KF.

J Neurocytol. 1999 Oct-Nov;28(10-11):795-807.


Otx1 and Otx2 activities are required for the normal development of the mouse inner ear.

Morsli H, Tuorto F, Choo D, Postiglione MP, Simeone A, Wu DK.

Development. 1999 Jun;126(11):2335-43.


Molecular mechanisms underlying inner ear patterning defects in kreisler mutants.

Choo D, Ward J, Reece A, Dou H, Lin Z, Greinwald J.

Dev Biol. 2006 Jan 15;289(2):308-17. Epub 2005 Dec 1.


Two regulatory genes, cNkx5-1 and cPax2, show different responses to local signals during otic placode and vesicle formation in the chick embryo.

Herbrand H, Guthrie S, Hadrys T, Hoffmann S, Arnold HH, Rinkwitz-Brandt S, Bober E.

Development. 1998 Feb;125(4):645-54.


Tbx1 and Brn4 regulate retinoic acid metabolic genes during cochlear morphogenesis.

Braunstein EM, Monks DC, Aggarwal VS, Arnold JS, Morrow BE.

BMC Dev Biol. 2009 May 29;9:31. doi: 10.1186/1471-213X-9-31.


Direct action of the nodal-related signal cyclops in induction of sonic hedgehog in the ventral midline of the CNS.

Müller F, Albert S, Blader P, Fischer N, Hallonet M, Strähle U.

Development. 2000 Sep;127(18):3889-97.

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